Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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The Pseudomonas aeruginosa exoenzyme Y impairs endothelial cell proliferation and vascular repair following lung injury. | Exoenzyme Y (ExoY) is a Pseudomonas aeruginosa toxin that is introduced into host cells through the type 3 secretion system (T3SS). Once inside the host cell cytoplasm, ExoY generates cyclic nucleotides that cause tau phosphorylation and microtubule breakdown. Microtubule breakdown causes interendothelial cell gap form... | ['Animals', 'Bacterial Proteins', 'Cell Proliferation', 'Cyclic AMP', 'Edema', 'Endothelial Cells', 'Glucosyltransferases', 'Host-Pathogen Interactions', 'Lung', 'Lung Injury', 'Male', 'Microvessels', 'Pneumonia, Bacterial', 'Pseudomonas Infections', 'Pseudomonas aeruginosa', 'Rats'] | 24,705,722 | [['B01.050'], ['D12.776.097'], ['G04.161.750', 'G07.345.249.410.750'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['C23.888.277'], ['A11.436.275'], ['D08.811.913.400.450.460'], ['G06.462', 'G16.527.200'], ['A04.411'], ['C08.381.520', 'C26.891.554'], ['A07.015.461']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Plastic changes in neuropeptide Y receptor subtypes in experimental models of limbic seizures. | PURPOSE: Neuropetide Y (NPY)-mediated neurotransmission in the hippocampus is altered by limbic seizures. The functional consequences of this change are still unresolved and clearly depend on the type of NPY receptors involved. NPY Y2 and Y1 receptors are increased on mossy fiber terminals and decreased on granule cell... | ['Animals', 'Anticonvulsants', 'Arginine', 'Blotting, Western', 'Electroencephalography', 'Epilepsy', 'Hippocampus', 'Injections, Intraventricular', 'Kainic Acid', 'Kindling, Neurologic', 'Limbic System', 'Male', 'Neuronal Plasticity', 'Pentylenetetrazole', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Neuropeptide Y'] | 10,999,532 | [['B01.050'], ['D27.505.954.427.080'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Understanding existing exposure situations. | International Commission on Radiological Protection (ICRP) Publication 103 removed the distinction between practices and interventions, and introduced three types of exposure situation: existing, planned, and emergency. It also emphasised the optimisation principle in connection with individual dose restrictions for al... | ['Humans', 'International Agencies', 'Radiation Dosage', 'Radiation Exposure', 'Radiation Monitoring', 'Radiation Protection'] | 26,975,365 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.540.514'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['G01.750.748', 'N06.850.460.350.850'], ['E05.799.638', 'N06.850.780.375.700', 'N06.850.810.370'], ['N06.850.810.425']] | ['Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Scopolamine sublingual spray: an alternative route of delivery for the treatment of motion sickness. | The purpose of this study was to develop a sublingual drug delivery spray formulation of scopolamine hydrobromide (L-(-)-hyoscine hydrobromide) and to determine the absolute bioavailability of scopolamine hydrobromide following sublingual delivery and to investigate the effect of a bioadhesive on the pharmacokinetic pa... | ['Adhesives', 'Administration, Sublingual', 'Animals', 'Area Under Curve', 'Biological Availability', 'Chitosan', 'Chromatography, Liquid', 'Excipients', 'Injections, Intravenous', 'Male', 'Mass Spectrometry', 'Motion Sickness', 'Muscarinic Antagonists', 'Rabbits', 'Scopolamine'] | 17,520,450 | [['D27.720.013', 'J01.637.016'], ['E02.319.267.100.878'], ['B01.050'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['G03.787.151', 'G07.690.725.129'], ['D05.750.078.139.500', 'D09.698.211.500'], ['E05.196.181.400'], ['D26.650.700.419', 'D27.720.744.770.419'], ['E02.319.267.082.750', 'E... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
DNA cleavage at two recognition sites by the SfiI restriction endonuclease: salt dependence of cis and trans interactions between distant DNA sites. | At low ionic strength, the SfiI restriction enzyme cleaved at similar rates both supercoiled and linear DNA with two SfiI sites and linear DNA with one SfiI site. For the substrates with two sites, the majority of the DNA was converted directly to products cut at both sites; the enzyme appears to bind to two sites befo... | ['Base Sequence', 'DNA', 'DNA, Superhelical', 'Deoxyribonucleases, Type II Site-Specific', 'Kinetics', 'Molecular Sequence Data', 'Osmolar Concentration', 'Plasmids', 'Sodium Chloride', 'Substrate Specificity'] | 7,563,060 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308'], ['D13.444.308.283.250', 'G02.111.570.820.486.212.250', 'G05.360.580.156.250'], ['D08.811.150.280.260', 'D08.811.277.352.335.350.300.260', 'D08.811.277.352.355.325.300.260'], ['G01.374.661', 'G02.111.490'], ['L01.453.245.667'], ['G02.640'], ['G... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Verbal fluency in mania: relationship to number of manic episodes. | OBJECTIVE: The objective of this study was to examine verbal fluency in a group of patients with bipolar disorder (BPD) during an acute episode of mania, and to determine whether performance was related to disease chronicity. We hypothesized that manic patients with BPD would be impaired on verbal fluency, and that thi... | ['Adult', 'Bipolar Disorder', 'Cognition Disorders', 'Female', 'Humans', 'Language Disorders', 'Language Tests', 'Male', 'Neuropsychological Tests', 'Severity of Illness Index', 'Verbal Behavior'] | 11,513,101 | [['M01.060.116'], ['F03.084.500'], ['F03.615.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.500', 'C23.888.592.604.150.500'], ['F04.711.513.240'], ['F04.711.513'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980.438.475.364.500'], ['F01.145.209.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Procoagulant effects of lung cancer chemotherapy: impact on microparticles and cell-free DNA. | Lung cancer is the second leading type of cancer, with venous thromboembolism being the second leading cause of death. Studies have shown increased levels of microparticles and cell-free DNA (CFDNA) in cancer patients, which can activate coagulation through extrinsic and intrinsic pathways, respectively. However, the i... | ['Animals', 'Cell-Derived Microparticles', 'DNA', 'Humans', 'Lung Neoplasms', 'Mice', 'Venous Thromboembolism'] | 26,919,453 | [['B01.050'], ['A11.284.295.588.500'], ['D13.444.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['B01.050.150.900.649.313.992.635.505.500'], ['C14.907.355.590.700']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulation of miR163 and its targets in defense against Pseudomonas syringae in Arabidopsis thaliana. | Small RNAs are important regulators for a variety of biological processes, including leaf development, flowering-time, embryogenesis and defense responses. miR163 is a non-conserved miRNA and its locus has evolved recently through inverted duplication of its target genes to which they belong to the SABATH family of rel... | ['Arabidopsis', 'Arabidopsis Proteins', 'Disease Resistance', 'Gene Expression Regulation, Plant', 'Host-Pathogen Interactions', 'MicroRNAs', 'Plant Diseases', 'Plants, Genetically Modified', 'Pseudomonas syringae'] | 28,401,908 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['C23.550.291.671', 'G12.450.564.250', 'G12.450.800.250', 'G15.630.250'], ['G05.308.375'], ['G06.462', 'G16.527.200'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['G15.610'], ['B01.650.520', 'B05.620.600'], ['B03.440.400.425.625.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term stability of surgical open-bite correction by Le Fort I osteotomy. | Skeletal changes greater than those observed in untreated adults have been noted beyond 1 year post-surgery in adult patients who had surgical correction of a long face deformity. The stability of skeletal landmarks and dental relationships from 1 to >3 years post-surgery was examined in 28 patients who had undergone s... | ['Adaptation, Physiological', 'Adult', 'Cephalometry', 'Chin', 'Facial Bones', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Malocclusion', 'Mandibular Advancement', 'Maxillofacial Abnormalities', 'Maxillofacial Development', 'Osteotomy, Le Fort', 'Recurrence', 'Syndrome', 'Tooth Eruption', 'Treatment Outcome'] | 10,832,998 | [['G07.025', 'G16.012.500'], ['M01.060.116'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['A01.456.505.259', 'A02.835.232.781.324.502.632.130', 'A14.521.632.300'], ['A02.835.232.781.324'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.90... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Open reduction of developmental hip dysplasia using a medial approach: a review of 24 hips. | The results of the Ferguson medial approach for reduction of developmental hip dysplasia were reviewed for 24 hips. The mean age at surgery was 4.8 months and the mean length of clinical follow-up was 59 months. Clinically all hips were normal in follow-up and radiologically the acetabular index was within normal limit... | ['Female', 'Follow-Up Studies', 'Hip Dislocation, Congenital', 'Humans', 'Infant', 'Male', 'Orthopedic Procedures', 'Reoperation'] | 18,686,459 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C05.660.297.500', 'C16.131.621.297.500', 'C16.131.621.449'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.718', 'E04.555'], ['E04.690']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Social, not individual, identification is the key to understanding group phenomena. | Baumeister and colleagues argue for the indispensability of groups in human life. Yet, in positing individual differentiation as the key to effective group functioning, they adopt a Western-centric view of the relationship of the individual to the group and overlook an alternative social identity account in which deper... | ['Humans', 'Individuation', 'Social Identification'] | 28,355,781 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.747.466'], ['F01.145.813.708']] | ['Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metabolic syndrome increases the prevalence of spine osteoarthritis. | OBJECTIVE: To determine whether the prevalence of severe spinal osteoarthritis (OA) increases with the number of metabolic syndrome (MetS) risk factors.METHODS: Data from a single surgeon's high volume, spine surgery practice were reviewed. Severe OA was defined as degenerative spondylolisthesis or cervical or lumbar s... | ['Body Mass Index', 'Case-Control Studies', 'Female', 'Humans', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Obesity', 'Osteoarthritis, Spine', 'Retrospective Studies', 'Risk Factors'] | 24,590,989 | [['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968.500.570', 'C18.452.625'], ['M01.060.116.630'], ['C18.654.726.500', 'C23.888.144... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Three channels of corticothalamic communication during locomotion. | We studied the flow of corticothalamic (CT) information from the motor cortex of the cat during two types of locomotion: visually guided (cortex dependent) and unguided. Spike trains of CT neurons in layers V (CT5s) and VI (CT6s) were examined. All CT5s had fast-conducting axons (<2 ms conduction time), and nearly all ... | ['Algorithms', 'Animals', 'Cats', 'Cerebral Cortex', 'Electric Conductivity', 'Electric Stimulation', 'Forelimb', 'Locomotion', 'Models, Animal', 'Neural Pathways', 'Neurons', 'Reinforcement, Psychology', 'Thalamus', 'Wakefulness'] | 15,976,080 | [['G17.035', 'L01.224.050'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.186.211.200.885.287.500'], ['G01.358.500.249.277'], ['E05.723.402'], ['A13.395'], ['G07.568.500', 'G11.427.410.568'], ['E05.598'], ['A08.612'], ['A08.675', 'A11.671'], ['F02.463.425.770'], ['A08.186.211.200.317.826'], ['F02... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Phosphoglyceride crystal deposition disease. | An extremely rare phosphoglyceride deposition disease is reported. A healthy 62-year-old Japanese woman suffered from tumors that repeatedly appeared in injured soft tissues for more than 20 years. No immunologic disorders or abnormal laboratory data were found. Histology showed foreign body granulomas consisting of ma... | ['Connective Tissue', 'Crystallization', 'Female', 'Glycerophospholipids', 'Granuloma, Foreign-Body', 'Humans', 'Macrophages', 'Mass Spectrometry', 'Microscopy, Electron', 'Middle Aged', 'Spectrophotometry, Infrared'] | 11,123,768 | [['A10.165'], ['E05.196.300', 'G02.171'], ['D10.570.755.375.760.400'], ['C23.550.382.437', 'C26.392.560.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['E05.196.566'], ['E01.370.350.515.402', 'E05.595.402'], ['M01.060.116.630'... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cortical thickness is influenced by regionally specific genetic factors. | BACKGROUND: Although global brain structure is highly heritable, there is still variability in the magnitude of genetic influences on the size of specific regions. Yet, little is known about the patterning of those genetic influences, i.e., whether the same genes influence structure throughout the brain or whether ther... | ['Adult', 'Cerebral Cortex', 'Female', 'Genetic Variation', 'Genotype', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Phenotype', 'Twins'] | 19,963,208 | [['M01.060.116'], ['A08.186.211.200.885.287.500'], ['G05.365'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['G05.695'], ['M01.438.873']] | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A benchmark study on error-correction by read-pairing and tag-clustering in amplicon-based deep sequencing. | BACKGROUND: The high error rate of next generation sequencing (NGS) restricts some of its applications, such as monitoring virus mutations and detecting rare mutations in tumors. There are two commonly employed sequencing library preparation strategies to improve sequencing accuracy by correcting sequencing errors: rea... | ['High-Throughput Nucleotide Sequencing', 'Reproducibility of Results', 'Sequence Analysis, DNA'] | 26,868,371 | [['E05.393.760.319'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.393.760.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The tissue reactions of mice to infection with Heligmosmoides polygyrus. | The intestines of normal and resistant LAF1 mice were subjected to histologic study to determine the timing and mechanisms of resistance to reinfection by Heligmosmoides polygyrus. During reinfection third-stage larvae are less able to penetrate the intestinal wall. Larvae which are able to encyst develop at a slower r... | ['Animals', 'Female', 'Immunity, Innate', 'Inflammation', 'Intestines', 'Larva', 'Lung', 'Mice', 'Mice, Inbred AKR', 'Mice, Inbred BALB C', 'Nematode Infections', 'Nematospiroides dubius'] | 3,372,983 | [['B01.050'], ['G12.450.564'], ['C23.550.470'], ['A03.556.124'], ['B05.500.500', 'G07.345.500.550.500.500'], ['A04.411'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.318', 'B01.050.150.900.649.313.992.635.505.500.400.318'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
WhatSAP - 2B4 sends mixed messages in the absence of SAP. | 2B4 (CD244), a member of the SLAM-related receptor family, has important immuno-regulatory functions including coactivating the cytotoxicity and cytokine secretion of NK cells. Immune modulation by 2B4 is dependent on the small intracellular signaling molecule SAP. In patients suffering from X-linked lymphoproliferativ... | ['Animals', 'Antigens, CD', 'Antigens, Differentiation, T-Lymphocyte', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Killer Cells, Natural', 'Lymphocyte Activation', 'Lymphoproliferative Disorders', 'NK Cell Lectin-Like Receptor Subfamily K', 'Receptors, Immunologic', 'Signal Transduction', 'Signaling Lym... | 24,659,462 | [['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.894', 'D23.101.100.894'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360', 'D12.776.476'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.47... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Program closure and change among VA substance abuse treatment programs. | OBJECTIVE: The population of Veterans Affairs (VA) substance abuse treatment programs in 1990 and 1994 was examined to determine which factors-program legitimacy or cost-accounted for program closure and change. Legitimacy is a concept in institutional theory that organizations tend to take on a form appropriate to the... | ['Health Facility Closure', 'Health Personnel', 'Humans', 'Mental Health Services', 'Retrospective Studies', 'Substance-Related Disorders', 'United States', 'United States Department of Veterans Affairs'] | 10,506,300 | [['N02.278.218', 'N05.300.430.390'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.408', 'N02.421.461'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825']... | ['Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A NASBA method to detect high- and low-pathogenicity H5 avian influenza viruses. | Nucleic acid sequence-based amplification (NASBA) allows the rapid amplification of specific regions of nucleic acid obtained from a diverse range of sources. It is especially suitable for amplifying RNA sequences. A NASBA technique was developed that allows the detection of avian influenza A subtype H5 from allantoic ... | ['Allantois', 'Animals', 'Base Sequence', 'Birds', 'Chick Embryo', 'DNA Primers', 'Influenza A virus', 'Influenza in Birds', 'RNA, Viral', 'Self-Sustained Sequence Replication', 'Sensitivity and Specificity'] | 14,575,113 | [['A10.615.284.147', 'A16.254.750.147'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.248'], ['A13.350.150', 'A16.331.200'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B04.820.480.968.405.400'], ['C01.925.782.620.300', 'C22.131.450'], ['D13.444.735.828'], ... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Mechanisms of increased NGF production in vascular smooth muscle of the spontaneously hypertensive rat. | The spontaneously hypertensive rat (SHR) was developed as a genetic model of essential hypertension. In vivo and in vitro evidence demonstrates that vascular smooth muscle cells (VSMCs) from the SHR produce more nerve growth factor (NGF) than the normotensive Wistar-Kyoto (WKY) control strain. This increased NGF produc... | ['Animals', 'Cells, Cultured', 'Culture Media, Serum-Free', 'Dactinomycin', 'Muscle, Smooth', 'Muscle, Smooth, Vascular', 'Mutation', 'Nerve Growth Factors', 'Nucleic Acid Synthesis Inhibitors', 'Platelet-Derived Growth Factor', 'Polymerase Chain Reaction', 'Protein Biosynthesis', 'RNA, Messenger', 'Rats', 'Rats, Inbre... | 9,633,527 | [['B01.050'], ['A11.251'], ['D27.720.470.305.255', 'E07.206.255'], ['D03.633.300.200', 'D04.345.566.252', 'D12.644.641.252'], ['A02.633.570', 'A10.690.467'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['G05.365.590'], ['D12.644.276.860', 'D12.776.467.860', 'D12.776.631.600', 'D23.529.850'], ['D27.505.51... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Monitoring winter and summer abundance of cetaceans in the Pelagos Sanctuary (northwestern Mediterranean Sea) through aerial surveys. | Systematic long-term monitoring of abundance is essential to inform conservation measures and evaluate their effectiveness. To instigate such work in the Pelagos Sanctuary in the Mediterranean, two aerial surveys were conducted in winter and summer 2009. A total of 467 (131 in winter, 336 in summer) sightings of 7 spec... | ['Animals', 'Conservation of Natural Resources', 'Data Collection', 'Environmental Monitoring', 'Fin Whale', 'Mediterranean Sea', 'Population Density', 'Seasons', 'Stenella'] | 21,829,544 | [['B01.050'], ['J01.256', 'N06.230.080'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.649.313.875.865.100.350'], ['Z01.756.592'], ['N01.224.600', 'N06.850.505.400.600'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.25... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
Stability of elastin in the developing mouse aorta: a quantitative radioautographic study. | Elastic lamina growth during development and the ultimate stability of elastin in the mouse aortic media was investigated by light and electron microscopic radioautography. Following a single subcutaneous injection of L-[3,4-3H]valine at 3 days of age, animals were killed at 9 subsequent time intervals up to 4 months o... | ['Aging', 'Animals', 'Aorta', 'Autoradiography', 'Drug Stability', 'Elastin', 'Light', 'Mice', 'Mice, Inbred C57BL', 'Microscopy', 'Microscopy, Electron', 'Muscle, Smooth, Vascular', 'Tritium', 'Valine'] | 8,226,106 | [['G07.345.124'], ['B01.050'], ['A07.015.114.056'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['E05.916.330'], ['D05.750.078.421', 'D12.776.860.300.350'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Takayasu's arteritis and its therapy. | Twenty patients with Takayasu's arteritis were followed prospectively for an average of 4.6 years. Sixteen patients with active inflammatory Takayasu's arteritis were treated with glucocorticosteroids; eight responded to therapy. Six patients had clinical or angiographic progression of their vasculitis on daily cortico... | ['Adolescent', 'Adult', 'Aortic Arch Syndromes', 'Arteritis', 'Child', 'Combined Modality Therapy', 'Cyclophosphamide', 'Drug Therapy, Combination', 'Female', 'Humans', 'Middle Aged', 'Prednisone', 'Prospective Studies', 'Takayasu Arteritis'] | 2,860,834 | [['M01.060.057'], ['M01.060.116'], ['C14.907.109.239'], ['C14.907.940.090'], ['M01.060.406'], ['E02.186'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D04.210.500.745.432.719.702'], ['E05.318.372.500.750.625', 'N05.715.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Direct Dynamic Kinetic Analysis and Computer Simulation of Growth of Clostridium perfringens in Cooked Turkey during Cooling. | This research applied a new 1-step methodology to directly construct a tertiary model that describes the growth of Clostridium perfringens in cooked turkey meat under dynamically cooling conditions. The kinetic parameters of the growth models were determined by numerical analysis and optimization using multiple dynamic... | ['Animals', 'Clostridium perfringens', 'Colony Count, Microbial', 'Computer Simulation', 'Cooking', 'Food Handling', 'Food Microbiology', 'Food-Processing Industry', 'Humans', 'Kinetics', 'Meat', 'Models, Biological', 'Temperature', 'Turkeys'] | 26,801,359 | [['B01.050'], ['B03.300.390.400.200.575', 'B03.353.625.375.500.575', 'B03.510.415.400.200.575'], ['E01.370.225.875.220', 'E05.200.875.220'], ['L01.224.160'], ['J01.576.423.200.200'], ['J01.576.423.200'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.60... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
