Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Infant physiological regulation and maternal risks as predictors of dyadic interaction trajectories in families with a preterm infant. | This longitudinal study examined predictors of rates of growth in dyadic interaction quality in children born preterm who did not experience significant neurological findings during neonatal intensive care unit (NICU) hospitalization. Multiple methods were used to collect data from 120 preterm infants (48% girls, 52% b... | ['Adult', 'Affect', 'Age Factors', 'Attention', 'Child Development', 'Family', 'Female', 'Heart Rate', 'Humans', 'Infant', 'Infant Behavior', 'Infant, Newborn', 'Infant, Premature', 'Intensive Care Units, Neonatal', 'Longitudinal Studies', 'Male', 'Mother-Child Relations', 'Play and Playthings', 'Pregnancy', 'Risk Fact... | 21,244,152 | [['M01.060.116'], ['F01.470.047'], ['N05.715.350.075', 'N06.850.490.250'], ['F02.830.104.214'], ['F01.525.200', 'G07.345.374.750'], ['F01.829.263', 'I01.880.853.150'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.145.179.500'], ['M01.060.703.520'], ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Unusual association of squamous and follicular carcinoma of the thyroid]. | The Authors report a case of thyroid squamous cell carcinoma associated to a counterlateral lobe follicular carcinoma, they had the opportunity to observe. The histogenetic hypotheses and problems of differential diagnosis are discussed. | ['Adenocarcinoma', 'Carcinoma, Squamous Cell', 'Diagnosis, Differential', 'Female', 'Humans', 'Middle Aged', 'Neoplasms, Multiple Primary', 'Thyroid Neoplasms'] | 6,680,671 | [['C04.557.470.200.025'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.651'], ['C04.588.322.894', 'C04.588.443.915', 'C19.344.894', 'C19.874.788']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Differential regulation of mouse B cell development by transforming growth factor beta1. | Transforming growth factor beta (TGFbeta) can inhibit the in vitro proliferation, survival and differentiation of B cell progenitors, mature B lymphocytes and plasma cells. Here we demonstrate unexpected, age-dependent reductions in the bone marrow (BM) B cell progenitors and immature B cells in TGFbeta1-/- mice. To ev... | ['Animals', 'B-Lymphocytes', 'Cell Differentiation', 'Cell Division', 'Female', 'Flow Cytometry', 'Hematopoietic Stem Cells', 'In Vitro Techniques', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Transforming Growth Factor beta', 'Transforming Growth Factor beta1'] | 12,739,785 | [['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Genetic techniques--chances--risks--limits (from the viewpoint of the legislator--ethical questions--status of medical research]. | Gene technology is still a very young area of research. Advantages or disadvantages of this development cannot be tangibly predicted. Irrational desires and fears have surfaced resulting from the fact that we are now in a position of cultivate certain biological characteristics hitherto impossible to reproduce. Individ... | ['Ethics, Medical', 'Genetic Techniques', 'Genetic Testing', 'Germany', 'Humans', 'Research', 'Risk Factors'] | 1,811,494 | [['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['E05.393'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.70... | ['Humanities [K]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Secretion of prolactin-synergizing activity (synlactin) by the liver of ectothermic vertebrates in vitro. | Recent work in our laboratory indicated that the liver of rats and pigeons secretes a prolactin synergist (synlactin) in vitro. We have investigated the secretion of this activity by the liver of nine species of ectothermic vertebrates. Liver from three teleosts (goby, salmon, and tilapia), four amphibians (Ambystoma, ... | ['Amphibians', 'Animals', 'Columbidae', 'Fishes', 'Larva', 'Liver', 'Prolactin', 'Proteins', 'Reptiles'] | 3,711,821 | [['B01.050.150.900.090'], ['B01.050'], ['B01.050.150.900.248.165.150'], ['B01.050.150.900.493'], ['B05.500.500', 'G07.345.500.550.500.500'], ['A03.620'], ['D06.472.699.322.576.773', 'D06.472.699.631.525.525', 'D12.644.548.691.525.525'], ['D12.776'], ['B01.050.150.900.833']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Cutaneomucous hyalinosis in monozygotic twins]. | Two Urbach-Wiethe disease cases in both univitelline twins sisters, 8 years old, are presented. Consanguinity is demonstrated in their parents and we consider this to be the second study of this type described in Spain and the first one in the world with such genetic features. We emphasize the early process apparition-... | ['Basement Membrane', 'Capillaries', 'Child', 'Consanguinity', 'Diseases in Twins', 'Female', 'Fibroblasts', 'Humans', 'Lipidoses', 'Lipoid Proteinosis of Urbach and Wiethe', 'Pedigree', 'Skin', 'Twins, Monozygotic'] | 4,062,170 | [['A10.272.220', 'A10.615.179'], ['A07.015.461.165'], ['M01.060.406'], ['G05.090.403.180', 'G05.180'], ['C23.550.291.750'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.565.398.641', 'C18.452.584.687', 'C18.452.648.398.641'], ['C08.618.490.500', 'C16.320.850.595'], ['E05.393.673'], ['A17.... | ['Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Climate influence on dengue epidemics in Puerto Rico. | The variability of the insect-borne disease dengue in Puerto Rico was studied in relation to climatic variables in the period 1979-2005. Annual and monthly reported dengue cases were compared with precipitation and temperature data. Results show that the incidence of dengue in Puerto Rico was relatively constant over t... | ['Animals', 'Climate', 'Dengue', 'Disease Outbreaks', 'Greenhouse Effect', 'Humans', 'Insect Vectors', 'Puerto Rico', 'Rain', 'Seasons', 'Time Factors', 'Weather'] | 18,821,372 | [['B01.050'], ['G16.500.275.071', 'N06.230.300.100.250'], ['C01.920.500.270', 'C01.925.081.270', 'C01.925.782.350.250.214', 'C01.925.782.417.214'], ['N06.850.290'], ['G16.500.175.827', 'N06.230.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['Z01.107.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Nicotinamide adenine dinucleotide glycohydrolase activity in guinea pig polymorphonuclear leukocytes. | An enzyme is present in extracts of guinea pig polymorphonuclear leukocytes which can catalyze the hydrolysis of pyridine nucleotides. The enzyme is equally active toward nicotinamide adenine dinucleotide (NAD) or NAD phosphate, has an acid pH optimum, and is inhibited by either nicotinamide or isonicotinic acid hydraz... | ['Albumins', 'Animals', 'Azides', 'Blood Proteins', 'Carbon Isotopes', 'Chemical Phenomena', 'Chemistry', 'Chromatography', 'Cyanides', 'Guinea Pigs', 'Hydrogen-Ion Concentration', 'In Vitro Techniques', 'Kinetics', 'Leukocytes', 'N-Glycosyl Hydrolases', 'NAD', 'NADP', 'Niacinamide', 'Time Factors'] | 4,404,683 | [['D12.776.034'], ['B01.050'], ['D01.625.100', 'D02.159'], ['D12.776.124'], ['D01.268.150.075', 'D01.496.123'], ['G02'], ['H01.181'], ['E05.196.181'], ['D01.248.497.158.291', 'D01.625.400.100'], ['B01.050.150.900.649.313.992.550'], ['G02.300'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['A11.118.637', 'A15.145.229.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Tubular secretion of phosphate in the human kidney (author's transl)]. | There are a few scattered publications on primary tubulopathies, where a net secretion of phosphorus by renal tubules, a mechanism usually not existing in man, is shown. By means of a further case, we are able to demonstrate a 30% increase of phosphate excretion over filtration after a phosphate load. The mechanism of ... | ['Adolescent', 'Biological Transport', 'Glycosuria, Renal', 'Humans', 'Kidney Tubules', 'Male', 'Phosphates'] | 714,486 | [['M01.060.057'], ['G03.143'], ['C12.777.419.815.532', 'C12.777.934.363.450', 'C13.351.968.419.815.532', 'C13.351.968.934.363.450', 'C16.320.831.532', 'C18.452.394.937.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453.736.560'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625.675.650... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Escherichia coli serotype K45 capsular antigen: a glycan containing 3-acetamido-3,6-dideoxygalactopyranose. | The primary structure of the acidic capsular antigen of Escherichia coli O8:K45:H9 was shown by glycose analysis, methylation analysis, and one- and two-dimensional 1H and 13C NMR spectroscopy to be composed of repeating branched tetrasaccharide units having the structure: [formula: see text] The polysaccharide contain... | ['Acetylgalactosamine', 'Acetylglucosamine', 'Antigens, Bacterial', 'Carbohydrate Conformation', 'Carbohydrate Sequence', 'Escherichia coli', 'Fucose', 'Galactose', 'Magnetic Resonance Spectroscopy', 'Molecular Sequence Data', 'Oligosaccharides', 'Polysaccharides, Bacterial'] | 8,252,534 | [['D09.067.342.356.050'], ['D09.067.342.531.050'], ['D23.050.161'], ['G02.111.570.820.235'], ['G02.111.570.160', 'L01.453.245.667.160'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D09.254.488'], ['D09.947.875.359.377'], ['E05.196.867.519'], ['L01.453.245.667'], ['D09.698.629'], ['D09.698.718', 'D23.050.1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Plausibility effects when reading one- and two-character words in Chinese: evidence from eye movements. | Eye movements of Chinese readers were monitored as they read sentences containing a critical character that was either a 1-character word or the initial character of a 2-character word. Due to manipulation of the verb prior to the target word, the 1-character target word (or the first character of the 2-character targe... | ['Eye Movement Measurements', 'Eye Movements', 'Humans', 'Language', 'Pattern Recognition, Visual', 'Probability', 'Reading'] | 22,612,173 | [['E01.370.380.230', 'E01.370.405.245.787'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600'], ['L01.559.423.557']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Meniscal tears sustained awaiting anterior cruciate ligament reconstruction. | We reviewed 68 patients who underwent anterior cruciate ligament (ACL) reconstruction after initial EUA & arthroscopy in the knee unit of a United Kingdom district general hospital. Mean time between injury and ACL reconstruction surgery was 23.3 months with the incidence of meniscal tear at reconstruction being 67.6%.... | ['Adolescent', 'Adult', 'Anterior Cruciate Ligament Injuries', 'Arthroscopy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Reconstructive Surgical Procedures', 'Retrospective Studies', 'Rupture', 'Tibial Meniscus Injuries', 'Treatment Outcome', 'United Kingdom', 'Waiting Lists'] | 12,719,161 | [['M01.060.057'], ['M01.060.116'], ['C26.558.554.213'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.680'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Noncirrhotic liver fibrosis after chronic arsenic poisoning]. | A 67-year-old woman with portal hypertension, splenomegaly without portal vein thrombosis, leucopenia and thrombocytopenia of splenic origin had repeated episodes of life-threatening haemorrhage from esophageal varices. Since childhood she had suffered from psoriasis and had been treated over a period of 15 years with ... | ['Aged', 'Arsenic Poisoning', 'Arsenites', 'Biopsy', 'Carcinoma, Basal Cell', 'Female', 'Humans', 'Liver', 'Liver Cirrhosis', 'Potassium', 'Potassium Compounds', 'Psoriasis', 'Skin', 'Skin Neoplasms', 'Time Factors'] | 2,806,096 | [['M01.060.116.100'], ['C10.720.475.150', 'C25.723.098'], ['D01.075.050', 'D01.248.497.158.055'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.557.470.200.165', 'C04.557.470.565.165'], ['B01.050.150.900.649.313.988.4... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Immunofluorescence Tomography: High-resolution 3-D reconstruction by serial-sectioning of methacrylate embedded tissues and alignment of 2-D immunofluorescence images. | Immunofluorescence tomography is a high-resolution 3-D reconstruction method based on methacrylate embedding and serial-sectioning, where 2-D images of immuno-stained serial-sections are computationally aligned into image stacks, and the 3-D volume rendered. Butyl-Methyl Methacrylate (BMMA) plastic was adopted as it pr... | ['Animals', 'Cornea', 'Fluorescent Antibody Technique', 'Hair Follicle', 'Histological Techniques', 'Imaging, Three-Dimensional', 'Mammary Glands, Animal', 'Methacrylates', 'Mice', 'Mice, Transgenic', 'Microscopy, Electron', 'Microtomy', 'Tissue Embedding', 'Tomography'] | 30,760,855 | [['B01.050'], ['A09.371.060.217'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['A10.272.497.500', 'A17.360.710', 'A17.815.250.500'], ['E01.370.225.750', 'E05.200.750'], ['E01.370.350.400', 'L01.224.308.410'], ['A10.336.482', '... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Reverie-informed research interviewing. | Drawing on Thomas Ogden's notion of 'reverie', the role of self-reflection in research interviewing is explored. Ogden views reverie as a co-created intersubjective phenomenon, a 'third', distinct from both analyst and patient. Two face-to-face research interviews with adolescent depression sufferers are described, sho... | ['Countertransference', 'Humans', 'Interviews as Topic', 'Professional-Patient Relations', 'Psychoanalysis', 'Qualitative Research', 'Research Design', 'Unconscious, Psychology'] | 28,627,105 | [['F04.754.720.864.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['F01.829.401.650', 'N05.300.660'], ['F04.096.544.779'], ['H01.770.644.241.850'], ['E05.581.500', 'H01.770.644.728'], ['F01.752.747.930', 'F02.739.794.942']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[Optimizing cultural conditions of measles vaccine working seed lot with orthogonal experiments]. | OBJECTIVE: To improve the quality of measles vaccine and find out good combination of cultural factors of measles vaccine virus seeds.METHODS: Orthogonal experiments were made to confirm optimized cultural factors. 5 lots of optimized measles vaccine working seed lot were prepared.RESULTS: The titers of the optimized v... | ['Culture Media', 'Humans', 'Measles Vaccine', 'Measles virus', 'Vaccines, Attenuated', 'Virulence', 'Virus Cultivation'] | 12,910,678 | [['D27.720.470.305', 'E07.206'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.215.894.899.404'], ['B04.820.480.937.600.650.500.500'], ['D20.215.894.811'], ['G06.930'], ['E01.370.225.875.970', 'E05.200.875.970']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interleukin-6 induces keratin expression in intestinal epithelial cells: potential role of keratin-8 in interleukin-6-induced barrier function alterations. | Keratin 8 (K8) and keratin-18 (K18) are the major intermediate filament proteins in the intestinal epithelia. The regulation and function of keratin in the intestinal epithelia is largely unknown. In this study we addressed the role and regulation of K8 and K18 expression by interleukin 6 (IL-6). Caco2-BBE cell line an... | ['Animals', 'Caco-2 Cells', 'Colon', 'Epithelial Cells', 'Fluorescent Dyes', 'Humans', 'Inflammation', 'Interleukin-6', 'Intestines', 'Keratin-8', 'Keratins', 'Mice', 'Mice, Transgenic', 'Microscopy, Confocal', 'Permeability'] | 17,213,200 | [['B01.050'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['A11.436'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Toll-like receptor 9-mediated protection of enterovirus 71 infection in mice is due to the release of danger-associated molecular patterns. | Enterovirus 71 (EV71), a positive-stranded RNA virus, is the major cause of hand, foot, and mouth disease (HFMD) with severe neurological symptoms. Antiviral type I interferon (alpha/beta interferon [IFN-á/â]) responses initiated from innate receptor signaling are inhibited by EV71-encoded proteases. It is less well un... | ['Animals', 'Base Sequence', 'Cells, Cultured', 'Cytokines', 'DNA Primers', 'Enterovirus A, Human', 'Enterovirus Infections', 'Enzyme-Linked Immunosorbent Assay', 'Interferon Type I', 'Mice', 'Mice, Knockout', 'NF-kappa B', 'Real-Time Polymerase Chain Reaction', 'Toll-Like Receptor 9', 'Virus Replication'] | 25,078,697 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B04.820.578.750.284.180'], ['C01.925.782.687.359'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Zscan10 is dispensable for maintenance of pluripotency in mouse embryonic stem cells. | Zinc finger and SCAN domain-containing 10 (Zscan10, also known as Zfp206) encodes a transcription factor that has been reported to be involved in the maintenance of pluripotency in mouse embryonic stem (ES) cells. Here we generated inducible knockout ES cells for Zscan10 using the Cre-loxP system and analyzed its funct... | ['Animals', 'Cell Differentiation', 'Cell Proliferation', 'Cells, Cultured', 'Mice', 'Mouse Embryonic Stem Cells', 'Pluripotent Stem Cells', 'Transcription Factors'] | 26,592,664 | [['B01.050'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.872.700.250.875'], ['A11.872.700'], ['D12.776.930']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Brain vasculature and mitochondrial responses to ischemia in gerbils. I. Basic anatomical patterns and biochemical correlates. | A unique blood supply to the brain, the 'Circle of Willis' (COW), exists in all mammals except for the Mongolian gerbil (Meriones unguiculatus). This system is capable of compensating for a decrease in blood supply in one of the four arteries, which may occur during pathological conditions. The posterior connection bet... | ['Animals', 'Brain', 'Brain Ischemia', 'Circle of Willis', 'Disease Models, Animal', 'Fluorometry', 'Gerbillinae', 'Mitochondria', 'NAD', 'Oxidation-Reduction', 'Rats', 'Seizures'] | 1,486,485 | [['B01.050'], ['A08.186.211'], ['C10.228.140.300.150', 'C14.907.253.092'], ['A07.015.114.228.351'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.196.712.516.600'], ['B01.050.150.900.649.313.992.635.300'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D03.633.100.759.646.138.694', 'D08.211.589', 'D13.695... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ecogeographic patterns of rabies in southern Ontario based on time series analysis. | We describe a method based on time series analysis that divided the rabies enzootic area of southern Ontario into 13 regions using data collected at the township level, the smallest available geographical unit for Ontario (Canada). The intent was to discover ecogeographic patterns if such existed. For the period 1957-8... | ['Animals', 'Animals, Domestic', 'Animals, Wild', 'Cats', 'Cluster Analysis', 'Disease Transmission, Infectious', 'Dogs', 'Female', 'Foxes', 'Male', 'Mephitidae', 'Ontario', 'Periodicity', 'Population Surveillance', 'Rabies', 'Rabies Vaccines', 'Time Factors'] | 15,362,820 | [['B01.050'], ['B01.050.050.116'], ['B01.050.050.300'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['N06.850.335'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.150.900.649.313.750.250.216.250'], ['B01.050.150.900.649.313.750.250.479'], ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Prognostic role of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in patients with bone metastases. | BACKGROUND: Skeletal metastases are a common problem in patients with cancer, and surgical decision making depends on multiple factors including life expectancy. Identification of new prognostic factors can improve survival estimation and guide healthcare providers in surgical decision making. In this study, we aim to ... | ['Aged', 'Bone Neoplasms', 'Disease-Free Survival', 'Female', 'Humans', 'Lymphocyte Count', 'Male', 'Middle Aged', 'Neutrophils', 'Platelet Count', 'Prognosis', 'Retrospective Studies', 'Tertiary Care Centers'] | 30,116,026 | [['M01.060.116.100'], ['C04.588.149', 'C05.116.231'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.195.107.595.500', 'E01.370.225.625.107.595.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Factors Affecting Time NICU Nurses Spend With Fathers: Results From a Larger Study. | BACKGROUND: Father involvement in the neonatal intensive care unit (NICU) is important for outcomes of children and should be encouraged. Neonatal nurses have been identified as a major source of support for fathers; yet, nurses have identified obstacles to family-centered care of the father.PURPOSE: The purpose of thi... | ['Attitude of Health Personnel', 'Father-Child Relations', 'Fathers', 'Humans', 'Intensive Care Units, Neonatal', 'Nurses, Neonatal', 'Professional-Family Relations', 'Surveys and Questionnaires'] | 31,517,645 | [['F01.100.050', 'N05.300.100'], ['F01.829.263.370.290.110'], ['F01.829.263.500.320.100', 'I01.880.853.150.500.340.210', 'M01.620.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493.390.380'], ['M01.526.485.650.648.940.500', 'N02.360.650.648.940.500'], ['F01.829.401.550'], ['E05.318.308.980', 'N05... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Web-based general public opinion study of automated versus manual external chest compression. | BACKGROUND: Only a few cardiac-arrest victims receive external chest compression (ECC) by a bystander.OBJECTIVE: To test the hypothesis that the general public might start ECC more often if they used an automated device rather than a manual massage.METHODS: Web-based public opinion survey based on two short videos, one... | ['Adult', 'Cardiopulmonary Resuscitation', 'Female', 'First Aid', 'Heart Massage', 'Humans', 'Male', 'Middle Aged', 'Out-of-Hospital Cardiac Arrest', 'Public Opinion', 'Reproducibility of Results', 'Surveys and Questionnaires', 'Video Recording'] | 23,558,150 | [['M01.060.116'], ['E02.365.647.110'], ['E02.365.305'], ['E02.365.647.375', 'E04.100.376.458', 'E04.928.220.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.383.610'], ['I01.880.630.548'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Short-term international migration trends in England and Wales from 2004 to 2009. | Short-term migration estimates for England and Wales are the latest addition to the Office for National Statistics (ONS) migration statistics. This article discusses definitions of short-term migration and the methodology that is used to produce the estimates. Some of the estimates and the changes in the estimates over... | ['Continental Population Groups', 'Emigration and Immigration', 'England', 'Humans', 'Time Factors', 'Wales'] | 21,727,921 | [['M01.686.508'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.910.857'], ['Z01.542.363.914']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Did the 'croaky voice' public health campaign have any impact on the stage of laryngeal cancer at presentation in 84 cases from the Humber and Yorkshire Coast Cancer Network? | BACKGROUND: A public health campaign on laryngeal cancer was conducted in 2011 in the Humber and Yorkshire Coast Cancer Network. This study evaluated its subsequent impact (if any) upon the stage of laryngeal cancer at presentation.METHODS: Cases of laryngeal cancer diagnosed in the Humber and Yorkshire Coast Cancer Ne... | ['Aged', 'Early Detection of Cancer', 'Female', 'Health Promotion', 'Humans', 'Laryngeal Neoplasms', 'Male', 'Mass Screening', 'Middle Aged', 'Neoplasm Staging', 'Program Evaluation', 'Registries', 'Regression Analysis', 'Retrospective Studies', 'Time Factors', 'United Kingdom', 'Voice'] | 28,589,872 | [['M01.060.116.100'], ['E01.390.500'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481', 'C09.400.369', 'C09.647.481'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Effect of ectopic OCT4 expression on canine adipose tissue-derived mesenchymal stem cell proliferation. | Enhancing the proliferative capacity of mesenchymal stem cells (MSCs) is critical for increasing their therapeutic potential in a variety of diseases. We hypothesized that lentivirus-mediated overexpression of canine octamer-binding transcription factor 4 (OCT4) might influence the proliferation of canine adipose tissu... | ['Adipose Tissue', 'Animals', 'Antigens, CD', 'Cell Differentiation', 'Cell Proliferation', 'Cells, Cultured', 'Cyclin D1', 'Dogs', 'G2 Phase', 'Genetic Vectors', 'Lentivirus', 'Mesenchymal Stem Cells', 'Octamer Transcription Factor-3', 'Osteogenesis', 'S Phase'] | 24,797,505 | [['A10.165.114'], ['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D12.644.360.262.150.100', 'D12.776.167.218.150.100', 'D12.776.476.262.150.100', 'D12.776.624.664.700.100'], ['B01.050.150.900.649.313.750.250.216.200'], ['G04.144.500.340'], ['G... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term follow-up of reflux nephropathy in adults with vesicoureteral reflux--radiological and pathoanatomical analysis. | PURPOSE: To study the long-term development of urographic renal morphology in adults with vesicoureteral reflux, to investigate the relationship between renal damage and reflux grade, and to analyse the association between the long-term urographic outcome and the occurrence of acute pyelonephritis and reflux during fol... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Humans', 'Kidney', 'Kidney Diseases', 'Male', 'Middle Aged', 'Pyelonephritis', 'Urography', 'Vesico-Ureteral Reflux'] | 11,442,458 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['C12.777.419', 'C13.351.968.419'], ['M01.060.116.630'], ['C12.77... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
High Mobility Group B-1 (HMGB-1) Promotes Apoptosis of Macrophage-Derived Foam Cells by Inducing Endoplasmic Reticulum Stress. | BACKGROUND/AIMS: High mobility group B-1 (HMGB-1)-induced endoplasmic reticulum stress (ERS) has been implicated in inflammation and dendritic cell maturation. C/EBP-homologous protein (CHOP) is a vital component of ERS and apoptosis and plays a critical role in atherosclerosis. However, only a little information is av... | ['Animals', 'Apoptosis', 'Endoplasmic Reticulum Stress', 'Foam Cells', 'HMGB1 Protein', 'Heat-Shock Proteins', 'Lipoproteins, LDL', 'Macrophages', 'Mice', 'Oxidative Stress', 'RAW 264.7 Cells', 'Signal Transduction', 'Transcription Factor CHOP'] | 30,041,247 | [['B01.050'], ['G04.146.954.035'], ['G04.434'], ['A11.329.372.368', 'A11.627.482.368', 'A11.733.397.368', 'A15.382.670.522.368', 'A15.382.680.397.368'], ['D12.776.260.356.300', 'D12.776.660.235.400.600.300', 'D12.776.664.235.400.600.300'], ['D12.776.580.216'], ['D10.532.515', 'D12.776.521.550'], ['A11.329.372', 'A11.62... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Solvent deuterium isotope effects on phosphodiester cleavage catalyzed by an extraordinarily active Zn(II) complex. | The effect of increasing pL on the extraordinary catalytic activity of a dinuclear Zn2+ complex toward cleavage of uridine 3'-4-nitrophenyl phosphate (UpPNP) in H2O and D2O was determined. This change from H2O to D2O causes an increase from 7.8 to 8.4 in the apparent pKa of a catalytic functional group, but has little ... | ['Catalysis', 'Deuterium Exchange Measurement', 'Kinetics', 'Organometallic Compounds', 'Organophosphates', 'Potentiometry', 'RNA', 'Water', 'Zinc'] | 15,669,821 | [['G02.130'], ['E05.196.344'], ['G01.374.661', 'G02.111.490'], ['D02.691'], ['D02.705.400'], ['E05.196.922.750', 'E05.301.710'], ['D13.444.735'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925'], ['D01.268.556.940', 'D01.268.956.906', 'D01.552.544.940']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury. | We have tested whether small intraischemic variations in brain temperature influence the outcome of transient ischemia. To measure brain temperature, a thermocouple probe was placed stereotaxically into the left dorsolateral striatum of rats prior to 20 min of four-vessel occlusion. Rectal temperature was maintained at... | ['Adenosine Triphosphate', 'Animals', 'Body Temperature', 'Brain', 'Cerebral Cortex', 'Cerebrovascular Circulation', 'Corpus Striatum', 'Energy Metabolism', 'Glucose', 'Hippocampus', 'Ischemic Attack, Transient', 'Male', 'Neurons', 'Phosphocreatine', 'Pyruvates', 'Pyruvic Acid', 'Rats', 'Rats, Inbred Strains', 'Thalamu... | 3,693,428 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['A08.186.211'], ['A08.186.211.200.885.287.500'], ['G09.330.100.159'], ['A08.186.211.200.885.287.249.487'], ['G03.295'], ['D09.947.875.359.448'], ['A08.186.211.180.405', 'A08.186.211.200.885.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sex differences in quadriceps rate of torque development within 1 year of ACL reconstruction. | OBJECTIVES: To investigate the effect of sex on measures of quadriceps strength, rate of torque development, and knee function during the first year following ACLR.DESIGN: Cross-sectional; SETTING: University community; PARTICIPANTS: Sixty individuals (29 men) with unilateral ACLR in the last 12 months.MAIN OUTCOME MEA... | ['Adolescent', 'Adult', 'Anterior Cruciate Ligament Reconstruction', 'Cross-Sectional Studies', 'Exercise Therapy', 'Female', 'Follow-Up Studies', 'Humans', 'Isometric Contraction', 'Knee Joint', 'Male', 'Muscle Strength', 'Muscle Weakness', 'Quadriceps Muscle', 'Sex Factors', 'Time Factors', 'Young Adult'] | 31,042,614 | [['M01.060.057'], ['M01.060.116'], ['E04.555.110.026', 'E04.680.101.026'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.15... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inhibition of cell growth and induction of G1-phase cell cycle arrest in hepatoma cells by steroid extract from Meretrix meretrix. | In this study, we report that the steroid extract 5alpha, 8alpha-epidioxycholest-6-ene-3beta-ol (MME) from Meretrix meretrix has the ability to inhibit growth of hepatoma cells and to induce G1-phase cell cycle arrest in two human hepatoma cell lines, HepG2 and Hep3B. HepG2 cells were more sensitive than Hep3B to MME. ... | ['Bivalvia', 'Carcinoma, Hepatocellular', 'Cell Line, Tumor', 'Cell Proliferation', 'Cyclin-Dependent Kinase Inhibitor p16', 'Cyclin-Dependent Kinase Inhibitor p21', 'Cyclin-Dependent Kinase Inhibitor p27', 'G1 Phase', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Liver Neoplasms', 'Steroids', 'Tumor Supp... | 16,458,116 | [['B01.050.500.644.080'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.644.360.225.200', 'D12.776.167.187.200', 'D12.776.476.225.200', 'D12.776.624.776.355.200'], ['D12.644.360.225.500', 'D... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Charcot-Marie-Tooth disease]. | Charcot-Marie-Tooth (CMT) disease, also known as peroneal muscular atrophy or hereditary motor and sensory neuropathy, is among the most frequent hereditary disorders of the nervous system. The relatively homogeneous clinical phenotype involves mainly progressive weakness and wasting of distal muscles; it starts and pr... | ['Axons', 'Charcot-Marie-Tooth Disease', 'Demyelinating Diseases', 'Disease Progression', 'Electrophysiology', 'Genes, Dominant', 'Genes, Recessive', 'Humans', 'Muscle, Skeletal', 'Phenotype', 'Proteins'] | 19,135,335 | [['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['C10.500.300.200', 'C10.574.500.495.200', 'C10.668.829.800.300.200', 'C16.131.666.300.200', 'C16.320.400.375.200'], ['C10.314'], ['C23.550.291.656'], ['H01.158.344.528', 'H01.158.782.236'], ['G05.360.340.024.340.240', 'G05.420.320'], ['G05.360.... | ['Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Flow cytometric electronic direct current volume and radiofrequency impedance measurements of single cells and particles. | A flow-system instrument is described that uses direct current and radiofrequency (rf) currents to detect simultaneously the low and high frequency impedance changes produced by biologic cells or particles suspended in saline traversing through a 93um diameter sensing orifice. For nonmembranous particles and plastic mi... | ['Animals', 'Cell Cycle', 'Cell Line', 'Cricetinae', 'Cricetulus', 'Dactinomycin', 'Electric Conductivity', 'Electronics', 'Flow Cytometry', 'Microspheres'] | 7,273,970 | [['B01.050'], ['G04.144'], ['A11.251.210'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['D03.633.300.200', 'D04.345.566.252', 'D12.644.641.252'], ['G01.358.500.249.277'], ['H01.671.293'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Heteroduplex DNA correction in Saccharomyces cerevisiae is mismatch specific and requires functional PMS genes. | In vitro-constructed heteroduplex DNAs with defined mismatches were corrected in Saccharomyces cerevisiae cells with efficiencies that were dependent on the mismatch. Single-nucleotide loops were repaired very efficiently; the base/base mismatches G/T, A/C, G/G, A/G, G/A, A/A, T/T, T/C, and C/T were repaired with a hig... | ['Alleles', 'Base Sequence', 'DNA Repair', 'DNA, Fungal', 'Mutation', 'Nucleic Acid Conformation', 'Nucleic Acid Heteroduplexes', 'Plasmids', 'Saccharomyces cerevisiae', 'Transfection'] | 2,685,551 | [['G05.360.340.024.340.030'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.222', 'G05.219'], ['D13.444.308.300'], ['G05.365.590'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.444.500'], ['G05.360.600'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['E05.393.350.810', 'G05.728.860']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Design and Use of an Apparatus for Presenting Graspable Objects in 3D Workspace. | Reaching and grasping are highly-coupled movements, and their underlying neural dynamics have been widely studied in the last decade. To distinguish reaching and grasping encodings, it is essential to present different object identities independent of their positions. Presented here is the design of an automatic appara... | ['Biomechanical Phenomena', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Male', 'Psychomotor Performance'] | 31,449,242 | [['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['F02.808', 'G11.427.700', 'G11.561.660']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cigarette Smoke and Estrogen Signaling in Human Airway Smooth Muscle. | AIMS: Cigarette smoke (CS) in active smokers and second-hand smoke exposure exacerbate respiratory disorders such as asthma and chronic bronchitis. While women are known to experience a more asthmatic response to CS than emphysema in men, there is limited information on the mechanisms of CS-induced airway dysfunction. ... | ['Bronchoconstriction', 'Calcium', 'Complex Mixtures', 'Cyclic AMP', 'Estradiol', 'Estrogen Receptor alpha', 'Female', 'Gene Expression Regulation', 'Histamine', 'Humans', 'Membrane Proteins', 'Muscle, Smooth', 'Myocytes, Smooth Muscle', 'Neoplasm Proteins', 'Phosphorylation', 'Primary Cell Culture', 'Respiratory Syste... | 26,113,109 | [['G09.772.705.700.080'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D20'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D12.776.826.750.350.174'], ['G05.308'], ['D02.092.211.215.501', 'D02.092.4... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