[Method of evaluating the psychological conflict in patients who have had a myocardial infarct]. | A test for quantitative appraisal of psychological confliction is described. A variant of the "Polar personality profiles" method (SDF) is used as the basis of the test. The corresponding scheme for presenting the SDF and interpreting the data obtained is elaborated. Data obtained during clinical interrogations were us... | ['Conflict, Psychological', 'Humans', 'Interpersonal Relations', 'Myocardial Infarction', 'Personality Tests', 'Psychological Tests', 'Semantic Differential'] | 7,354,604 | [['F01.658.209'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['F04.711.647'], ['F04.711'], ['F02.694.663', 'F04.711.647.745']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Physical Fitness Among Swedish Military Conscripts and Long-Term Risk for Type 2 Diabetes Mellitus: A Cohort Study. | BACKGROUND: Early-life physical fitness has rarely been examined in relation to type 2 diabetes mellitus (DM) in adulthood because of the lengthy follow-up required. Elucidation of modifiable risk factors at young ages may help facilitate earlier and more effective interventions.OBJECTIVE: To examine aerobic capacity a... | ['Adolescent', 'Adult', 'Body Mass Index', 'Diabetes Mellitus, Type 2', 'Exercise Test', 'Follow-Up Studies', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Military Personnel', 'Muscle Strength', 'Oxygen Consumption', 'Physical Fitness', 'Risk Factors', 'Socioeconomic Factors', 'Sweden'] | 26,954,518 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C18.452.394.750.149', 'C19.246.300'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Recombinant tissue plasminogen activator for minor strokes: the National Institute of Neurological Disorders and Stroke rt-PA Stroke Study experience. | STUDY OBJECTIVE: Acute ischemic stroke patients eligible for tissue plasminogen activator and with less severe neurologic deficits, although still generally benefiting from therapy, may have a different risk-benefit profile than all eligible acute stroke patients. We address whether patients with a minor stroke should ... | ['Confidence Intervals', 'Double-Blind Method', 'Fibrinolytic Agents', 'Hospitalization', 'Humans', 'Odds Ratio', 'Outcome and Process Assessment, Health Care', 'Stroke', 'Tissue Plasminogen Activator', 'Treatment Outcome'] | 16,126,134 | [['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Quantitative T1 Mapping for Detecting Microvascular Obstruction in Reperfused Acute Myocardial Infarction: Comparison with Late Gadolinium Enhancement Imaging. | OBJECTIVE: To compare native and post-contrast T1 mapping with late gadolinium enhancement (LGE) imaging for detecting and measuring the microvascular obstruction (MVO) area in reperfused acute myocardial infarction (MI).MATERIALS AND METHODS: This study included 20 patients with acute MI who had undergone 1.5T cardiov... | ['Adult', 'Contrast Media', 'Female', 'Gadolinium', 'Heart', 'Humans', 'Image Enhancement', 'Magnetic Resonance Imaging, Cine', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Myocardial Reperfusion Injury', 'Myocardium'] | 32,677,382 | [['M01.060.116'], ['D27.505.259.500', 'D27.720.259'], ['D01.268.558.362.484', 'D01.552.550.399.484'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.370.350.825.500.510'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Functional Status Is Associated With 30-Day Potentially Preventable Readmissions Following Skilled Nursing Facility Discharge Among Medicare Beneficiaries. | OBJECTIVES: The objectives of this study were to determine the association between patients' functional status at discharge from skilled nursing facility (SNF) care and 30-day potentially preventable hospital readmissions, and to examine common reasons for potentially preventable readmissions.DESIGN: Retrospective coho... | ['Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Geriatric Assessment', 'Humans', 'Male', 'Medicare', 'Odds Ratio', 'Patient Discharge', 'Patient Readmission', 'Physical Fitness', 'Retrospective Studies', 'Risk Assessment', 'Skilled Nursing Facilities', 'Texa... | 29,371,127 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.318.308.225', 'I01.240.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Medial lower lid epiblepharon repair solely by skin-redraping medial epicanthoplasty. | BACKGROUND/AIMS: To evaluate clinical efficacy of a procedure using solely skin-redraping medial epicanthoplasty without traditional epiblepharon correction methods in patients with medial lower lid epiblepharon with epicanthal fold.METHODS: This clinical practice study included 24 eyes of 12 patients with medial lower... | ['Adolescent', 'Blepharoplasty', 'Child', 'Child, Preschool', 'Dermatologic Surgical Procedures', 'Eyelid Diseases', 'Eyelids', 'Female', 'Humans', 'Male', 'Surgical Flaps', 'Treatment Outcome'] | 24,855,116 | [['M01.060.057'], ['E04.540.104', 'E04.680.275.090'], ['M01.060.406'], ['M01.060.406.448'], ['E04.680.275'], ['C11.338'], ['A01.456.505.420.504', 'A09.371.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.850.710', 'E07.862.710'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The requirement for surface Ig signaling as a prerequisite for T cell:B cell interactions. A possible role for desialylation. | Models for T cell:B cell collaboration suggest that activated B cells process and present Ag to Th cells which subsequently induce B cell proliferation and differentiation. In contrast to activated B cells, resting B cells have generally been shown to be less efficient APC. If this model of T:B collaboration is physiol... | ['Animals', 'Antibodies, Anti-Idiotypic', 'Antigen-Presenting Cells', 'Antigens, Surface', 'B-Lymphocytes', 'Cell Aggregation', 'Female', 'Immunoglobulin mu-Chains', 'Lymphocyte Activation', 'Lymphocyte Cooperation', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred DBA', 'N-Acetylneuraminic Acid', 'Neuraminidase', 'Receptor... | 3,126,236 | [['B01.050'], ['D12.776.124.486.485.114.071', 'D12.776.124.790.651.114.071', 'D12.776.377.715.548.114.071'], ['A11.066', 'A15.382.066'], ['D23.050.301'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G04.198.251'], ['D12.776.124.486.485.114.61... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oral Administration of Polymyxin B Modulates the Activity of Lipooligosaccharide E. coli B against Lung Metastases in Murine Tumor Models. | INTRODUCTION: Polymyxin B (PmB) belongs to the group of cyclic peptide antibiotics, which neutralize the activity of LPS by binding to lipid A. The aim of this study was to analyze the effect of PmB on the biological activity of lipooligosaccharide (LOS E. coli B,rough form of LPS) in vitro and in experimental metastas... | ['Administration, Oral', 'Animals', 'Carcinoma, Lewis Lung', 'Concanavalin A', 'Cytokines', 'Dendritic Cells', 'Disease Models, Animal', 'Escherichia coli', 'Female', 'Injections, Intravenous', 'Lipopolysaccharides', 'Lung', 'Lung Neoplasms', 'Lymphocytes', 'Macrophages, Peritoneal', 'Melanoma, Experimental', 'Mice, In... | 26,829,479 | [['E02.319.267.100'], ['B01.050'], ['C04.557.470.200.280', 'C04.619.230'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B03.440.450.425.325.300... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification and analysis of the site of -1 ribosomal frameshifting in red clover necrotic mosaic virus. | The genomic RNA-1 of red clover necrotic mosaic dianthovirus (RCNMV) contains the heptanucleotide GGAUUUU that precedes the termination codon of the 5' proximal p27 open reading frame (ORF). This heptanucleotide is followed by a sequence with the potential to form a stable, complex secondary structure. Translation of R... | ['Base Sequence', 'DNA Mutational Analysis', 'Fabaceae', 'Molecular Sequence Data', 'Mosaic Viruses', 'Mutagenesis, Site-Directed', 'Nucleic Acid Conformation', 'Oligoribonucleotides', 'Plants, Medicinal', 'Plants, Toxic', 'Protein Biosynthesis', 'Reading Frames', 'Regulatory Sequences, Nucleic Acid', 'Sequence Analysi... | 8,178,444 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.760.700.300'], ['B01.650.940.800.575.912.250.401'], ['L01.453.245.667'], ['B04.715.464'], ['E05.393.420.601.575'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.695.578.424.500'], ['B01.650.560'], ['B01.650.660'], ['G02.111.660.871', 'G03.734.871', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Off-pump versus on-pump coronary artery bypass grafting in patients with left ventricular dysfunction. | OBJECTIVE: Using data from the Japan Adult Cardiovascular Surgery Database, we evaluated the prognostic influence of off-pump technique in patients with low ejection fraction who underwent coronary artery bypass grafting.METHODS: We analyzed 2187 patients with an ejection fraction <0.30 who underwent primary, nonemerge... | ['Aged', 'Cardiopulmonary Bypass', 'Coronary Artery Bypass', 'Coronary Artery Bypass, Off-Pump', 'Coronary Artery Disease', 'Databases, Factual', 'Female', 'Humans', 'Japan', 'Logistic Models', 'Male', 'Middle Aged', 'Postoperative Complications', 'Propensity Score', 'Retrospective Studies', 'Risk Factors', 'Stroke Vol... | 26,725,715 | [['M01.060.116.100'], ['E04.292.413'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E04.100.376.719.332.199', 'E04.100.814.868.750.199', 'E04.928.220.520.220.189'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Stereo-controlled C-C bond formation at the anomeric position of uracil nucleosides. | Stereoselective synthesis of 1'-carbon-substituted uracil nucleosides has been achieved through face-selective bromo-pivaloyloxylation of a 1',2'-unsaturated derivative and successive SnCl4-promoted nucleophilic substitution with organosilicon reagents. This constitutes the first example of C-C bond formation at the an... | ['Carbon', 'Nucleosides', 'Organosilicon Compounds', 'Stereoisomerism', 'Uracil'] | 8,247,780 | [['D01.268.150'], ['D09.408.595', 'D13.570'], ['D02.756'], ['G02.607.445.682'], ['D03.383.742.698.875']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modulation of the effects of osteoprotegerin (OPG) ligand in a human leukemic cell line by OPG and calcitonin. | The discovery of osteoprotegerin (OPG), osteoprotegerin ligand (OPGL), and RANK has elucidated the mechanism by which osteoblasts and stromal cells regulate osteoclastic differentiation and function and mediate the effects exerted by other hormones and cytokines. We have investigated the effects of these novel cytokine... | ['Acid Phosphatase', 'Calcitonin', 'Carrier Proteins', 'Cell Adhesion', 'Cell Differentiation', 'Cell Division', 'Cell Survival', 'Cells, Cultured', 'Glycoproteins', 'Humans', 'Isoenzymes', 'Leukemia, Monocytic, Acute', 'Lymphocytes', 'Macrophage Colony-Stimulating Factor', 'Membrane Glycoproteins', 'Osteoclasts', 'Ost... | 11,118,297 | [['D08.811.277.352.650.025'], ['D06.472.699.150', 'D06.472.931.052', 'D12.644.400.095', 'D12.644.548.150', 'D12.776.631.650.095'], ['D12.776.157'], ['G04.022'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.346'], ['A11.251'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The variability of viability: the effect of physicians' perceptions of viability on the survival of very low--birth weight infants. | Physicians who deliver babies in Alabama were surveyed to determine their level of knowledge about the survival of low--birth weight/early gestational age infants. These estimates of neonatal survival were compared to the actual neonatal survival rates at local hospitals and at the regional perinatal centers in Alabama... | ['Adult', 'Cognition', 'Female', 'Georgia', 'Hospitals, Community', 'Humans', 'Infant Mortality', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Infant, Premature', 'Male', 'Middle Aged', 'Perception', 'Physicians', 'Pregnancy', 'Probability', 'Regional Medical Programs'] | 7,091,240 | [['M01.060.116'], ['F02.463.188'], ['Z01.107.567.875.075.250', 'Z01.107.567.875.750.370'], ['N02.278.421.306'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.550.475', 'N01.224.935.698.489', 'N06.850.505.400.975.550.475', 'N06.850.520.308.985.550.475'], ['M01.060.703.520.460'], ['M01.060.703.520'],... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hindsight bias in reflective practice: an empirical investigation. | Reflection is seen as a central component in the education and practice of nurses. It is through critical reflection on one's practice that expertise can be assured. This faith in the process of reflection has influenced much of pre and post registration nurse education. It is only in the past few years that reflection... | ['Bias', 'Humans', 'Mental Recall', 'Nurses', 'Nursing Diagnosis', 'Psychometrics', 'United Kingdom'] | 7,797,718 | [['N05.715.350.150', 'N06.850.490.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['M01.526.485.650', 'N02.360.650'], ['N04.590.233.508.480.110'], ['F04.711.780'], ['Z01.542.363']] | ['Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Does the diagnosis of trachoma adequately identify ocular chlamydial infection in trachoma-endemic areas? | We evaluated the validity of clinically determined active trachoma as a surrogate for chlamydial eye infection in 1059 children from the Egyptian arm of the Azithromycin in the Control of Trachoma study. Participants were determined to be "clinically active" if they had >or=5 follicles or intense inflammatory infiltrat... | ['Adolescent', 'Age Factors', 'Anti-Bacterial Agents', 'Azithromycin', 'Child', 'Child, Preschool', 'Chlamydia trachomatis', 'Egypt', 'Humans', 'Infant', 'Tetracycline', 'Trachoma'] | 12,721,948 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['D27.505.954.122.085'], ['D02.540.576.500.992.050'], ['M01.060.406'], ['M01.060.406.448'], ['B03.440.190.190.190.750'], ['Z01.058.266.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D02.455.426.559.847.562.900.875', 'D04.615.562.900.8... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Fibrinogen ã' levels in patients with intracerebral hemorrhage. | BACKGROUND: The fibrinogen ã' variant (ã') has both antithrombotic and prothrombotic properties when compared to normal fibrinogen. It may therefore be of relevance in intracerebral hemorrhage and intraventricular extension of the bleeding.OBJECTIVE: To study the role of ã' in intracerebral hemorrhage, and in intravent... | ['Case-Control Studies', 'Cerebral Hemorrhage', 'Female', 'Fibrinogen', 'Fibrinogens, Abnormal', 'Humans', 'Male', 'Middle Aged', 'Risk Factors'] | 21,917,300 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['D12.776.124.050.250.265', 'D12.776.124.125.500.265', 'D23.119.490.265'], ['B01.05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Alternative treatment strategies to accelerate the elimination of onchocerciasis. | The use of alternative (or complementary) treatment strategies (ATSs) i.e. differing from annual community-directed treatment with ivermectin (CDTI) is required in some African foci to eliminate onchocerciasis by 2025. ATSs include vector control, biannual or pluriannual CDTI, better timing of CDTI, community-directed ... | ['Animals', 'Anthelmintics', 'Disease Eradication', 'Humans', 'Insect Control', 'Ivermectin', 'Onchocerca volvulus', 'Onchocerciasis', 'Prevalence'] | 29,471,342 | [['B01.050'], ['D27.505.954.122.250.075'], ['N06.850.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.780.200.650.425'], ['D02.540.576.500.997'], ['B01.050.500.500.294.400.937.463.510.850'], ['C01.610.335.508.700.750.361.699', 'C01.610.858.650', 'C17.800.838.775.690'], ['E05.318.308.985.525.750', 'N01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Solubility enhancement of hydrophobic compounds by cosolvents: role of solute hydrophobicity on the solubilization effect. | Drug solubilization is an important aspect of drug development. We investigate the relationship between solute hydrophobicity on the solubilization properties of water-cosolvent mixtures. The solubilization in water-cosolvent mixtures of seven chemically unrelated drugs was determined. The set of solutes included hydro... | ['1-Propanol', 'Chemistry, Pharmaceutical', 'Drug Compounding', 'Ethanol', 'Glycerides', 'Hydrophobic and Hydrophilic Interactions', 'Linear Models', 'Methanol', 'Models, Chemical', 'Organic Chemicals', 'Pharmaceutical Preparations', 'Polyethylene Glycols', 'Pyrrolidinones', 'Solubility', 'Solvents', 'Technology, Pharm... | 20,363,302 | [['D02.033.755.600'], ['H01.158.703.007', 'H01.181.466'], ['E05.916.270'], ['D02.033.375'], ['D10.351'], ['G02.409'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['D02.033.623'], ['E05.599.... | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Cholesterol granuloma of the maxillary sinus. | INTRODUCTION: Cholesterol granuloma (CG) can be found in several areas of the body. Maxillary sinus localization is considered rare.CASE REPORT: A 37-year-old male presented with acute febrile sinusitis. Nasal endoscopy showed a nasal polyp at the middle meatus. Computed Tomography (CT scan) of the sinus showed complet... | ['Adult', 'Cholesterol', 'Granuloma, Foreign-Body', 'Humans', 'Male', 'Maxillary Sinus', 'Paranasal Sinus Diseases', 'Tomography, X-Ray Computed'] | 21,866,747 | [['M01.060.116'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['C23.550.382.437', 'C26.392.560.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.531.621.578'], ['C08.460.692', 'C09.603.692'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Analysis of autofluorescence pattern in birdshot chorioretinopathy. | PURPOSE: To characterize and correlate the different patterns of fundus autofluorescence (FAF) in patients with birdshot chorioretinopathy (BSCR), with functional and anatomical parameters.METHODS: Twenty-one BSCR patients were prospectively studied in 2013 and 2014. Each patient underwent visual acuity (VA) and visual... | ['Birdshot Chorioretinopathy', 'Chorioretinitis', 'Choroid', 'Female', 'Fluorescein Angiography', 'Fundus Oculi', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Retina', 'Tomography, Optical Coherence', 'Visual Acuity', 'Visual Fields'] | 28,451,757 | [['C11.768.773.348.500', 'C11.941.160.478.400.500', 'C11.941.879.780.900.300.318.500', 'C11.941.879.780.900.650.250', 'C20.111.303'], ['C11.768.773.348', 'C11.941.160.478.400', 'C11.941.879.780.900.300.318'], ['A09.371.894.223'], ['E01.370.370.050.350', 'E01.370.380.250'], ['A09.371.729.313'], ['B01.050.150.900.649.313... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Assessing farmers' perspectives on climate change for effective farm-level adaptation measures in Khyber Pakhtunkhwa, Pakistan. | Agriculture is considered as the backbone of the economy of Pakistan. However, current changes in climate have been adversely affecting agricultural productivity. In this paper, perceived impacts of climate change on agriculture and adaptation towards it have been studied in Charsadda district (lowlands) of Khyber Pakh... | ['Agriculture', 'Climate Change', 'Crops, Agricultural', 'Droughts', 'Environmental Monitoring', 'Farmers', 'Farms', 'Fertilizers', 'Floods', 'Humans', 'Male', 'Pakistan', 'Public Opinion'] | 31,392,429 | [['J01.040'], ['G16.500.175.374'], ['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['G16.500.175.781', 'G16.500.750.775.154', 'N06.230.100.230.150'], ['N06.850.460.350.080', 'N06.850.780.375'], ['M01.526.390'], ['J01.040.372', 'J03.540.150'], ['D27.720.031.400'], ['G16.500.175.812', 'N06.230.100.230.250'], ['B01.050... | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Molecular cloning and characterization of groESL operon in Streptococcus pneumoniae. | GroEL is a major target of the immune defense in infection and seems to be negatively regulated by HrcA in gram-positive organisms. However, HrcA's mechanism has not been elucidated. To elucidate the role of groEL in Streptococcus pneumoniae, the groESL operon was cloned in Escherichia coli. The promoter region of the ... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Base Sequence', 'Chaperonins', 'Cloning, Molecular', 'DNA-Binding Proteins', 'Escherichia coli Proteins', 'Gene Expression Regulation, Bacterial', 'HSP70 Heat-Shock Proteins', 'Molecular Sequence Data', 'Operon', 'Promoter Regions, Genetic', 'RNA, Messenger', 'Repetitive S... | 11,459,227 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.277.040.025.142', 'D12.776.580.216.210'], ['E05.393.220'], ['D12.776.260'], ['D12.776.097.275'], ['G05.308.300'], ['D12.776.580.216.375'], ['L01.453.245.667'], ['G05.360.340.024.686', 'G05.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Flexible endoscopic evaluation of swallowing with sensory testing in patients with unilateral vocal fold immobility: incidence and pathophysiology of aspiration. | OBJECTIVES/HYPOTHESIS: The objective was to examine the incidence and pathophysiology of aspiration in patients with unilateral vocal fold immobility presenting with dysphagia.STUDY DESIGN: Retrospective review of flexible endoscopic evaluation of swallowing with sensory testing (FEESST) data and medical records in two... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Deglutition', 'Deglutition Disorders', 'Edema', 'Erythema', 'Female', 'Gagging', 'Humans', 'Inhalation', 'Laryngeal Diseases', 'Laryngoscopy', 'Larynx', 'Male', 'Middle Aged', 'Pharynx', 'Reflex, Abnormal', 'Retrospective Studies', 'Sensation', 'Se... | 15,805,859 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G10.261.178'], ['C06.405.117.119', 'C09.775.174'], ['C23.888.277'], ['C17.800.229', 'C23.888.885.328'], ['C23.888.821.414', 'F02.830.702.157', 'G10.261.338', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An Epstein-Barr virus-encoded microRNA targets PUMA to promote host cell survival. | Epstein-Barr virus (EBV) is a herpesvirus associated with nasopharyngeal carcinoma (NPC), gastric carcinoma (GC), and other malignancies. EBV is the first human virus found to express microRNAs (miRNAs), the functions of which remain largely unknown. We report on the regulation of a cellular protein named p53 up-regula... | ['Apoptosis', 'Apoptosis Regulatory Proteins', 'Blotting, Western', 'Cell Line', 'Cell Survival', 'Computational Biology', 'DNA Primers', 'Gene Expression Regulation', 'Herpesvirus 4, Human', 'Humans', 'In Situ Nick-End Labeling', 'MicroRNAs', 'Plasmids', 'Proto-Oncogene Proteins'] | 18,838,543 | [['G04.146.954.035'], ['D12.644.360.075', 'D12.776.476.075'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210'], ['G04.346'], ['H01.158.273.180', 'L01.313.124'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.308'], ['B04.280.210.400.