PREPmate automated processor: comparison of automated and manual methods of liquid-based gynecologic sample preparation. | The development of procedures for fully automated processing of liquid-based gynecologic samples has been the focus of considerable interest to the cytology laboratory. Liquid-based collection and processing technology has been shown to improve sample adequacy, resulting in an overall improvement in quality of sample p... | ['Automation', 'Carcinoma, Squamous Cell', 'Cervical Intraepithelial Neoplasia', 'Endometrium', 'Epithelial Cells', 'Female', 'Genital Neoplasms, Female', 'Histocytological Preparation Techniques', 'Humans', 'Reproducibility of Results', 'Uterine Cervical Dysplasia'] | 12,412,000 | [['J01.897.104'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.557.470.200.240.250'], ['A05.360.319.679.490'], ['A11.436'], ['C04.588.945.418', 'C13.351.937.418'], ['E01.370.225.500.620', 'E01.370.225.750.600', 'E05.200.500.620', 'E05.200.750.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.37... | ['Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Sperm analysis by flow cytometry using the fluorescent thiol labeling agent monobromobimane. | The fluorescent labeling agent monobromobimane (mBBr) was used to label thiols and disulfides (after reduction of sperm disulfides by dithiothreitol) in intact spermatozoa. Bimane-labeled sperm of several mammalian species were analyzed by flow cytometry (FCM) and examined by fluorescent microscopy. FCM analysis showed... | ['Animals', 'Bridged Bicyclo Compounds', 'Disulfides', 'Flow Cytometry', 'Fluorescent Dyes', 'Male', 'Mice', 'Mice, Inbred ICR', 'Rats', 'Rats, Inbred Strains', 'Sperm Maturation', 'Spermatozoa', 'Sulfhydryl Compounds'] | 1,931,044 | [['B01.050'], ['D02.455.426.100.080', 'D04.075.080'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['D27.720.233.348', 'D27... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The selective alpha7 agonist GTS-21 attenuates cytokine production in human whole blood and human monocytes activated by ligands for TLR2, TLR3, TLR4, TLR9, and RAGE. | The cholinergic antiinflammatory pathway modulates inflammatory cytokine production through a mechanism dependent on the vagus nerve and the alpha7 subunit of the nicotinic acetylcholine receptor. GTS-21 [3-(2,4-dimethoxybenzylidene) anabaseine], a selective alpha7 agonist, inhibits inflammatory cytokine production in ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Benzylidene Compounds', 'Cell Survival', 'Cells, Cultured', 'Cholinergic Agonists', 'Cytokines', 'Endotoxins', 'Female', 'Gene Expression', 'Humans', 'Interleukin-1beta', 'Male', 'Middle Aged', 'Monocytes', 'Nicotine', 'Pyridines', 'Receptor for Advanced Glycation End Products', ... | 19,593,403 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D02.455.426.559.389.150'], ['G04.346'], ['A11.251'], ['D27.505.519.625.120.140', 'D27.505.696.577.120.140'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D23.946.123.329'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Itraconazole for treatment of fungal infections in patients undergoing allogeneic hematopoietic stem cell transplantation]. | OBJECTIVE: To investigate the effect of intravenous itraconazole on fungal infections in patients undergoing allogeneic hematopoietic stem cell transplantation.METHODS: Seventy-five such patients treated with itraconazole from October, 2002 to October, 2005 were studied. The diagnosis of fungal infection was made accor... | ['Adolescent', 'Adult', 'Antifungal Agents', 'Child', 'Female', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Itraconazole', 'Male', 'Middle Aged', 'Mycoses', 'Transplantation, Homologous'] | 17,331,384 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.136'], ['M01.060.406'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.799.550', 'D03.383.606.530'], ['M01.060.116.630'], ['C01.150.703'], ['E04.936.864']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[New possibilities in treatment and rehabilitation of alcohol-dependent patients--a catamnestic study on the efficiency of outpatient treatment programmes demonstrated by a model procedure]. | First results of a clinical and catamnestic investigation are reported for the efficiency of a highly structured outpatient therapy with alcohol-dependents. One hundred and two patients were included in the study. Of the patients,60% were male and 40% female. The average age was 45 years (+/-8). The average duration of... | ['Adult', 'Alcoholism', 'Ambulatory Care', 'Female', 'Follow-Up Studies', 'Germany', 'Humans', 'Male', 'Middle Aged', 'Outcome and Process Assessment, Health Care', 'Patient Dropouts', 'Prospective Studies', 'Psychotherapy', 'Retreatment', 'Risk Factors', 'Secondary Prevention', 'Temperance'] | 12,627,237 | [['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['E02.760.106', 'N02.421.585.106'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N04.761.559', 'N05.715.360.575'], ['F01.100.15... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Adrenomedullin promotes proliferation and migration of cultured endothelial cells. | Adrenomedullin (AM) is a vasoactive hormone which exerts its action through cyclic adenosine monophosphate(cAMP) /cAMP-dependent protein kinase (PKA) cascade and intracellular Ca2+ mobilization. Recently, evidence has accumulated that AM plays a critical role in the regulation of vascular tone, remodeling and morphogen... | ['Adrenomedullin', 'Cell Division', 'Cell Movement', 'Cells, Cultured', 'Cyclic AMP', 'Cyclic AMP-Dependent Protein Kinases', 'Endothelium, Vascular', 'Humans', 'Neovascularization, Physiologic', 'Peptides', 'Umbilical Veins', 'Vasodilator Agents'] | 12,630,817 | [['D06.472.699.077', 'D12.644.548.017'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Passivation of black phosphorus as organic-phase enzyme platform for bisphenol A determination. | Black phosphorus (BP) has a high charge-carrier mobility (?1000 cm2 V-1 s-1), but the bare BP degrades rapidly in the presence of oxygen and water which limits the application of the BP. In this study, a simple, non-covalent passivation strategy is developed by modifying of the BP with hexamethylendiamine (HA). The fun... | ['Benzhydryl Compounds', 'Benzoquinones', 'Biosensing Techniques', 'Diamines', 'Electrochemical Techniques', 'Electrodes', 'Endocrine Disruptors', 'Enzymes, Immobilized', 'Limit of Detection', 'Monophenol Monooxygenase', 'Phenols', 'Phosphorus', 'Reproducibility of Results'] | 31,864,622 | [['D02.455.426.559.389.115'], ['D02.806.250'], ['E05.601.043'], ['D02.092.782.258'], ['E05.301'], ['E07.305.250'], ['D27.505.696.353', 'D27.888.141'], ['D08.811.180', 'D12.776.463.500'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['D08.811.682.690.708.125.500'], ['D02.455.426.559.389... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Inhibition of p38 MAPK signaling augments skin tumorigenesis via NOX2 driven ROS generation. | p38 mitogen-activated protein kinases (MAPKs) respond to a wide range of extracellular stimuli. While the inhibition of p38 signaling is implicated in the impaired capacity to repair ultraviolet (UV)-induced DNA damage-a primary risk factor for human skin cancers-its mechanism of action in skin carcinogenesis remains u... | ['Animals', 'Carcinogenesis', 'Carcinoma, Squamous Cell', 'Cell Line, Tumor', 'Cell Proliferation', 'Cells, Cultured', 'Gene Expression Regulation, Enzymologic', 'Humans', 'Imidazoles', 'Keratinocytes', 'MAP Kinase Signaling System', 'Membrane Glycoproteins', 'Mice', 'Mice, Knockout', 'Microarray Analysis', 'NADPH Oxid... | 24,824,222 | [['B01.050'], ['C04.697.098', 'C23.550.727.098'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['G05.308.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.308'], ['A11.409.500', 'A11.436.397'], ['G02.111.... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Vaccination of turkeys with cell-free culture filtrate of Pasteurella multocida. | Turkeys given cell-free culture filtrate (CCF) of Pasteurella multocida strain R44/6 orally, via air sacs, or subcutaneously mixed 1:1 with incomplete Freund's adjuvant (IFA) at 6 and 9.5 weeks of age were compared with negative controls given bacteriologic medium and positive controls vaccinated with a commercial bact... | ['Administration, Oral', 'Air Sacs', 'Animals', 'Antibodies, Bacterial', 'Bacterial Vaccines', 'Body Weight', 'Female', 'Injections, Subcutaneous', 'Male', 'Pasteurella', 'Pasteurella Infections', 'Poultry Diseases', 'Sex Factors', 'Turkeys', 'Vaccination'] | 2,029,246 | [['E02.319.267.100'], ['A13.048'], ['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D20.215.894.135'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E02.319.267.530.620'], ['B03.440.450.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Cognitive performance in schizophrenia (paranoid vs residual subtype)]. | INTRODUCTION: Several studies refer to the relationship between schizophrenia and cognitive dysfunctions. The most frequent disturbances accepted are the deficits in the executive, memory and verbal tests. However, there are few comparative data about the cognitive functioning of the different subtypes of schizophrenia... | ['Adult', 'Cognition Disorders', 'Female', 'Humans', 'Male', 'Middle Aged', 'Schizophrenia', 'Schizophrenia, Paranoid'] | 17,643,135 | [['M01.060.116'], ['F03.615.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.700.750'], ['F03.700.750.600']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
All-Bond--fourth generation dentin bonding system. | The All-Bond system is a unique development in the field of adhesive dentistry. It is a universal bonding system that will bond composite to all dental-related surfaces: dentin, enamel, metal alloy (precious and nonprecious), amalgam, porcelain, and composite. It is also the only system that allows use of both the cons... | ['Composite Resins', 'Dental Alloys', 'Dental Bonding', 'Dental Cements', 'Dental Enamel', 'Dental Porcelain', 'Dentin', 'Humans', 'Methacrylates', 'Smear Layer'] | 1,817,583 | [['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['D25.339.208', 'J01.637.051.339.208'], ['E06.095'], ['D25.339.291', 'J01.637.051.339.291'], ['A14.549.167.900.255'], ['D25.339.376', 'J01.637.051.339.376', 'J01.637.153.377'], ['A14.549.167.900... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Do plain films of the chest and abdomen have a role in the diagnosis of acute pancreatitis? | Radiographs taken on the day of admission on 52 patients with acute pancreatitis have been compared with similar radiographs of 30 patients with acute cholecystitis and 22 patients with perforated duodenal ulcer. Two radiologists, who were unaware of the clinical features, looked specifically for the presence of 30 rad... | ['Acute Disease', 'Adult', 'Aged', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pancreatitis', 'Radiography, Abdominal', 'Radiography, Thoracic'] | 6,825,395 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C06.689.750'], ['E01.370.350.700.715'], ['E01.370.350.700.730']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
DNP-specific/class I MHC-restricted suppressor molecules bear determinants of the T cell receptor alpha- and beta-chains. The V beta 8+ chain dictates restriction to either K or D. | To examine in greater detail the relationship between DNP-specific/class I MHC-restricted suppressor molecules (SSF) that inhibit contact sensitivity to 2,4-dinitrofluorobenzene and the receptors on the T cells that produce them, we have generated two T cell hybridomas that can be induced to produce and secrete these m... | ['Animals', 'Dinitrobenzenes', 'Epitopes', 'H-2 Antigens', 'Hybridomas', 'Macromolecular Substances', 'Major Histocompatibility Complex', 'Mice', 'Mice, Inbred Strains', 'Receptors, Antigen, T-Cell', 'Receptors, Antigen, T-Cell, alpha-beta', 'Suppressor Factors, Immunologic', 'T-Lymphocytes, Regulatory'] | 1,697,873 | [['B01.050'], ['D02.455.426.559.389.565.225', 'D02.640.529.240'], ['D23.050.550'], ['D23.050.301.500.100.350', 'D23.050.301.500.400.199', 'D23.050.705.552.100.350', 'D23.050.705.552.410.199'], ['A11.251.353.485', 'A11.251.600.485'], ['D05'], ['G05.360.340.024.340.610', 'G05.360.340.024.380.500', 'G12.500.500'], ['B01.0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
ATP activates both receptor and sustentacular supporting cells in the olfactory epithelium of Xenopus laevis tadpoles. | Nucleotides and amino acids are acknowledged categories of water-borne olfactory stimuli. In previous studies it has been shown that larvae of Xenopus laevis are able to sense amino acids. Here we report on the effect of ATP in the olfactory epithelium (OE) of Xenopus laevis tadpoles. First, ATP activates a subpopulati... | ['Adenosine Triphosphate', 'Amino Acids', 'Aniline Compounds', 'Animals', 'Biotin', 'Calcium', 'Calnexin', 'Colforsin', 'Dextrans', 'Diagnostic Imaging', 'Electric Stimulation', 'Epithelial Cells', 'Immunohistochemistry', 'In Vitro Techniques', 'Membrane Potentials', 'Odorants', 'Olfactory Mucosa', 'Olfactory Receptor ... | 16,420,422 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D12.125'], ['D02.092.146'], ['B01.050'], ['D03.383.129.308.080', 'D08.211.096'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.644.360.372.311', 'D12.776.157.125.412.311', 'D12.776.476.387.311', 'D12.776.503.295', 'D12.776.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Gene flow in Dubautia arborea and D. ciliolata: the roles of ecology and isolation by distance in maintaining species boundaries despite ongoing hybridization. | The relative roles of gene flow and natural selection in maintaining species differentiation have been a subject of debate for some time. The traditional view is that gene flow constrains adaptive divergence and maintains species cohesiveness. Alternatively, ecological speciation posits that the reverse is true: that a... | ['Adaptation, Biological', 'Asteraceae', 'Ecosystem', 'Gene Flow', 'Genetic Markers', 'Hybridization, Genetic', 'Microsatellite Repeats', 'Plant Leaves', 'Selection, Genetic', 'Species Specificity'] | 17,894,757 | [['G16.012'], ['B01.650.940.800.575.912.250.100'], ['G16.500.275.157', 'N06.230.124'], ['G05.330.159'], ['D23.101.387', 'G05.695.450'], ['E05.820.150.390', 'G05.090.390'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500'], ['A18.024.812'], ['G05.783'], ['G16.824']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Herpes simplex virus encephalitis. Prolonged intrathecal IgG synthesis and cellular activity in the cerebrospinal fluid with transient impairment of blood-brain barrier. | Alterations of cerebrospinal fluid (CFS) proteins and cells and blood-brain barrier impairment were determined in 4 patients with proven and 2 patients with presumptive herpes simplex virus encephalitis ( HSVE ) using simultaneous nephelometric measurements of CSF and serum albumin and immunoglobulins and combined Mill... | ['Adult', 'Aged', 'Blood-Brain Barrier', 'Cerebrospinal Fluid', 'Encephalitis', 'Female', 'Follow-Up Studies', 'Herpes Simplex', 'Humans', 'Immunoglobulin A', 'Immunoglobulin G', 'Immunoglobulin M', 'Leukocyte Count', 'Male', 'Middle Aged', 'Serum Albumin'] | 6,726,275 | [['M01.060.116'], ['M01.060.116.100'], ['A07.035', 'A08.186.211.035'], ['A12.207.270.210'], ['C10.228.140.430'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C01.925.256.466.382', 'C01.925.825.320', 'C17.800.838.790.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A comparison of plasmapheresis versus high-dose IVIG desensitization in renal allograft recipients with high levels of donor specific alloantibody. | Several protocols allow for the successful transplantation of sensitized renal allograft recipients, yet no one best method has emerged. The aim of the current study was to compare the efficacy of high-dose IVIG with two different plasmapheresis (PP)-based regimens in kidney transplant recipients with high levels of do... | ['Adult', 'Female', 'Flow Cytometry', 'Graft Survival', 'Histocompatibility Testing', 'Humans', 'Immunoglobulins, Intravenous', 'Immunosuppressive Agents', 'Isoantibodies', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Minnesota', 'Plasmapheresis', 'Retrospective Studies', 'Survival Analysis', 'Transplantation, Hom... | 16,426,319 | [['M01.060.116'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['G12.875.545.340'], ['E01.370.225.812.385', 'E05.200.812.385', 'E05.478.594.385'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Genotype, development and tissue-derived variation of cell-wall properties in the lignocellulosic energy crop Miscanthus. | BACKGROUND AND AIMS: Species and hybrids of the genus Miscanthus contain attributes that make them front-runners among current selections of dedicated bioenergy crops. A key trait for plant biomass conversion to biofuels and biomaterials is cell-wall quality; however, knowledge of cell-wall composition and biology in M... | ['Biofuels', 'Biomass', 'Carbohydrate Metabolism', 'Cell Wall', 'Ethanol', 'Genotype', 'Lignin', 'Phenotype', 'Plant Leaves', 'Plant Stems', 'Poaceae', 'Spectroscopy, Fourier Transform Infrared'] | 24,737,720 | [['D20.147', 'N06.230.132.644.124'], ['G16.500.275.157.100', 'N06.230.124.100'], ['G02.111.158', 'G03.191'], ['A11.284.183'], ['D02.033.375'], ['G05.380'], ['D05.750.078.562.180.515', 'D05.750.078.687', 'D20.538', 'D25.720.099.687', 'J01.637.051.720.099.687'], ['G05.695'], ['A18.024.812'], ['A18.024.937'], ['B01.650.94... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Antipsychotic drug effects on left prefrontal phospholipid metabolism: a follow-up 31P-2D-CSI study of haloperidol and risperidone in acutely ill chronic schizophrenia patients. | INTRODUCTION: ³?Phosphorous magnetic resonance spectroscopy (2D chemical shift imaging, CSI) allows multiregional study of membrane phospholipids and high-energy phosphates in vivo. Increased membrane lipid turnover and impaired energy supply have repeatedly been shown in first-episode schizophrenia patients, and might... | ['Adult', 'Antipsychotic Agents', 'Basal Ganglia', 'Cerebellum', 'Cerebral Cortex', 'Female', 'Haloperidol', 'Humans', 'Lipid Metabolism', 'Magnetic Resonance Spectroscopy', 'Male', 'Membrane Lipids', 'Middle Aged', 'Phospholipids', 'Phosphorus Isotopes', 'Risperidone', 'Schizophrenia'] | 22,516,552 | [['M01.060.116'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['A08.186.211.200.885.287.249'], ['A08.186.211.132.810.428.200'], ['A08.186.211.200.885.287.500'], ['D02.522.352.506'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.458'], ['E05.196.867.519'], ['D10.57... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The heterotrimeric Thermus thermophilus Asp-tRNA(Asn) amidotransferase can also generate Gln-tRNA(Gln). | Thermus thermophilus strain HB8 is known to have a heterodimeric aspartyl-tRNA(Asn) amidotransferase (Asp-AdT) capable of forming Asn-tRNA(Asn) [Becker, H.D. and Kern, D. (1998) Proc. Natl. Acad. Sci. USA 95, 12832-12837]. Here we show that, like other bacteria, T. thermophilus possesses the canonical set of amidotrans... | ['Amino Acid Sequence', 'Cloning, Molecular', 'Escherichia coli', 'Genes, Bacterial', 'Molecular Sequence Data', 'Nitrogenous Group Transferases', 'Protein Structure, Quaternary', 'RNA, Bacterial', 'RNA, Transfer, Amino Acyl', 'Recombinant Proteins', 'Sequence Deletion', 'Substrate Specificity', 'Thermus thermophilus'] | 10,913,601 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.220'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['L01.453.245.667'], ['D08.811.913.477'], ['G02.111.570.820.709.550'], ['D13.444.735.473'], ['D12.125.780', 'D13.44... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Middle-molecular hydroxyethyl starch as a volume substitute. Its rheological effect in peripheral arterial occlusive diseases]. | The tolerance to and effectiveness of middle-molecular hydroxy-ethyl starch as volume replacement by isovolemic haemodilution over 6 weeks was tested in 15 patients with peripheral arterial obstructive disease, stages II and III. After 6 weeks of isovolemic haemodilution treatment the pain-free walking distance increas... | ['Arterial Occlusive Diseases', 'Blood Viscosity', 'Drug Evaluation', 'Female', 'Gait', 'Hemodilution', 'Humans', 'Hydroxyethyl Starch Derivatives', 'Male', 'Middle Aged', 'Molecular Weight', 'Plasma Substitutes', 'Starch', 'Time Factors'] | 6,209,081 | [['C14.907.137'], ['G09.188.370.124', 'G09.330.380.630.110'], ['E05.290.625', 'E05.337.425'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['E02.514'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.301.915.500', 'D09.698.365.855.500'], ['M01.060.116.630'], ['G02.494'], ['D27.505.954.502.140.500'], ['D05.750... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effects of ACE inhibitor therapy on left ventricular myocardial mass and diastolic filling in previously untreated hypertensive patients: a cine MRI study. | Cardiac remodeling in case of hypertension induces hypertrophy of myocytes and elevated collagen content and, subsequently, impaired diastolic filling of the left ventricle. The purpose of this prospective study was to evaluate changes of left ventricular (LV) myocardial mass, as well as diastolic filling properties, i... | ['Adult', 'Aged', 'Angiotensin-Converting Enzyme Inhibitors', 'Cardiac Volume', 'Diastole', 'Female', 'Follow-Up Studies', 'Fosinopril', 'Heart Ventricles', 'Hemodynamics', 'Humans', 'Hypertension', 'Hypertrophy, Left Ventricular', 'Magnetic Resonance Imaging, Cine', 'Male', 'Middle Aged', 'Myocardium', 'Prospective St... | 11,436,209 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.389.745.085'], ['G09.330.380.249'], ['G09.330.580.295', 'G11.427.494.554.250', 'G11.427.494.570.295'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D02.705.629.500', 'D12.125.072.401.623.374'], ['A07.541.560'], ['G09.33... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Method to localise myocardial infarction using magnetocardiography: simulation studies. | The work presents a method for localising regions of myocardial infarction (MI) using magnetocardiography, which is validated by simulation techniques. We have verified that the first two principal components of magnetocardiographic signals obtained from torso mapping within a normal group are very similar even in expe... | ['Computer Simulation', 'Humans', 'Magnetics', 'Myocardial Infarction', 'Signal Processing, Computer-Assisted'] | 2,601,453 | [['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.671.493'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['L01.224.800']] | ['Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Somatostatin Analogue Treatment of a TSH-Secreting Adenoma Presenting With Accelerated Bone Metabolism and a Pericardial Effusion: A Case Report. | Increased bone turnover and other less frequent comorbidities of hyperthyroidism, such as heart failure, have only rarely been reported in association with central hyperthyroidism due to a thyrotropin (TSH)-secreting pituitary adenoma (TSHoma). Treatment is highly empirical and relies on eliminating the tumor and the h... | ['Adenoma', 'Adult', 'Antineoplastic Agents, Hormonal', 'Bone Diseases, Metabolic', 'Humans', 'Male', 'Octreotide', 'Pericardial Effusion', 'Pituitary Neoplasms', 'Thyrotropin'] | 26,765,410 | [['C04.557.470.035'], ['M01.060.116'], ['D27.505.954.248.169'], ['C05.116.198', 'C18.452.104'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.345.566.650', 'D12.644.641.650'], ['C14.280.695'], ['C04.588.322.609', 'C04.588.614.250.195.885.500.600', 'C10.228.140.211.885.500.600', 'C10.228.140.617.477.600', 'C10.