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Evaluation of genotoxic and apoptotic potential of Hypericum adenotrichum Spach. in vitro. | Hypericum adenotrichum Spach. is an endemic plant from Turkey that is also used in folk medicine. In this study, following analyses of its chemical composition, the genotoxic/antigenotoxic effects of the methanol extract of H. adenotrichum in human lymphocyte culture were investigated using in vitro sister chromatid ex... | ['Adenosine Triphosphate', 'Adolescent', 'Adult', 'Antineoplastic Agents, Phytogenic', 'Apoptosis', 'Breast Neoplasms', 'Cell Proliferation', 'Cell Survival', 'Comet Assay', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Hypericum', 'Lymphocytes', 'MCF-7 Cells', 'Male', 'Micronuclei, Chromosome-Defective', 'M... | 26,617,407 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['M01.060.057'], ['M01.060.116'], ['D27.505.954.248.179'], ['G04.146.954.035'], ['C04.588.180', 'C17.800.090.500'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Short-term outcomes of minimally invasive Sweet esophagectomy for Siewert type ? esophagogastric junction adenocarcinoma]. | Objective: To describe the technique for minimally invasive Sweet esophagectomy and to evaluate the feasibility, safety and the short-term clinical outcomes of this approach in the treatment of Siewert type ? esophagogastric junction adenocarcinoma. Methods: The clinical data of 122 patients with Siewert type ? esophag... | ['Adenocarcinoma', 'Aged', 'Blood Loss, Surgical', 'Esophageal Neoplasms', 'Esophagectomy', 'Esophagogastric Junction', 'Female', 'Hospital Mortality', 'Humans', 'Lymph Node Excision', 'Lymph Nodes', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Minimally Invasive Surgical Procedures', 'Neoplasm Staging', 'Postoperat... | 27,938,582 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['C23.550.414.300', 'C23.550.505.300'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E04.210.346'], ['A03.556.875.500.414', 'A03.556.875.875.330'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Indirect methods for improving parameter estimation of PET kinetic models. | PURPOSE: Parametric images obtained from kinetic modeling of dynamic positron emission tomography (PET) data provide a new way of visualizing quantitative parameters of the tracer kinetics. However, due to the high noise level in pixel-wise image-driven time-activity curves, parametric images often suffer from poor qua... | ['Algorithms', 'Brain', 'Computer Simulation', 'Humans', 'Image Processing, Computer-Assisted', 'Kinetics', 'Models, Theoretical', 'Phantoms, Imaging', 'Positron-Emission Tomography', 'Signal-To-Noise Ratio'] | 30,762,875 | [['G17.035', 'L01.224.050'], ['A08.186.211'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['G01.374.661', 'G02.111.490'], ['E05.599'], ['E07.671'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399', 'E01.370.350.710.800.399', 'E01.370.350.825.800.399', 'E01.370.384.730.800... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Impact of Changing Treatment Strategies on Outcomes in Pediatric Ulcerative Colitis. | BACKGROUND: In recent years, treatment strategies for ulcerative colitis have evolved with an early step-up approach, the availability of biologicals, and therapeutic drug monitoring.We carried out this study to evaluate the effect of these changes on disease outcomes.METHODS: In this retrospective review, 2 time perio... | ['Adolescent', 'Australia', 'Child', 'Child, Preschool', 'Colectomy', 'Colitis, Ulcerative', 'Female', 'Gastrointestinal Agents', 'Humans', 'Infliximab', 'Logistic Models', 'Male', 'Mesalamine', "Practice Patterns, Physicians'", 'Retrospective Studies', 'Treatment Outcome'] | 31,002,341 | [['M01.060.057'], ['Z01.639.100', 'Z01.678.100.373'], ['M01.060.406'], ['M01.060.406.448'], ['E04.210.219'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['D27.505.954.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.224.608', 'D12.77... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Breast cancer and atypia among young and middle-aged women: a study of 110 medicolegal autopsies. | In 110 consecutive, medicolegal autopsies of young and middle-aged women (range 20-54 years) the breasts were examined by an extensive histopathologic method and by correlative specimen radiography. Malignancy was found in 22 women (20%) of which only one was known to have had clinical invasive breast cancer (IBC). At ... | ['Adult', 'Alcoholism', 'Breast', 'Breast Diseases', 'Breast Neoplasms', 'Carcinoma in Situ', 'Carcinoma, Intraductal, Noninfiltrating', 'Denmark', 'Female', 'Humans', 'Hyperplasia', 'Liver Diseases, Alcoholic', 'Middle Aged'] | 2,829,956 | [['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['A01.236'], ['C17.800.090'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.240'], ['C04.557.470.200.025.275', 'C04.557.470.200.240.187.250', 'C04.557.470.615.275'], ['Z01.542.816.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], [... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Geographicals [Z]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
The equal effectiveness of different defensive strategies. | Plants have evolved a variety of defensive strategies to resist herbivory, but at the interspecific level, the relative effectiveness of these strategies has been poorly evaluated. In this study, we compared the level of herbivory between species that depend on ants as indirect defenders and species that rely primarily... | ['Animals', 'Ants', 'Biological Evolution', 'Herbivory', 'Phylogeny', 'Plant Physiological Phenomena', 'Plants', 'Species Specificity', 'Symbiosis'] | 26,267,426 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.205'], ['G05.045', 'G16.075'], ['F01.145.113.547.600', 'F01.145.407.758', 'G07.203.650.353.758'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G15'], ['B01.650'], ['G16.824'], ['G06.550.800', 'G16.840']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Randomized controlled trial of adjunctive Valproate for cognitive remediation in early course schizophrenia. | BACKGROUND: Schizophrenia (SZ) is associated with cognitive impairment that contributes to disability, but the cognitive dysfunction is relatively refractory to pharmacologic intervention. Though Valproate augmentation is reported to improve psychopathology among patients with SZ, its effects on cognitive functions hav... | ['Adolescent', 'Adult', 'Antimanic Agents', 'Antipsychotic Agents', 'Cognitive Dysfunction', 'Double-Blind Method', 'Drug Synergism', 'Drug Therapy, Combination', 'Humans', 'Middle Aged', 'Risperidone', 'Schizophrenia', 'Toxoplasmosis', 'Treatment Outcome', 'Valproic Acid', 'Young Adult'] | 31,494,376 | [['M01.060.057'], ['M01.060.116'], ['D27.505.696.277.950.025', 'D27.505.954.427.210.950.025', 'D27.505.954.427.700.872.025'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F03.615.250.700'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Immunohistochemical staining of cutaneous tumours with G-81, a monoclonal antibody to dermcidin. | BACKGROUND: Recently, the novel antimicrobial peptide named dermcidin (DCD) was reported in human eccrine sweat glands.OBJECTIVES: We investigated the expression of DCD in a variety of cutaneous tumours in order to assess the usefulness of the monoclonal antibody (G-81), which recognizes a fragment of DCD.PATIENTS/METH... | ['Antibodies, Monoclonal', 'Humans', 'Immunohistochemistry', 'Peptides', 'Predictive Value of Tests', 'Skin Neoplasms', 'Sweat Gland Neoplasms'] | 15,270,886 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
ZrO(2)/hydroxyapatite coating on titanium by electrolytic deposition. | In this study, hydroxyapatite (HA) was coated on a titanium (Ti) substrate over a ZrO(2) layer by the electrolytic deposition method, this double layer coating was then compared with a single layer coating of HA. The HA layer was used to increase the bioactivity and osteoconductivity of the Ti substrate, and the ZrO(2)... | ['Coated Materials, Biocompatible', 'Corrosion', 'Durapatite', 'Electric Impedance', 'Electroplating', 'Materials Testing', 'Surface Properties', 'Titanium', 'Zirconium'] | 18,853,237 | [['D25.130.420', 'J01.637.051.130.420'], ['G02.165'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['G01.358.500.249.277.350'], ['E05.301.250.348'], ['E05.570'], ['G02.860'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800'... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Procalcitonin in patients with acute myocardial infarction. | Acute myocardial infarction induces an inflammatory reaction. We related conventional inflammatory parameters including C-reactive protein, erythrocyte sedimentation rate, white blood cell count and axillary temperature to plasma concentrations of procalcitonin in patients with acute myocardial infarction. In a prospec... | ['Adult', 'Aged', 'Aged, 80 and over', 'Austria', 'Blood Sedimentation', 'Body Temperature', 'C-Reactive Protein', 'Calcitonin', 'Calcitonin Gene-Related Peptide', 'Female', 'Humans', 'Leukocyte Count', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Prognosis', 'Prospective Studies', 'Protein Precursors', 'Systemic I... | 12,238,310 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.542.088'], ['E01.370.225.625.125', 'E05.200.625.125'], ['E01.370.600.875.374', 'G07.110'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['D06.472.699.150', 'D06.472.931.052', 'D12.644.400.095', 'D12.644.548.150', 'D12.776.631.65... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of teledermatology on the prognosis of patients with cutaneous melanoma. | OBJECTIVE: To evaluate differences in the initial prognosis of patients with cutaneous melanoma managed by teledermatology (TD) vs other non-TD referral systems.DESIGN: Descriptive and longitudinal study of a store-and-forward TD system aimed at the triage of patients with suspicious pigmented lesions.SETTING: In 2003,... | ['Dermatology', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Melanoma', 'Middle Aged', 'Prognosis', 'Skin Neoplasms', 'Telemedicine'] | 22,986,852 | [['H02.403.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['M01.060.116.630'], ['E01.789'], ['C04.588.805', 'C17.800.882'], ['H02.403.840', 'L01.... | ['Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Decomposition of beclomethasone propionate esters in human plasma. | The kinetics of decomposition of beclomethasone dipropionate (BDP), the 17-monopropionate ester (17-BMP), and beclomethasone (BOH) were characterized in whole human plasma (HP), pH 7.1, and in solutions of 1% human serum albumin (HSA), pH 7.4, and 0.067 M phosphate buffer, pH 7.4 (mu = 0.17). A reversed-phase, high-per... | ['Albumins', 'Beclomethasone', 'Chromatography, High Pressure Liquid', 'Esterases', 'Half-Life', 'Humans', 'Hydrogen-Ion Concentration', 'Kinetics', 'Protein Binding', 'Solubility', 'Solutions'] | 9,510,979 | [['D12.776.034'], ['D04.210.500.745.432.769.125', 'D04.210.500.883.154'], ['E05.196.181.400.300'], ['D08.811.277.352'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['G02.111.679', 'G03.808'], ['G02.805'], ['D26.776']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chitosan oligosaccharide decreases very-low-density lipoprotein triglyceride and increases high-density lipoprotein cholesterol in high-fat-diet-fed rats. | It is well known that chitosan has beneficial lipid-regulating effects, but it remains unknown whether chitosan oligosaccharide (COS), the chitosan degradation product, has the same lipid benefits. High-fat-diet-fed Wistar rats were administrated with COS by gastric gavage for three weeks. The effects of COS on lipids,... | ['Animals', 'Anticholesteremic Agents', 'Chitosan', 'Cholesterol, HDL', 'Chromatography, Liquid', 'Dietary Fats', 'Lipoproteins, VLDL', 'Male', 'Rats', 'Rats, Wistar', 'Triglycerides'] | 21,856,756 | [['B01.050'], ['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['D05.750.078.139.500', 'D09.698.211.500'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['E05.196.181.400'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D10.532.599', 'D12.776.521.622'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Comparison of microtitre plates with flat-bottomed and round-bottomed wells for mixed lymphocyte culture (MLC). | To compare microtitre plates with flat-bottomed and round-bottomed wells and to standardize a method for mixed lymphocyte culture (MLC), the effects of cell number, culture time, 3H-thymidine concentration and labelling time were studied. On both plates, allogeneic cells induced increased RNA synthesis beginning at abo... | ['DNA', 'Dose-Response Relationship, Radiation', 'Humans', 'Isotope Labeling', 'Leukocyte Count', 'Lymphocyte Culture Test, Mixed', 'Lymphocytes', 'Monocytes', 'RNA', 'Radiation Dosage', 'Scintillation Counting'] | 140,586 | [['D13.444.308'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.522'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.107.595', 'G04... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Caring for chronic kidney disease patients: focus on mineral and bone disorders. | This case study focuses on a patient with chronic kidney disease (CKD) with mineral and bone disorders (MBD) and the relationship and management strategies used in treating CKD-MBD. The various risks and issues pertaining to the CKD stage 5 patient population are addressed, including CKD-MBD and renal osteodystrophy. P... | ['Calcium', 'Chelating Agents', 'Chronic Kidney Disease-Mineral and Bone Disorder', 'Cinacalcet', 'Diet Therapy', 'Humans', 'Hyperparathyroidism, Secondary', 'Hyperphosphatemia', 'Kidney Failure, Chronic', 'Metabolic Diseases', 'Middle Aged', 'Naphthalenes', 'Parathyroid Hormone', 'Pharmaceutical Services', 'Phosphorus... | 19,275,456 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.914.500', 'D27.720.832.500'], ['C05.116.198.816.750', 'C12.777.419.080', 'C13.351.968.419.795', 'C18.452.104.816.750', 'C18.452.174.845.750', 'C18.654.521.500.133.770.734.750', 'C19.642.355.480.500'], ['D02.455.426.559.847.638.183', 'D04.615.638.183'... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthetic analogues of SB-219383. Novel C-glycosyl peptides as inhibitors of tyrosyl tRNA synthetase. | Novel inhibitors of bacterial tyrosyl tRNA synthetase have been synthesised in which the cyclic hydroxylamine moiety of SB-219383 is replaced by C-pyranosyl derivatives. Potent and selective inhibition of bacterial tyrosyl tRNA synthetase was obtained. | ['Bacterial Proteins', 'Bridged Bicyclo Compounds, Heterocyclic', 'Enzyme Inhibitors', 'Furans', 'Models, Molecular', 'Molecular Structure', 'Pyrans', 'Staphylococcus aureus', 'Tyrosine-tRNA Ligase'] | 11,266,175 | [['D12.776.097'], ['D03.605.084'], ['D27.505.519.389'], ['D03.383.312'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['D03.383.663'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.100.750.750.100', 'B03.510.400.790.750.100'], ['D08.811.464.263.200.900']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Functional analysis of microRNAs during the retinoic acid-induced neuronal differentiation of human NT2 cells. | MicroRNAs (miRNAs) are phylogenetically widespread small RNAs in animals and plants. These small RNAs can regulate a gene expression at a translational level and play roles during the development of C. elegans, D. melanogaster and plants. Although more than two hundred miRNAs have been found in mammals, the target mRNA... | ['Cell Differentiation', 'Cell Line', 'Humans', 'MicroRNAs', 'Neurons', 'Tretinoin'] | 14,510,471 | [['G04.152'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['A08.675', 'A11.671'], ['D02.455.326.271.665.202.495.818.500', 'D02.455.426.392.368.367.379.249.700.860.500', 'D02.455.849.131.495.818.800', 'D02.455.849.291.925.500', ... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Propofol-nitrous oxide versus sevoflurane-nitrous oxide for strabismus surgery in children. | Vomiting is a common problem following strabismus surgery. We compared the effects of propofol-N2O and sevoflurane-N2O on the incidence of oculocardiac reflex and postoperative nausea and vomiting. Forty unpremedicated children, aged 3-15 years were randomly assigned to two groups of 20 patients. In group 1, anaesthesi... | ['Adolescent', 'Anesthesia, Inhalation', 'Anesthetics, Inhalation', 'Anesthetics, Intravenous', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Methyl Ethers', 'Nitrous Oxide', 'Postoperative Nausea and Vomiting', 'Propofol', 'Reflex, Oculocardiac', 'Sevoflurane', 'Strabismus'] | 10,597,552 | [['M01.060.057'], ['E03.155.197.197'], ['D27.505.696.277.100.035.060', 'D27.505.954.427.210.100.035.060'], ['D27.505.696.277.100.035.075', 'D27.505.954.427.210.100.035.075'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.355.601'], ['D01.362.635.625', 'D01.625.550.550', 'D... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Biologically-generated primer for PCR: PCR primer of unknown sequence. | We describe a method for producing specific PCR primers directly from PCR product, bypassing the usual need to know the primer sequence. Lack of abundance of primers derived from a PCR product is compensated for by the incorporation of an arbitrary 5'TAG sequence which acts as a surrogate template target for the bulk a... | ['Base Sequence', 'DNA', 'DNA Primers', 'Humans', 'Polymerase Chain Reaction', 'Sensitivity and Specificity'] | 9,628,934 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.620.500'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Binding Isotherms and Time Courses Readily from Magnetic Resonance. | Evidence is presented that binding isotherms, simple or biphasic, can be extracted directly from noninterpreted, complex 2D NMR spectra using principal component analysis (PCA) to reveal the largest trend(s) across the series. This approach renders peak picking unnecessary for tracking population changes. In 1:1 bindin... | ['Algorithms', 'Animals', 'Brain', 'Carrier Proteins', 'Glycochenodeoxycholic Acid', 'Magnetic Resonance Imaging', 'Membrane Glycoproteins', 'Nuclear Magnetic Resonance, Biomolecular', 'Principal Component Analysis', 'Protein Binding', 'Proteins'] | 27,458,657 | [['G17.035', 'L01.224.050'], ['B01.050'], ['A08.186.211'], ['D12.776.157'], ['D04.210.500.105.225.272.150.350', 'D04.210.500.105.225.272.411.360', 'D04.210.500.105.225.400.380.360', 'D04.210.500.221.430.342.300.400', 'D04.210.500.221.430.342.400.450', 'D04.210.500.221.430.484.430.420', 'D12.125.481.700.249.420.400'], [... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Public attitudes in Edmonton toward assisted reproductive technology. | OBJECTIVE: To determine public attitudes toward the use and possible limitations of assisted reproductive technology (ART).DESIGN: Mail survey based on telephone numbers selected at random by computer.SETTING: Edmonton.PARTICIPANTS: A total of 602 Edmonton residents aged 16 years or more (57% of eligible subjects) reac... | ['Adolescent', 'Adult', 'Alberta', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', 'Public Opinion', 'Reproductive Techniques', 'Surveys and Questionnaires'] | 8,324,713 | [['M01.060.057'], ['M01.060.116'], ['Z01.107.567.176.064'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.880.630.548'], ['E02.875', 'E05.820'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Combined endoscopic and open approach to the removal of expandable metallic tracheal stents. | OBJECTIVES: To review complications of indwelling tracheal stents and to describe a technique of stent removal using a combined open and endoscopic approach.DESIGN: Descriptive case series.SETTING: Medical University of South Carolina.PATIENTS: Six patients were identified who had undergone combined open and endoscopic... | ['Adolescent', 'Adult', 'Aged', 'Bronchoscopy', 'Device Removal', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Stents', 'Trachea', 'Tracheal Stenosis'] | 17,224,520 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['E04.199'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.750'], ['A04.889'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Protein synthesis and the recovery of both survival and cytoplasmic "petite" mutation in ultraviolet-treated yeast cells. II. Mitochondrial protein synthesis. | The contribution of mitochondrial proteins in the repair of UV-induced lethal and cytoplasmic genetic damages was studied in dark liquid held exponential and stationary phase yeast cells. This was performed by using the specific inhibitors, erythromycin (ER) anc chloramphenicol (CAP). It was shown that mitochondrial pr... | ['Cell Nucleus', 'Cell Survival', 'Chloramphenicol', 'Cytoplasm', 'DNA Repair', 'Darkness', 'Erythromycin', 'Mitochondria', 'Mutation', 'Protein Biosynthesis', 'Radiation Genetics', 'Saccharomyces cerevisiae', 'Ultraviolet Rays'] | 1,095,920 | [['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G04.346'], ['D02.033.455.706.300', 'D02.455.426.559.389.565.175', 'D02.640.529.175'], ['A11.284.430.214'], ['G02.111.222', 'G05.219'], ['G01.590.540.233'], ['D02.540.576.500.992'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G05.365.590'], ['G02.111.660.8... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[The punishment of blinding and the life of the blind]. | The article deals with a group of people who were deprived of their eyesight by private acts of force or by executions of lawful sentences. In early medieval texts blinding is frequently mentioned in connection with popes, kings, princes or bishops. However, since the High Middle Ages these dignitaries were increasingl... | ['Blindness', 'Civil Disorders', 'Criminal Law', 'Eye Injuries', 'Germany', 'History, Medieval', 'Humans', 'Punishment', 'Social Isolation', 'Visually Impaired Persons'] | 20,506,724 | [['C10.597.751.941.162', 'C11.966.075', 'C23.888.592.763.941.162'], ['I01.880.735.140'], ['I01.198.290', 'I01.880.604.583.100'], ['C10.900.300.284.250', 'C11.297', 'C26.915.300.425.250'], ['Z01.542.315'], ['K01.400.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.770.571', 'I01.880.630.716'], ['F01... | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Humanities [K]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Kiwifruit remnants from digestion in vitro have functional attributes of potential importance to health. | The physicochemical properties of plant cell walls in the gut are important in modulating processes that influence health. We investigated the physicochemical properties of kiwifruit cell walls digested under gastric and gastroileal conditions in vitro. Soluble and insoluble undigested polymer fractions were measured, ... | ['Actinidia', 'Dietary Fiber', 'Digestion', 'Fruit', 'Health', 'Humans', 'Models, Biological', 'Viscosity'] | 22,980,789 | [['B01.650.940.800.575.912.250.341.500.500'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['G07.203.650.250', 'G10.261.190'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['N01.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['G02.930']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Solitary splenic metastasis of bladder carcinoma. Report of a clinical case]. | Several authors assumed that spleen was resistant to neoplastic dissemination because of spleen metastasis are rare in relation to the incidence of metastasis in other parenchymatous organs. We report a clinical case of a symptomatic solitary spleen metastasis in cystic-looking bladder cancer; afterwards we'll examine ... | ['Aged', 'Carcinoma, Transitional Cell', 'Humans', 'Male', 'Splenic Neoplasms', 'Urinary Bladder Neoplasms'] | 9,082,218 | [['M01.060.116.100'], ['C04.557.470.200.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.842', 'C15.604.744.680'], ['C04.588.945.947.960', 'C12.758.820.968', 'C12.777.829.813', 'C13.351.937.820.945', 'C13.351.968.829.707']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effectiveness of antipsychotics in first-episode schizophrenia and schizophreniform disorder on response and remission: an open randomized clinical trial (EUFEST). | BACKGROUND: Predefined response and remission criteria may hold more clinical relevance than mean scores on rating scales. We compared the effectiveness of low doses of haloperidol and regular doses of second generation antipsychotics (SGAs) on >or=50% response and remission.METHODS: In an open randomized clinical tria... | ['Adolescent', 'Adult', 'Antipsychotic Agents', 'Cross-Cultural Comparison', 'Dose-Response Relationship, Drug', 'Europe', 'Female', 'Humans', 'International Cooperation', 'Israel', 'Male', 'Outcome Assessment, Health Care', 'Predictive Value of Tests', 'Proportional Hazards Models', 'Psychiatric Status Rating Scales',... | 19,819,114 | [['M01.060.057'], ['M01.060.116'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['G07.690.773.875', 'G07.690.936.500'], ['Z01.542'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615.500'], ['Z01.252.245.500.375'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry a... | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