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Estimated mortality of adult HIV-infected patients starting treatment with combination antiretroviral therapy. | OBJECTIVE: To provide estimates of mortality among HIV-infected patients starting combination antiretroviral therapy.METHODS: We report on the death rates from 122 925 adult HIV-infected patients aged 15 years or older from East, Southern and West Africa, Asia Pacific and Latin America. We use two methods to adjust for... | ['Adolescent', 'Adult', 'Africa', 'Age Factors', 'Anti-HIV Agents', 'Antiretroviral Therapy, Highly Active', 'Asia', 'CD4 Lymphocyte Count', 'Epidemiologic Methods', 'Female', 'HIV Infections', 'Humans', 'Latin America', 'Male', 'Middle Aged', 'Sex Factors', 'Survival Analysis', 'Young Adult'] | 23,172,344 | [['M01.060.057'], ['M01.060.116'], ['Z01.058'], ['N05.715.350.075', 'N06.850.490.250'], ['D27.505.954.122.388.077.088'], ['E02.319.310.075'], ['Z01.252'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Major venous anomalies and abdominal aortic surgery. | Patients with an infrarenal venous anomaly are relatively rare, but are most likely to suffer bleeding from an injury during abdominal aortic surgery. During the last five years, we have performed nine abdominal aortic surgeries with major venous anomalies. There was no severe haemorrhage and actually, after 3-53 month... | ['Aged', 'Aged, 80 and over', 'Aorta, Abdominal', 'Aortic Diseases', 'Aortography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Phlebography', 'Postoperative Hemorrhage', 'Renal Veins', 'Time Factors', 'Tomography, X-Ray Computed', 'Treatment Outcome', 'Vascular Surgical Procedures', 'Vena Cava, Inferior'] | 20,080,533 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A07.015.114.056.205'], ['C14.907.109'], ['E01.370.350.700.060.070', 'E01.370.370.050.070'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700.060.600', 'E01.370.370.050.600'], ['C23.550.414.941', 'C23.550.767.850'], ['A07.015.908.752... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In vitro characterization of calcium transport along the gastrointestinal tract of freshwater rainbow trout Oncorhynchus mykiss. | Using an in vitro gut-sac technique, this study examined the mechanisms of calcium (Ca) uptake along the gastrointestinal tract (GIT) of rainbow trout Oncorhynchus mykiss. Ca uptake into three different compartments (mucous-bound, mucosal epithelium and blood space) of four distinct GIT segments (stomach, anterior inte... | ['Animals', 'Biological Transport', 'Cadmium', 'Calcium', 'Gastrointestinal Tract', 'Gills', 'Kinetics', 'Oncorhynchus mykiss'] | 22,747,801 | [['B01.050'], ['G03.143'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A03.556'], ['A13.421'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.493.817.750.825.580.600']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
HLA and hypocretin studies in Korean patients with narcolepsy. | STUDY OBJECTIVES: Very few studies have evaluated narcolepsy in Asian countries, outside of Japan. Our goal was to study narcolepsy at the genetic, clinical and pathophysiological level in Korea.DESIGN: Prospective study of consecutive patients and age matched controls. Clinical data ascertained from the Stanford Sleep... | ['Adolescent', 'Adult', 'Carrier Proteins', 'Child', 'Female', 'HLA Antigens', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Korea', 'Male', 'Narcolepsy', 'Neuropeptides', 'Orexins', 'Prospective Studies'] | 12,071,546 | [['M01.060.057'], ['M01.060.116'], ['D12.776.157'], ['M01.060.406'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360', 'D12.776.476'], ['Z01.252.474.557', 'Z01.586.407'], ['C10.886.425.800.200.750', 'F03.870.400.800.200.750'], ['D12.644.400', 'D12.776.631.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Integrating microRNA and mRNA expression profiling in Symbiodinium microadriaticum, a dinoflagellate symbiont of reef-building corals. | BACKGROUND: Animal and plant genomes produce numerous small RNAs (smRNAs) that regulate gene expression post-transcriptionally affecting metabolism, development, and epigenetic inheritance. In order to characterize the repertoire of endogenous smRNAs and potential gene targets in dinoflagellates, we conducted smRNA and... | ['Animals', 'Anthozoa', 'Coral Reefs', 'Dinoflagellida', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Gene Ontology', 'MicroRNAs', 'Photosynthesis', 'RNA, Messenger', 'Symbiosis', 'Transcriptome'] | 24,119,094 | [['B01.050'], ['B01.050.500.308.237'], ['G16.500.275.157.130', 'N06.230.124.130'], ['B01.043.214'], ['E05.393.332'], ['G05.308'], ['H01.158.273.343.249.099', 'H01.770.644.145.350.124', 'L01.224.050.375.480.500.500', 'L01.313.500.750.300.550.500.500', 'L01.453.245.945.079.500'], ['D13.150.650.319', 'D13.444.735.150.319'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Visualization of rotator cuff tear morphology by radial magnetic resonance imaging. | The objective of this study was to investigate whether rotator cuff tear morphology could be visualized using radial MRI. We retrospectively investigated 52 shoulders that underwent preoperative MRI and arthroscopy for a complete rotator cuff tear. The tear length and width were measured using oblique coronal, axial, a... | ['Aged', 'Arthroscopy', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Retrospective Studies', 'Rotator Cuff', 'Rotator Cuff Injuries'] | 29,715,640 | [['M01.060.116.100'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Grape seed proanthocyanidin extract (GSPE) attenuates collagen-induced arthritis. | To examine whether grape seed proanthocyanidin extract (GSPE) which is known to act as an antioxidant has therapeutic effect on collagen-induced arthritis (CIA) in mice, an animal model of rheumatoid arthritis. Mice were treated with an intraperitoneal injection of GSPE (10, 50, or 100 mg/kg) or saline. Clinical, histo... | ['Acid Phosphatase', 'Animals', 'Ankle Joint', 'Antibodies', 'Arthritis, Experimental', 'Arthritis, Rheumatoid', 'Cells, Cultured', 'Collagen Type II', 'Disease Models, Animal', 'Grape Seed Extract', 'Hydrogen Peroxide', 'Interleukin-17', 'Isoenzymes', 'Isoprostanes', 'Macrophage Colony-Stimulating Factor', 'Mice', 'Mi... | 19,446,580 | [['D08.811.277.352.650.025'], ['B01.050'], ['A02.835.583.378.062'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['C05.550.114.015', 'E05.598.500.249'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['A11.251'], ['D05.750.078.280.300.200', 'D12.776.860.300.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative analyses of the kinetics and subunits of myosins from canine skeletal muscle and cardiac tissue. | Two types of canine cardiac myosins, myosin from the free wall of the right ventricle and the free wall of the left ventricle, were compared with canine skeletal muscle myosin from the gastrocnemius. The Vmax values for the ATPase reaction catalyzed by myosin were significantly different among the three types of tissue... | ['Adenosine Triphosphatases', 'Adenosine Triphosphate', 'Ammonium Chloride', 'Animals', 'Calcium', 'Dogs', 'Electrophoresis, Polyacrylamide Gel', 'Enzyme Activation', 'Heart Ventricles', 'Immunodiffusion', 'Kinetics', 'Muscles', 'Myocardium', 'Myosins', 'Organ Specificity', 'Potassium'] | 122,977 | [['D08.811.277.040.025'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D01.210.450.150.050', 'D01.625.062.249'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.196.401.402', 'E05.301.300.319'], ['G02.111.263', 'G... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recognition of a mycobacteria-specific epitope in the 65-kD heat-shock protein by synovial fluid-derived T cell clones. | Adjuvant arthritis in rats is induced by a T cell clone specific for amino acids 180-188 of the mycobacterial 65-kD heat-shock protein, and synovial T cell responses to this same Ag have been noted in human arthritis. We have isolated 65-kD Ag-specific T cell clones from synovial fluid mononuclear cells of a patient wi... | ['Antigens, Bacterial', 'Clone Cells', 'Epitopes', 'HLA-DR Antigens', 'Heat-Shock Proteins', 'Humans', 'Lymphocyte Activation', 'Male', 'Middle Aged', 'Mycobacterium', 'Synovial Fluid', 'T-Lymphocytes'] | 1,689,764 | [['D23.050.161'], ['A11.251.353'], ['D23.050.550'], ['D12.776.395.550.509.400.440', 'D12.776.543.550.440.400.440', 'D23.050.301.500.400.400.440', 'D23.050.301.500.450.400.440', 'D23.050.705.552.410.400.440', 'D23.050.705.552.450.400.440'], ['D12.776.580.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dendritic cells that endocytosed antigen-containing IgG-liposomes elicit effective antitumor immunity. | Liposomes represent a promising vehicle to deliver exogenous antigens to dendritic cells (DCs) for tumor immunotherapy. Targeting exogenous antigens to Fcgamma receptors on DCs has been shown to result in efficient presentation of antigen-derived peptides on major histocompatibility complex (MHC) class I and class II m... | ['Animals', 'Antigen Presentation', 'Antigens, Neoplasm', 'CD11c Antigen', 'Cancer Vaccines', 'Dendritic Cells', 'Endocytosis', 'Humans', 'Immunity, Cellular', 'Immunoglobulin G', 'Immunotherapy, Adoptive', 'Liposomes', 'Mice', 'Mice, Inbred C57BL', 'Monocytes', 'Neoplasms'] | 16,531,817 | [['B01.050'], ['G12.119', 'G12.450.050.400.070'], ['D23.050.285'], ['D12.776.395.550.200.074.875', 'D12.776.395.550.200.275.500', 'D12.776.543.550.200.093.875', 'D12.776.543.550.200.275.500', 'D12.776.543.750.705.408.100.200', 'D12.776.543.750.705.408.600.100.500', 'D12.776.543.750.705.833.249.500', 'D23.050.301.350.07... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Does PCA3 score and prostatic MRI help selection of patients scheduled for initial prostatic biopsy?]. | INTRODUCTION: Determinate if the adjunction of PCA3 score and/or prostatic MRI can improve the selection of the patients who have an indication of first prostate biopsy.PATIENTS AND METHODS: Multiparametric prostatic MRI and PCA3 score were made before biopsy to men scheduled for initial prostate biopsy for abnormal di... | ['Adult', 'Aged', 'Antigens, Neoplasm', 'Biomarkers, Tumor', 'Biopsy', 'Digital Rectal Examination', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neoplasm Grading', 'Patient Selection', 'Predictive Value of Tests', 'Prospective Studies', 'Prostate-Specific Antigen', 'Prostatectomy', 'Prostatic Neopla... | 23,352,305 | [['M01.060.116'], ['M01.060.116.100'], ['D23.050.285'], ['D23.101.140'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.370.600.600.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dissecting cell-type-specific roles of androgen receptor in prostate homeostasis and regeneration through lineage tracing. | Androgen signals through androgen receptor (AR) to influence prostate development and cancer. How stromal and epithelial AR regulate prostate homeostasis remains unclear. Using genetic lineage tracing, we systematically investigated the role of cell-autonomous AR in different prostate epithelial cell types. Here we sho... | ['Animals', 'Gene Expression Regulation', 'Genotype', 'Male', 'Mice', 'Mice, Transgenic', 'Orchiectomy', 'Organoids', 'Principal Component Analysis', 'Prostate', 'Receptors, Androgen', 'Selective Estrogen Receptor Modulators', 'Tamoxifen', 'Tissue Culture Techniques'] | 28,112,153 | [['B01.050'], ['G05.308'], ['G05.380'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['E04.270.282.679', 'E04.950.165.679', 'E04.950.774.860.618'], ['A10.802'], ['E05.318.740.562'], ['A05.360.444.575', 'A10.336.707'], ['D12.776.826.750.150'], ['D06... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Observer-based adaptive fuzzy synchronization for hyperchaotic systems. | In this paper, the synchronization problem of hyperchaotic systems is investigated. An adaptive fuzzy observer is proposed based on the Takagi-Sugeno fuzzy model. Theoretical analysis based on Lyapunov stability theory is provided to verify the feasibility of the proposed synchronization scheme. Numerical simulation of... | ['Algorithms', 'Computer Simulation', 'Fuzzy Logic', 'Models, Theoretical', 'Nonlinear Dynamics'] | 19,045,440 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['E05.599'], ['E05.599.850', 'H01.548.675']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Upregulation of Yy1 Suppresses Dilated Cardiomyopathy caused by Ttn insufficiency. | Truncating variants in TTN (TTNtv), coding for the largest structural protein in the sarcomere, contribute to the largest portion of familial and ambulatory dilated cardiomyopathy (DCM). TTN haploinsufficiency caused by TTNtv is suggested as the disease mechanism. However, it is unclear whether TTN insufficiency causes... | ['Cardiomyopathy, Dilated', 'Cell Cycle', 'HEK293 Cells', 'Humans', 'Myocytes, Cardiac', 'Protein Kinases', 'Up-Regulation', 'YY1 Transcription Factor'] | 31,705,051 | [['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['G04.144'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.541.704.570', 'A10.690.552.750.570', 'A11.620.500'], ['D08.811.913.696.620.682'], ['G02.111.905', 'G05.308.850', 'G07.690.773.998'], ['D12.776.260.235.8... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of postmortem serum and cerebrospinal fluid growth hormone levels in relation to the cause of death in forensic autopsy. | Previous studies have shown that postmortem serum levels of adrenocorticotropic hormone (ACTH) were significantly lower in cases of asphyxia and poisoning than in other groups, whereas ACTH levels in cerebrospinal fluid (CSF) were significantly lower for hypothermia and hyperthermia. This study comparatively analyzed g... | ['Adrenocorticotropic Hormone', 'Adult', 'Aged', 'Aged, 80 and over', 'Autopsy', 'Biomarkers', 'Carboxyhemoglobin', 'Cause of Death', 'Female', 'Forensic Pathology', 'Human Growth Hormone', 'Humans', 'Hypothalamo-Hypophyseal System', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Pituitary-Adrenal System', 'Young Adul... | 21,547,353 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['D23... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Using the theory of planned behavior to predict aggression and weapons carrying in urban African American early adolescent youth. | Aggressive and weapons carrying behaviors are indicative of youth violence. The theory of planned behavior is used in the current analysis to improve our understanding of violence-related behaviors. We examine the influence of perceived behavioral control (self-control and decision making) as a part of the overall fram... | ['Adolescent', 'Adolescent Behavior', 'African Americans', 'Age Factors', 'Aggression', 'Alcohol Drinking', 'Baltimore', 'Child', 'Female', 'Humans', 'Logistic Models', 'Male', 'Peer Group', 'Risk Factors', 'Self-Control', 'Sex Factors', 'Smoking', 'Socioeconomic Factors', 'Substance-Related Disorders', 'Violence', 'We... | 25,228,369 | [['M01.060.057'], ['F01.145.022'], ['M01.686.508.100.100', 'M01.686.754.100'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.145.126.125', 'F01.145.813.045'], ['F01.145.317.269'], ['Z01.107.567.875.500.500.100', 'Z01.433.100'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Substrate recognition by ribosome-inactivating protein studied by molecular modeling and molecular electrostatic potentials. | A computer model of dianthin 30, a type 1 ribosome-inactivating protein (RIP), is constructed by homology modeling using two known X-ray structures; a type 1 RIP, pokeweed antiviral protein (PAP), and chain A of a type 2 RIP, ricin. The 3D structure is refined by molecular dynamics and its binding site compared with th... | ['Amino Acid Sequence', 'Binding Sites', 'Chemical Phenomena', 'Chemistry, Physical', 'Computer Graphics', 'Computer Simulation', 'Crystallography, X-Ray', 'Electricity', 'Models, Molecular', 'Molecular Sequence Data', 'N-Glycosyl Hydrolases', 'Plant Proteins', 'Protein Binding', 'Protein Conformation', 'Ribosome Inact... | 7,619,790 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['G02'], ['H01.181.529'], ['L01.224.108', 'L01.296.110'], ['L01.224.160'], ['E05.196.309.742.225'], ['G01.358.500.249'], ['E05.599.595'], ['L01.453.245.667'], ['D08.811.277.450.430'], ['D12.776.765'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Non-vital, prosthetic, and virtual reality models of microsurgical training. | Many microsurgical training models exist. These can be broadly classified into living and non-living. The latter type can be further sub-classified into non-vital, prosthetic, and virtual reality models. We review each model within these sub-groups with reference to the ideal properties of a training model. The most im... | ['Clinical Competence', 'Humans', 'Microsurgery', 'Suture Techniques', 'User-Computer Interface'] | 11,757,067 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.494', 'E05.591.580'], ['E04.987.775'], ['L01.224.900.910']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
[A toddler with traumatic brain injury]. | A 14-month-old boy presented with a haematoma and an oedematous swelling in the left parieto-occipital region after sustaining a fall from 3 meters. CT images of the brain showed a multifragmentary fracture in the parietotemporal region. Because the swelling progressed during admission, an MRI of the brain was performe... | ['Accidental Falls', 'Brain Injuries', 'Glasgow Coma Scale', 'Humans', 'Infant', 'Male', 'Skull Fractures', 'Treatment Outcome'] | 23,446,151 | [['N06.850.135.122'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['E05.318.308.940.968.875.250', 'E05.944.500', 'N04.452.859.564.800.250', 'N05.715.360.300.715.500.800.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C10.900.300.918', 'C26.404.750', 'C26.915.300.745'], ['E01.78... | ['Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Quantifying the determinants of outbreak detection performance through simulation and machine learning. | OBJECTIVE: To develop a probabilistic model for discovering and quantifying determinants of outbreak detection and to use the model to predict detection performance for new outbreaks.MATERIALS AND METHODS: We used an existing software platform to simulate waterborne disease outbreaks of varying duration and magnitude. ... | ['Algorithms', 'Bayes Theorem', 'Computational Biology', 'Computer Simulation', 'Disease Outbreaks', 'False Positive Reactions', 'Humans', 'Machine Learning', 'Probability', 'ROC Curve', 'Sensitivity and Specificity'] | 25,445,482 | [['G17.035', 'L01.224.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['H01.158.273.180', 'L01.313.124'], ['L01.224.160'], ['N06.850.290'], ['E01.354.506'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17.035.250.500', 'L01.224.050.375.530'], ['E05.318.740.600', 'G17.680', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Quadruplex melting. | Melting curves are commonly used to determine the stability of folded nucleic acid structures and their interaction with ligands. This paper describes how the technique can be applied to study the properties of four-stranded nucleic acid structures that are formed by G-rich oligonucleotides. Changes in the absorbance (... | ['G-Quadruplexes', 'Guanine', 'Kinetics', 'Ligands', 'Temperature', 'Thermodynamics'] | 17,967,699 | [['G02.111.570.820.486.550', 'G05.360.580.550'], ['D03.633.100.759.758.399.454'], ['G01.374.661', 'G02.111.490'], ['D27.720.470.480'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['G01.906']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Simulation analysis of ASM/Tak?cs models in the BSM1 configuration. | The present paper summarizes the outlines of a simulation analysis study conducted on the BSM1 (formerly the COST benchmark) configuration using activated sludge models (ASM1, ASM2d and ASM3) coupled to Tak?cs settler model. The prime objective was to develop reliable simulation software programs to implement these com... | ['Ammonia', 'Bioreactors', 'Computer Simulation', 'Models, Biological', 'Nitrates', 'Nitrogen', 'Phosphorus', 'Sewage', 'Software', 'Waste Disposal, Fluid', 'Water'] | 17,144,265 | [['D01.362.075', 'D01.625.050'], ['E07.115', 'J01.897.120.115'], ['L01.224.160'], ['E05.599.395'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['D01.268.604', 'D01.362.625'], ['D01.268.666'], ['D20.944.932.500'], ['L01.224.900'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D01.045.250.8... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Prevalence and correlates of elevated blood pressure in youth with diabetes mellitus: the SEARCH for diabetes in youth study. | OBJECTIVE: To determine the prevalence and correlates of elevated blood pressure (BP) in youth with type 1 or type 2 diabetes mellitus by using data from the SEARCH Study.STUDY DESIGN: The analysis included youth aged 3 to 17 years with type 1 (n = 3691) and type 2 diabetes mellitus (n = 410) who attended a research vi... | ['Adolescent', 'Blood Pressure', 'Body Mass Index', 'Child', 'Child, Preschool', 'Diabetes Complications', 'Diabetes Mellitus, Type 1', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Hypertension', 'Male', 'Prevalence', 'United States'] | 20,394,942 | [['M01.060.057'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406'], ['M01.060.406.448'], ['C19.246.099'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Chitosan-Based Film of Tyrothricin for Enhanced Antimicrobial Activity against Common Skin Pathogens Including Staphylococcus aureus. | Chitosan-based film-forming gel is regarded as a promising vehicle for topical delivery of antimicrobial agents to skin wounds, since it protects from microbial infection and the cationic polymer itself possesses antibacterial activity. In this study, possible synergistic interaction against common skin pathogens betwe... | ['Anti-Bacterial Agents', 'Chitosan', 'Drug Combinations', 'Drug Synergism', 'Gels', 'Humans', 'Methicillin-Resistant Staphylococcus aureus', 'Microbial Sensitivity Tests', 'Microbial Viability', 'Pseudomonas aeruginosa', 'Skin', 'Staphylococcal Skin Infections', 'Staphylococcus aureus', 'Tyrothricin'] | 26,907,760 | [['D27.505.954.122.085'], ['D05.750.078.139.500', 'D09.698.211.500'], ['D26.310'], ['G07.690.773.968.477'], ['D20.280.320', 'D26.255.165.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.300.390.400.800.750.100.500', 'B03.353.500.750.750.100.500', 'B03.510.100.750.750.100.500', 'B03.510.400.790.750.100.500'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The human thermoregulation range within the neutral zone. | A mathematical and physical model of thermoregulatory mechanisms has been derived and experimental data are presented for the elements of the model. The thermoregulatory range within the neutral zone has been analyzed by regression analysis of the experimental data. The optimal globe temperature and the adaptational sh... | ['Body Temperature Regulation', 'Environmental Exposure', 'Humans', 'Models, Biological', 'Models, Theoretical', 'Regression Analysis', 'Temperature'] | 1,286,088 | [['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['E05.599'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Asbestos, asbestosis, and lung cancer: observations in Quebec chrysotile workers. | One prospective epidemiologic study of asbestos cement workers with radiological small opacities has been cited as a rationale for attributing excess lung cancer to asbestosis. This approach could have considerable practical value for disease attribution in an era of decreasing exposure. However, a recent International... | ['Aged', 'Asbestos, Serpentine', 'Asbestosis', 'Carcinogens', 'Humans', 'Inhalation Exposure', 'Lung', 'Lung Neoplasms', 'Male', 'Occupational Exposure', 'Prospective Studies', 'Quebec', 'Smoking'] | 9,400,709 | [['M01.060.116.100'], ['D01.524.500.050', 'D01.578.725.050.075', 'D01.578.725.500.050', 'D01.837.725.700.760.070.110', 'D01.837.725.700.760.535.400'], ['C08.381.483.581.125', 'C08.381.520.702.125', 'C24.800.127'], ['D27.888.569.