The contingent negative variation in a Go/No Go avoidance task: relationships with personality and subjective state. | Howard et al. (1982) reported an association in mentally abnormal offenders between psychometric impulsiveness and the degree of differentiation in the contingent negative variation (CNV) recorded at the vertex between Go and No Go conditions in a Go/No Go signalled avoidance task. The present study aimed to investigat... | ['Adolescent', 'Adult', 'Arousal', 'Avoidance Learning', 'Cerebral Cortex', 'Contingent Negative Variation', 'Electrophysiology', 'Female', 'Humans', 'Male', 'Personality', 'Personality Tests', 'Psychometrics'] | 2,925,463 | [['M01.060.057'], ['M01.060.116'], ['F02.830.104', 'G11.561.035'], ['F02.463.425.097', 'F02.463.785.373.173'], ['A08.186.211.200.885.287.500'], ['G07.265.216.500.250', 'G11.561.200.500.250'], ['H01.158.344.528', 'H01.158.782.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752'], ['F04.711.647'], ['F04.711... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Pial arteriolar constriction following cortical spreading depression is mediated by prostanoids. | The mechanism of pial arteriolar constriction during post-cortical spreading depression (CSD) was examined in anesthetized adult rabbits. Using a closed cranial window and intravital microscopy, the diameter of a pial arteriole was determined. A single CSD was induced by KCl micro-injection and its propagation was moni... | ['Animals', 'Arterioles', 'Cortical Spreading Depression', 'Cyclooxygenase Inhibitors', 'Indomethacin', 'Muscle Tonus', 'Perfusion', 'Pia Mater', 'Prostaglandins', 'Rabbits', 'Vasoconstriction'] | 1,611,512 | [['B01.050'], ['A07.015.114.060', 'A07.015.461.080'], ['G11.561.200.500.300'], ['D27.505.519.389.310', 'D27.505.696.663.850.014.040.500.500', 'D27.505.954.158.030.500', 'D27.505.954.329.030.500'], ['D03.633.100.473.420'], ['G11.427.565'], ['E05.680'], ['A08.186.566.731'], ['D10.251.355.255.550', 'D23.469.050.175.725'],... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enhancement of DNA vaccine potency by electroporation in vivo. | The potential of electric current-mediated delivery technology to enhance DNA delivery and DNA vaccine potency was evaluated. Higher levels of reporter gene expression were observed in muscle cells of mice inoculated with luciferase or beta-galactosidase DNA followed by the application of electrical current, compared w... | ['Animals', 'Electroporation', 'Female', 'Gene Products, gag', 'Mice', 'Vaccines, DNA'] | 11,000,470 | [['B01.050'], ['E05.200.500.454', 'E05.242.448', 'E05.301.500'], ['D12.776.775.330', 'D12.776.964.775.350', 'D12.776.964.970.600.850.350'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.828.868.910', 'D20.215.894.865.910', 'D23.050.865.910']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Has the quality of reporting of randomized controlled trials in thoracic surgery improved? | OBJECTIVES: To evaluate the quality of reporting of randomized controlled trials (RCTs) in the thoracic surgery literature according to Consolidated Standard for Reporting of Trials (CONSORT) and to determine predictors of quality.METHODS: All RCTs published in four principal journals between 1998 and 2013 were identif... | ['Biomedical Research', 'Humans', 'Linear Models', 'Publications', 'Randomized Controlled Trials as Topic', 'Retrospective Studies', 'Thoracic Surgical Procedures'] | 26,503,723 | [['H01.770.644.145'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['L01.178.682'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.... | ['Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Prevalence of anemia among under-5 children in the Ghanaian population: estimates from the Ghana demographic and health survey. | BACKGROUND: Anemia in children continues to be a major public health challenge in most developing countries, particularly in Africa. Anemia in the early stages of life leads to severe negative consequences on the cognitive as well as the growth and development of children, which may persist even after treatment. We exa... | ['Africa', 'Anemia', 'Child, Preschool', 'Demography', 'Developing Countries', 'Female', 'Ghana', 'Health Services Needs and Demand', 'Health Surveys', 'Humans', 'Male', 'Prevalence', 'Public Health'] | 24,946,725 | [['Z01.058'], ['C15.378.071'], ['M01.060.406.448'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['I01.615.500.300'], ['Z01.058.290.190.320'], ['N03.349.380.420', 'N05.300.450'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.9... | ['Geographicals [Z]', 'Diseases [C]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Is childhood-onset type I diabetes a wealth-related disease? An ecological analysis of European incidence rates. | AIMS/HYPOTHESIS: To describe the epidemiology of childhood-onset Type I (insulin-dependent) diabetes mellitus in Europe, the EURODIAB collaborative group established prospective, geographically-defined registers of children diagnosed under 15 years of age. A total of 16,362 cases were registered by 44 centres during th... | ['Adolescent', 'Child', 'Diabetes Mellitus, Type 1', 'Ecology', 'Europe', 'Geography', 'Humans', 'Incidence', 'Registries', 'Socioeconomic Factors'] | 11,724,424 | [['M01.060.057'], ['M01.060.406'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['H01.158.273.248', 'H01.277.249'], ['Z01.542'], ['H01.277.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], [... | ['Named Groups [M]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
[Post-dural puncture headache: treatment and prevention]. | Post-dural puncture headache (PDPH) is a common iatrogenic and incapacitating complication. Dural puncture can be intentional (spinal block, myelography,...) or accidental (epidural block). Risk factors are well described and the obstetric patient is at high risk for PDPH. The treatment of PDPH is not standardised. Man... | ['Acetaminophen', 'Analgesics, Non-Narcotic', 'Anesthesia, Epidural', 'Anesthesia, Obstetrical', 'Anesthesia, Spinal', 'Anti-Inflammatory Agents, Non-Steroidal', 'Blood Patch, Epidural', 'Drug Therapy, Combination', 'Female', 'Humans', 'Post-Dural Puncture Headache', 'Pregnancy', 'Risk Factors', 'Spinal Puncture', 'Tre... | 22,216,730 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['D27.505.696.663.850.014.040', 'D27.505.954.427.040.100'], ['E03.155.086.131'], ['E03.155.364'], ['E03.155.086.331'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['E02.095.125', 'E02.319.267.530.580.300.145'], ['E02.319.310'], ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
One case of rotational subluxation of the carpal scaphoid. | The authors describe one case of perilunate dislocation. After reduction of the dislocation, there was a residual rotational subluxation of the scaphoid due to dorsal tearing of the scapho-triquetral and radio-scaphoid ligaments. The subluxation results in post-traumatic dorsal instability of the carpus. The authors re... | ['Bone Wires', 'Carpal Bones', 'Humans', 'Joint Dislocations', 'Ligaments, Articular', 'Male', 'Radiography'] | 1,783,559 | [['E07.695.370.468', 'E07.858.442.660.460.468', 'E07.858.690.725.460.468'], ['A02.835.232.087.319.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['A02.513.514', 'A02.835.583.512', 'A10.165.669.514'], ['E01.370.350.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Haptoglobin deficiency facilitates the development of autoimmune inflammation. | Haptoglobin (HP) is an acute phase protein synthesized by liver cells in response to IL-6. HP has been demonstrated to modulate the immune response and to have anti-inflammatory activities. To analyze HP's effect on autoimmune inflammation, we here studied the course of EAE induced by immunization of Hp knockout (Hp(-/... | ['Animals', 'Autoimmune Diseases', 'Brain', 'Encephalomyelitis, Autoimmune, Experimental', 'Enzyme-Linked Immunosorbent Assay', 'Glycoproteins', 'Haptoglobins', 'Immunization', 'Immunoglobulin G', 'Inflammation', 'Interferon-gamma', 'Interleukin-10', 'Interleukin-17', 'Lymph Nodes', 'Mice', 'Mice, Inbred BALB C', 'Mice... | 19,795,414 | [['B01.050'], ['C20.111'], ['A08.186.211'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.314.350.250', 'C20.111.258.625.300', 'E05.598.500.500.500'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D09.400.430', 'D12.776.395'], ['D12.776.124.... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A novel method for the preparation of 4-arylimidazolones. | A series of 4-arylimidazolones have been accessed via late-stage, palladium-mediated arylation of acetone- and cyclohexanone-derived 4-chloroimidazolones. The 4-chloroimidazolones were prepared via a novel rearrangement of the corresponding imidazolone N-oxides. This communication serves as an expansion of chemistry or... | ['Catalysis', 'Cyclic N-Oxides', 'Cyclohexanones', 'Imidazoles', 'Molecular Structure', 'Palladium', 'Receptors, Glucagon'] | 23,713,942 | [['G02.130'], ['D03.661.243'], ['D02.455.426.392.368.367.340', 'D02.522.400'], ['D03.383.129.308'], ['G02.111.570', 'G02.466'], ['D01.268.556.680', 'D01.268.956.718', 'D01.552.544.680'], ['D12.776.543.750.695.330', 'D12.776.543.750.750.580.350']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Opposite modulation of brain functional networks implicated at low vs. high demand of attention and working memory. | BACKGROUND: Functional magnetic resonance imaging (fMRI) studies indicate that the brain organizes its activity into multiple functional networks (FNs) during either resting condition or task-performance. However, the functions of these FNs are not fully understood yet.METHODOLOGY/PRINCIPAL FINDINGS: To investigate the... | ['Adult', 'Attention', 'Brain', 'Brain Mapping', 'Female', 'Frontal Lobe', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Memory', 'Nerve Net', 'Parietal Lobe', 'Photic Stimulation', 'Psychomotor Performance', 'Radiography', 'Time Factors', 'Young Adult'] | 24,498,021 | [['M01.060.116'], ['F02.830.104.214'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['F02.463.425.540'], ['A08.511'], ['A08.186.211.200.885.287.500.670'], ['E05.7... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Molecular-recognition-assisted pKa shifts and metal-ion-induced fluorescence regeneration in p-sulfonatocalix[6]arene-encapsulated acridine. | The host-guest interactions of cationic (AcH(+) ) and neutral (Ac) forms of the dye acridine with the macrocyclic host p-sulfonatocalix[6]arene (SCX6) were investigated by using ground-state absorption, steady-state and time-resolved fluorescence, and NMR measurements. The cationic form undergoes significant complexati... | ['Acridines', 'Calixarenes', 'Gadolinium', 'Hydrogen-Ion Concentration', 'Ions', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Phenols', 'Spectrometry, Fluorescence', 'Sulfones'] | 25,404,418 | [['D03.633.300.046'], ['D04.345.025'], ['D01.268.558.362.484', 'D01.552.550.399.484'], ['G02.300'], ['D01.248.497'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519'], ['D02.455.426.559.389.657'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['D02.886.590']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evidence of Rab3A expression, regulation of vesicle trafficking, and cellular secretion in response to heregulin in mammary epithelial cells. | Heregulin beta1 (HRG), a combinatorial ligand for human growth factor receptors 3 and 4, is a regulatory polypeptide that promotes the differentiation of mammary epithelial cells into secretory lobuloalveoli. Emerging evidence suggests that the processes of secretory pathways, such as biogenesis and trafficking of vesi... | ['Animals', 'Breast', 'Breast Neoplasms', 'Cell Compartmentation', 'Cell Membrane', 'Dexamethasone', 'Epithelial Cells', 'Exocytosis', 'Female', 'Gene Expression Regulation', 'Humans', 'Insulin', 'Intracellular Membranes', 'Lactation', 'Mammary Glands, Animal', 'Mice', 'Neuregulin-1', 'Prolactin', 'Protein Transport', ... | 11,074,007 | [['B01.050'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['G04.128'], ['A11.284.149'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['A11.436'], ['G04.468'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['A11.284.149.450',... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thermo-and pH-sensitive hydrogel membranes composed of poly(N-isopropylacrylamide)-hyaluronan for biomedical applications: Influence of hyaluronan incorporation on the membrane properties. | Interpenetrating hydrogel membranes consisting of pH-sensitive hyaluronan (HA) and thermo-sensitive poly(N-isopropylacrylamide) (PNIPAAM) were synthesized using redox polymerization, followed by N,N-methylenebisacrylamide (BIS) and epichlorohydrin (EPI) were added as chemical crosslinkers. The interaction between membr... | ['Acrylamides', 'Acrylic Resins', 'Ampicillin', 'Anti-Bacterial Agents', 'Candida albicans', 'Cross-Linking Reagents', 'Drug Carriers', 'Drug Liberation', 'Epichlorohydrin', 'Hyaluronic Acid', 'Hydrogels', 'Hydrogen-Ion Concentration', 'Kinetics', 'Membranes, Artificial', 'Microbial Sensitivity Tests', 'Oxidation-Reduc... | 28,780,413 | [['D02.065.122', 'D02.241.081.069.094'], ['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['D27.505.954.122.085'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['D27.720... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Partial structures of ketoconazole as modulators of the large conductance calcium-activated potassium channel (BK(Ca)). | A series of partial structures of ketoconazole has been synthesized and tested for activity on the large conductance calcium-activated potassium channel (BK) in bovine smooth muscle cells. This has provided openers and blockers of the channel. The results suggest that the phenyl and phenoxy moieties are important for i... | ['Animals', 'Cattle', 'Drug Evaluation, Preclinical', 'Ketoconazole', 'Large-Conductance Calcium-Activated Potassium Channels', 'Membrane Transport Modulators', 'Molecular Structure', 'Muscle, Smooth, Vascular', 'Structure-Activity Relationship'] | 16,359,866 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.290.750', 'E05.337.550'], ['D03.383.606.560'], ['D12.776.157.530.400.600.150.500', 'D12.776.543.550.450.750.150.500', 'D12.776.543.585.400.750.150.500'], ['D27.505.519.562'], ['G02.111.570', 'G02.466'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dissociation of sympathoexcitatory and vasodilator actions of modestly elevated plasma insulin levels. | OBJECTIVE: To determine sympathetic and vascular responses to modest increases in plasma insulin level.BACKGROUND: Most studies of sympathetic and vascular actions of insulin have evaluated high plasma insulin levels ( > 50 microU/ml). Those levels increase sympathetic nerve activity but also cause vasodilation. Hypert... | ['Adult', 'Blood Glucose', 'Body Mass Index', 'Female', 'Forearm', 'Glucose Clamp Technique', 'Hemodynamics', 'Humans', 'Insulin', 'Male', 'Muscle, Skeletal', 'Sympathetic Fibers, Postganglionic'] | 8,586,819 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['A01.378.800.585'], ['E01.370.225.124.100.350', 'E05.196.500', 'E05.200.124.100.350'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
On associations between computers and restaurants: rapid learning of new associations on a conceptual implicit memory test. | A novel event-based conceptual implicit memory test was designed to tap the development of new associations between objects and ad hoc categories. At study, participants were presented with a plausible story that linked an incongruous object (computer) with an ad hoc category (restaurant). At test, participants judged ... | ['Adult', 'Attention', 'Computers', 'Concept Formation', 'Cues', 'Female', 'Humans', 'Male', 'Mental Recall', 'Paired-Associate Learning', 'Reaction Time', 'Restaurants'] | 11,105,516 | [['M01.060.116'], ['F02.830.104.214'], ['L01.224.230.260'], ['F02.463.785.233'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['F02.463.425.952.500'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['J01.576.423.500.700', 'J03.813']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
Completion of Schistosoma mansoni life cycle in thyroidectomized rats and effects of thyroid hormone replacement therapy. | The survival and maturation of Schistosoma mansoni worms was analyzed in normal, thyroidectomized (Thyrox), and hormone-restored Thyrox rats. Restoration therapy was conducted with both T3 and T4; weight gain of treated rats was monitored to assess hormone-replacement efficacy. Worm yields, lengths, and sex-ratios were... | ['Animals', 'Body Weight', 'Female', 'Liver', 'Male', 'Ovum', 'Rats', 'Rats, Inbred Strains', 'Schistosoma mansoni', 'Schistosomiasis', 'Thyroidectomy', 'Thyroxine', 'Triiodothyronine'] | 4,032,149 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A03.620'], ['A05.360.490.690', 'A11.497.497', 'A16.690'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['B01.05... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pain-behavior contracts: effective management of the adolescent in sickle-cell crisis. | Pain-behavior contracts can be utilized as an alternative method of managing the discomfort experienced by adolescents in sickle-cell crisis. The psychological impact of sickle-cell disease, the developmental need of adolescents to control situations in which they find themselves, and principles of pain control all pro... | ['Adolescent', 'Anemia, Sickle Cell', 'Humans', 'Male', 'Pain', 'Pain Management', 'Patient Care Planning', 'Patient Participation'] | 2,614,647 | [['M01.060.057'], ['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E02.745', 'N04.590.607.500'], ['N04.590.233.624'], ['F01.100.150.750.500.620', 'F01.145.488.887.500.620', ... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular characterization of Aspergilli isolated from outdoor air. | Ubiquitous airborne conidia of the genus Aspergillus are responsible for a diverse group of human disorders from allergy to life treating invasive aspergillosis and mycotoxicoses. The aim of this study was to determine the population structure of Aspergillus isolated from outdoor air in Tehran by comparing the nucleoti... | ['Air Microbiology', 'Aspergillus', 'DNA, Fungal', 'DNA, Ribosomal Spacer', 'Iran', 'Molecular Typing', 'Mycological Typing Techniques', 'Phylogeny', 'Polymerase Chain Reaction', 'Polymorphism, Restriction Fragment Length', 'Sequence Analysis, DNA'] | 30,292,392 | [['H01.158.273.540.274.110', 'N06.850.425.110'], ['B01.300.381.081'], ['D13.444.308.300'], ['D13.444.308.324.230', 'D13.444.308.475.230'], ['Z01.252.245.500.350'], ['E01.370.225.875.150.125.457', 'E05.200.875.150.125.457', 'E05.393.542'], ['E01.370.225.875.610', 'E05.200.875.610'], ['G05.697', 'G16.075.605', 'L01.100.6... | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Acute bilateral central serous chorioretinopathy following intra-articular injection of corticosteroid. | There is increasing evidence in the literature implicating the use of exogenous steroids through various routes as a risk factor for the development of idiopathic central serous chorioretinopathy (ICSC). We report a case of acute bilateral ICSC following intra-articular injection of corticosteroids. | ['Acute Disease', 'Adult', 'Blood', 'Choroid Diseases', 'Female', 'Fluorescein Angiography', 'Glucocorticoids', 'Humans', 'Injections, Intra-Articular', 'Retinal Diseases', 'Tenosynovitis', 'Triamcinolone Acetonide', 'Wrist Joint'] | 15,976,473 | [['C23.550.291.125'], ['M01.060.116'], ['A12.207.152', 'A15.145'], ['C11.941.160'], ['E01.370.370.050.350', 'E01.370.380.250'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.380'], ['C11.768'], ['C05.651.869.870'], ['D04.210.500.745.432.915.715', 'D04... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Outpatient therapy of serious pediatric infections with ceftriaxone. | Convalescent outpatient parenteral antibiotic therapy with ceftriaxone was evaluated in an uncontrolled study of 101 children with documented serious bacterial infections, including meningitis. Criteria for outpatient therapy were established to assure that risks of complications from the illness were minimal at the ti... | ['Adolescent', 'Ambulatory Care', 'Bacterial Infections', 'Bacterial Toxins', 'Blood Bactericidal Activity', 'Ceftriaxone', 'Child', 'Child, Preschool', 'Clostridium Infections', 'Diarrhea', 'Feces', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Meningitis', 'Prognosis', 'Prospective Studies'] | 3,357,713 | [['M01.060.057'], ['E02.760.106', 'N02.421.585.106'], ['C01.150.252'], ['D23.946.123'], ['G09.188.100', 'G12.450.564.204'], ['D02.065.589.099.249.190.190.155', 'D02.886.665.074.190.190.155', 'D03.633.100.300.249.190.190.155'], ['M01.060.406'], ['M01.060.406.448'], ['C01.150.252.410.222'], ['C23.888.821.214'], ['A12.459... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acquisition of hemozoin by monocytes down-regulates interleukin-12 p40 (IL-12p40) transcripts and circulating IL-12p70 through an IL-10-dependent mechanism: in vivo and in vitro findings in severe malarial anemia. | Severe malarial anemia (SMA) is a primary cause of morbidity and mortality in immune-na?ve infants and young children residing in areas of holoendemic Plasmodium falciparum transmission. Although the immunopathogenesis of SMA is largely undefined, we have previously shown that systemic interleukin-12 (IL-12) production... | ['Anemia', 'Animals', 'Antibodies', 'Cells, Cultured', 'Child, Preschool', 'Down-Regulation', 'Female', 'Hemeproteins', 'Humans', 'Infant', 'Infant, Newborn', 'Interleukin-10', 'Interleukin-12', 'Interleukin-12 Subunit p40', 'Lipopolysaccharide Receptors', 'Malaria, Falciparum', 'Male', 'Monocytes', 'Phagocytosis', 'Pl... | 16,926,419 | [['C15.378.071'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['A11.251'], ['M01.060.406.448'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D12.776.422'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['D12.644.276.374... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The bactericidal power of the blood and plasma of patients with burns. | Patients with burns are unusually susceptible to bacterial infections, but so far there is no satisfactory explanation for this lack of resistance. Since resistance to infection involves many different mechanisms, examination of individual components of the immune system may not sufficiently explain the underlying reas... | ['Blood Bactericidal Activity', 'Burns', 'Female', 'Humans', 'Klebsiella pneumoniae', 'Male', 'Plasma', 'Staphylococcus aureus'] | 2,050,718 | [['G09.188.100', 'G12.450.564.204'], ['C26.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.440.450.425.425.600', 'B03.660.250.150.400.590'], ['A12.207.152.693', 'A12.207.270.695', 'A15.145.693'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.100.750.750.100', 'B03.510.400.790.750.100... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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