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.112'], ['A04.411']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Chemical shift magnetic resonance imaging: applications in the abdomen and pelvis. | Chemical shift imaging allows unambiguous separation of lipid and water signals. Useful images include opposed-phase (water minus fat) and fat-suppressed images, which can be obtained with spin-echo or gradient-echo methods. Chemical shift techniques can be used to reduce artifacts, to expand dynamic range, to diagnose... | ['Adrenal Cortex Diseases', 'Adrenal Gland Neoplasms', 'Fatty Liver', 'Female', 'Humans', 'Liver', 'Liver Diseases', 'Magnetic Resonance Imaging'] | 1,605,955 | [['C19.053.098'], ['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['C06.552.241'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['C06.552'], ['E01.370.350.825.500']] | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A 3D tumor spheroid model for the T98G Glioblastoma cell line phenotypic characterization. | Major Glioblastoma's hallmarks include proliferation, invasion and heterogeneity. Biological 3D tumor spheroid models can serve as intermediate systems between traditional 2D cell culture and complex in vivo models. Tumor spheroids have been shown to more accurately reproduce the spatial organization and microenvironme... | ['Cell Line, Tumor', 'Glioblastoma', 'Humans', 'Models, Biological', 'Spheroids, Cellular'] | 31,383,287 | [['A11.251.210.190', 'A11.251.860.180'], ['C04.557.465.625.600.380.080.335', 'C04.557.470.670.380.080.335', 'C04.557.580.625.600.380.080.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['A11.251.800']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Benchmarking of Four Near Infrared Spectroscopy Devices for Long Time Use in Neonates. | BACKGROUND: Using near-infrared spectroscopy (NIRS) mixed tissue saturation can be calculated by measuring the oxygen saturation of oxygenated and deoxygenated erythrocytes in the tissue. Quality of the calculated value is not only dependent on the exposure of the measured values in the calculation, but also on externa... | ['Benchmarking', 'Brain', 'Humans', 'Infant', 'Infant, Newborn', 'Infant, Premature', 'Oximetry', 'Oxygen', 'Spectroscopy, Near-Infrared'] | 29,539,643 | [['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['E01.370.225.124.100.100.600', 'E01.370.370.380.600', 'E01.370.386.700.100.600', 'E05.200.12... | ['Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cost comparison of robotic-assisted laparoscopic hysterectomy versus standard laparoscopic hysterectomy. | The aim of the study was to assess if the cost of robotic-assisted total laparoscopic hysterectomy is similar to the cost of standard laparoscopic hysterectomy when performed by surgeons past their initial learning curve. A retrospective chart review of all hysterectomies was performed for benign indications without co... | ['Adult', 'Blood Loss, Surgical', 'Female', 'Hospitalization', 'Humans', 'Hysterectomy', 'Laparoscopy', 'Middle Aged', 'Operative Time', 'Organ Size', 'Postoperative Complications', 'Retrospective Studies', 'Robotic Surgical Procedures', 'Uterus'] | 26,530,837 | [['M01.060.116'], ['C23.550.414.300', 'C23.550.505.300'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['E04.614.374.500', 'N02.421.585.753.374.500'], ['E01.370.600.115.100.660', 'E05.041.124.71... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
[Complications, hospital mortality and survival following partial pancreaticoduodenectomy]. | OBJECTIVE: To analyse hospital mortality, complications and survival of patients after subtotal pancreaticoduodenectomy in the Academic Medical Centre, Amsterdam, the Netherlands, 1983-1996.DESIGN: Partly retrospective (1983-August 1987), partly prospective (September 1987-1996).METHOD: Patient characteristics, indicat... | ['Adult', 'Aged', 'Female', 'Hospital Mortality', 'Humans', 'Male', 'Middle Aged', 'Netherlands', 'Pancreatic Neoplasms', 'Pancreaticoduodenectomy', 'Postoperative Care', 'Prognosis', 'Prospective Studies', 'Reoperation', 'Retrospective Studies', 'Risk Factors', 'Survival Analysis'] | 9,545,715 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.542.651'], ['C04.588.274.761', 'C04.588.322.475', 'C06.301.761', 'C06.689.667', 'C19.344.42... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mitral valve surgery with surgical embolectomy for mitral valve endocarditis complicated by septic coronary embolism. | Acute myocardial infarction (AMI) complicated by septic coronary embolism due to active infective endocarditis is rare but usually fatal. We report a case of successful mitral valve surgery with surgical embolectomy in a 27-year-old man with an AMI complicated by septic coronary embolism due to mitral valve endocarditi... | ['Adult', 'Echocardiography', 'Embolectomy', 'Embolism', 'Endocarditis, Bacterial', 'Humans', 'Male', 'Mitral Valve', 'Myocardial Infarction', 'Treatment Outcome'] | 17,977,004 | [['M01.060.116'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E04.100.814.445'], ['C14.907.355.350'], ['C01.150.252.245', 'C01.190.249', 'C14.260.249', 'C14.280.282.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.541.510.507'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pulmonary blood flow patterns in patients with Fontan circulation. | BACKGROUND: After Fontan surgery there is no subpulmonary ventricle to modify pulmonary blood flow. The influence of the cardiac cycle on pulmonary blood flow patterns in various types of Fontan patients is unknown.METHODS: Blood flow patterns were investigated using phase-velocity cine magnetic resonance imaging in th... | ['Adolescent', 'Adult', 'Blood Flow Velocity', 'Case-Control Studies', 'Female', 'Follow-Up Studies', 'Fontan Procedure', 'Humans', 'Magnetic Resonance Imaging, Cine', 'Male', 'Pulmonary Artery', 'Pulmonary Circulation', 'Reference Values', 'Risk Assessment', 'Treatment Outcome', 'Tricuspid Atresia'] | 18,154,807 | [['M01.060.057'], ['M01.060.116'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.035.410.295', 'E04.100.376.410.295', 'E04.100.376.724.500', 'E04.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Tissue and body fluid distribution of antibacterial agents in pregnant and lactating women]. | OBJECTIVE: To determine the placental transfer and milk excretion of antibacterial agents.METHODS: A prospective study was conducted in pregnant and lactating women. The concentrations of 13 agents in tissue and body fluid were determined by bioassay or high performance liquid chromatography method.RESULTS: The results... | ['Anti-Bacterial Agents', 'Anti-Infective Agents', 'Breast Feeding', 'Female', 'Fetal Blood', 'Humans', 'Maternal-Fetal Exchange', 'Milk, Human', 'Postpartum Period', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Puerperal Disorders', 'Tissue Distribution'] | 9,596,854 | [['D27.505.954.122.085'], ['D27.505.954.122'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.455'], ['A12.200.467', 'A12.790.500', 'G07.203.100.700.500', 'G07... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Nivolumab-induced autoimmune diabetes mellitus presenting as diabetic ketoacidosis in a patient with metastatic lung cancer. | BACKGROUND: Advances in cancer immunotherapy have generated encouraging results in multiple malignancies refractory to standard chemotherapies. As the use of immune checkpoint inhibitors (ICI) proliferates, the incidence of autoimmune side effects associated with these agents, termed immune related adverse events (irAE... | ['Adenocarcinoma', 'Adult', 'Antibodies, Monoclonal', 'Antineoplastic Agents', 'Diabetes Mellitus, Type 1', 'Diabetic Ketoacidosis', 'Female', 'Humans', 'Lung Neoplasms', 'Nivolumab', 'Programmed Cell Death 1 Receptor'] | 28,515,940 | [['C04.557.470.200.025'], ['M01.060.116'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D27.505.954.248'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.076.176.652.500', 'C18.452.394.750.535', 'C19.246.099.812'], ['B01.050.150.900.649.313.988.400.1... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cotransplant of neural stem cells and NT-3 gene modified Schwann cells promote the recovery of transected spinal cord injury. | STUDY DESIGN: An animal model of transected spinal cord injury (SCI) was used to test the hypothesis that cografted neural stem cells (NSCs) and NT-3-SCs promote morphologic and functional recoveries of injured spinal cord.OBJECTIVE: To explore whether cotransplant of NSCs and NT-3-SCs could promote the injured spinal ... | ['Animals', 'Animals, Newborn', 'Cell Count', 'Cell Differentiation', 'Cells, Cultured', 'Disease Models, Animal', 'Evoked Potentials, Motor', 'Female', 'Immunohistochemistry', 'Nerve Regeneration', 'Nerve Tissue Proteins', 'Neural Conduction', 'Neurons', 'Neurotrophin 3', 'Rats', 'Rats, Sprague-Dawley', 'Reaction Time... | 16,773,039 | [['B01.050'], ['B01.050.050.282'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.152'], ['A11.251'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A low-cost, accurate method for detecting reticulocytes at different maturation stages based on changes in the mitochondrial membrane potential. | In the clinical setting, reticulocytes are used as an index for the hematopoietic function of the bone marrow. Different maturation stages of reticulocytes are early markers for bone marrow hematopoietic stem cell transplantation and bone marrow regeneration after chemotherapy. Therefore, we aimed to establish a method... | ['Animals', 'Blood Cells', 'Bone Marrow Cells', 'Cell Count', 'Erythrocyte Count', 'Erythropoiesis', 'Flow Cytometry', 'Membrane Potential, Mitochondrial', 'Mice', 'Reticulocytes', 'Staining and Labeling'] | 31,837,438 | [['B01.050'], ['A11.118', 'A15.145.229'], ['A11.148', 'A15.378.316'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['E01.370.225.500.195.107.330', 'E01.370.225.625.107.330', 'E05.200.500.195.107.330', 'E05.200.625.107.330', 'E05.242.195.107.330', 'G04.140.107.330', 'G09.188.105.330'], ['G04.152... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Renal uptake of fats and glycerol in endotoxin shock in dogs. | Circulatory changes and renal uptake of free fatty acids (FFA), glycerol and triglycerides were studied in ten adult beagle dogs during pentobarbital anesthesia. Six dogs were injected intravenously with E. coli endotoxin 0.5 mg/kg over 15 min and four control dogs received saline. Cardiac depression, hypotension, rena... | ['Animals', 'Blood Pressure', 'Cardiac Output', 'Dogs', 'Endotoxins', 'Escherichia coli', 'Fatty Acids, Nonesterified', 'Female', 'Glycerol', 'Kidney', 'Male', 'Renal Circulation', 'Shock, Septic', 'Triglycerides'] | 2,274,749 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.380.150', 'G09.330.380.124'], ['B01.050.150.900.649.313.750.250.216.200'], ['D23.946.123.329'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D10.251.310'], ['D02.033.800.875.500', 'D09.853.875.500'], ['A05.810.453'], ['G08.852.725', 'G... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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