Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Quantifying intersectionality: An important advancement for health inequality research. | BACKGROUND: Intersectionality is a powerful theoretical framework that is useful in describing the lived experiences of people with multiple marginalized statuses. By focusing on power and domination (e.g., racism, sexism), and the ways in which they are inextricably linked and mutually constructing, researchers can be... | ['Evaluation Studies as Topic', 'Health Status Disparities', 'Humans'] | 30,733,077 | [['E05.337', 'N05.715.360.335'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Stability of analytes related to clinical chemistry and bone metabolism in blood specimens after delayed processing. | OBJECTIVES: We investigated the stability of 36 analytes related to clinical chemistry in a controlled storage study.DESIGN AND METHODS: Blood was collected from 11 subjects and was maintained for 45 min, 2.5 h, 5 h, or 24 h after phlebotomy before centrifugation.RESULTS: Statistically significant changes were observed... | ['Bone and Bones', 'Centrifugation', 'Chemistry, Clinical', 'Humans', 'Osteocalcin', 'Parathyroid Hormone', 'Phlebotomy', 'Pyridoxal Phosphate', 'Specimen Handling', 'Time Factors'] | 19,250,930 | [['A02.835.232', 'A10.165.265'], ['E05.181'], ['H01.181.341'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.125.700'], ['D06.472.699.590', 'D12.644.548.587'], ['E01.370.225.998.110.625', 'E02.800.558', 'E04.665.150.625', 'E05.200.998.110.625'], ['D03.383.725.676.925.500.500', 'D08.211.740'], ['E01.370... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Recent surgical treatments for urinary stone disease in a Korean population: National population-based study. | OBJECTIVES: To provide surgical treatment trends for urinary stone disease in Korea.METHODS: We analyzed medical service claim data of surgical treatments to urinary stone disease submitted by medical service providers from the Health Insurance Review and Assessment Service from 2009 to 2016.RESULTS: There was a signif... | ['Cross-Sectional Studies', 'Female', 'Humans', 'Linear Models', 'Lithotripsy', 'Male', 'Nephrolithotomy, Percutaneous', 'Republic of Korea', 'Treatment Outcome', 'Ureteroscopy', 'Urolithiasis'] | 30,803,067 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['E02.600', 'E04... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The effects of antigen dose and adjuvant on the antibody response; amplification of restricted B cell clones. | Anti-DNP antibody production in inbred strain 2 guinea pigs immunized with chemically defined DNP-oligolysines was enhanced by increasing the antigen dose or employing more potent adjuvants. However, the increase in antibody titer was not accompanied by an increase in antibody heterogeneity. Only a small number of anti... | ['Adjuvants, Immunologic', 'Animals', 'Antibodies', 'Antibody Formation', 'Antigens', 'B-Lymphocytes', 'BCG Vaccine', 'Clone Cells', 'Cross Reactions', "Freund's Adjuvant", 'Guinea Pigs', 'Immunization', 'Isoelectric Focusing', 'Mycobacterium bovis', 'Nitrobenzenes', 'Polylysine', 'Time Factors'] | 774,983 | [['D27.505.696.477.067'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G12.450.050.370.250'], ['D23.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D20.215.894.135.825.100'], ['A11.251.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[A rare manifestation of sarcoidosis]. | This article reports the case of a 14-year-old boy who was presented in the case conference with symptoms of decreased visual acuity, scintillating scotomas and photophobia. Physical examination revealed right facial paralysis, parotid gland swelling, high fever and poor general condition. Ophthalmoscopy revealed anter... | ['Adolescent', 'Anti-Inflammatory Agents', 'Diagnosis, Differential', 'Humans', 'Male', 'Prednisolone', 'Sarcoidosis', 'Treatment Outcome', 'Uveoparotid Fever'] | 22,565,854 | [['M01.060.057'], ['D27.505.954.158'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.432.769.795'], ['C15.604.515.827'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['C15.604.515.827.865']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Surface antibacterial properties of resin and resin-modified dental cements. | OBJECTIVE: Cements possessing antibacterial properties may reduce bacteria-induced fixed partial denture complications. The purpose of this study was to evaluate the antibacterial properties of 4 dental cements using the direct contact test (DCT) and the agar diffusion test (ADT).METHOD AND MATERIALS: The ADT was perfo... | ['Analysis of Variance', 'Colony Count, Microbial', 'Compomers', 'Glass Ionomer Cements', 'Resin Cements', 'Statistics, Nonparametric', 'Streptococcus mutans'] | 17,216,909 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.225.875.220', 'E05.200.875.220'], ['D05.750.716.822.308.300', 'D25.339.291.150', 'D25.339.816.500.300', 'D25.720.716.822.308.300', 'J01.637.051.339.291.150', 'J01.637.051.339.816.500.300', 'J01.637.051.720.716.822.308.300'], ['D25.339.291.402... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Single-dose and multiple-dose pharmacokinetics and dose proportionality of intravenous and intramuscular HPâCD-diclofenac (Dyloject) compared with other diclofenac formulations. | STUDY OBJECTIVE: To evaluate single- and repeated-dose pharmacokinetics (PK) and dose proportionality of hydroxypropyl-â-cyclodextrin (HPâCD)-diclofenac compared with Voltarol after intravenous (IV) and intramuscular (IM) administration.DESIGN: Study 1: Single-dose randomized four-way crossover study. Study 2: Multiple... | ['2-Hydroxypropyl-beta-cyclodextrin', 'Administration, Oral', 'Adult', 'Anti-Inflammatory Agents, Non-Steroidal', 'Area Under Curve', 'Biological Availability', 'Cross-Over Studies', 'Diclofenac', 'Dose-Response Relationship, Drug', 'Excipients', 'Female', 'Humans', 'Infusions, Intravenous', 'Injections, Intramuscular'... | 23,744,759 | [['D04.345.103.333.500', 'D09.301.915.400.375.333.500', 'D09.698.365.855.400.375.333.500'], ['E02.319.267.100'], ['M01.060.116'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['G03.787.151', 'G07.690.725.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The value of treatment planning using CT and an immobilizing shell in radiotherapy for paranasal sinus carcinomas. | This article describes a method which uses CT scans and immobilizing shells radiation treatment planning (CT-assisted planning) for paranasal sinus carcinomas and the value of this method on the treatment outcome. Results of the treatment for 82 patients who had CT-assisted planning were compared with that of 88 patien... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Squamous Cell', 'Female', 'Humans', 'Immobilization', 'Male', 'Middle Aged', 'Paranasal Sinus Neoplasms', 'Prognosis', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy, Computer-Assisted', 'Tomography, X-Ray Computed'] | 2,912,946 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.472'], ['M01.060.116.630'], ['C04.588.443.665.650.693', 'C08.460.669.693', 'C08.460.692.503', 'C08.785.600.693', 'C09.603.669.693', 'C09.603.692.503', 'C... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
[Chondroma adjacent to Meckel's cave mimicking a fifth cranial nerve neurinoma. A case report]. | Cranial chondromas are tumours arising from chondrocyte embryonic remnants cells that usually appear in the skull base synchondrosis. In contrast to the rest of the organism, where chondroid tumours are the most common primary bone tumour just behind the haematopoietic lineage ones, they are a rarity at cranial level, ... | ['Adult', 'Chondroma', 'Cranial Nerve Neoplasms', 'Diagnosis, Differential', 'Humans', 'Male', 'Neurilemmoma', 'Skull Base', 'Skull Neoplasms', 'Trigeminal Nerve Diseases'] | 26,944,382 | [['M01.060.116'], ['C04.557.450.565.265'], ['C04.588.614.300', 'C04.588.614.596.240', 'C10.292.225', 'C10.551.360', 'C10.551.775.250'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.595', 'C04.557.580.600.610.595', 'C04.557.580.625.650.595'], ['A01.456.830', 'A02.835.232.781.750'],... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Precise diagnosis of infection in burn wound biopsy specimens. Combination of histologic technique, acridine orange staining, and culture. | This study developed a rapid manual histologic technique on burn wound biopsy specimens for an early diagnosis of infection. A total of 86 biopsy specimens were processed using this rapid manual method, acridine orange fluorescent staining for the detection of microorganisms, and a quantitative culture for the identifi... | ['Acridine Orange', 'Bacterial Infections', 'Biopsy', 'Burns', 'Histological Techniques', 'Humans', 'Staining and Labeling', 'Time Factors', 'Wound Infection'] | 2,473,075 | [['D03.633.300.046.250.150'], ['C01.150.252'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C26.200'], ['E01.370.225.750', 'E05.200.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670', 'E01... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effectiveness of India ink as a long-term colonic mucosal marker. | We prospectively studied the use of India ink as a long-term or "permanent" mucosal marker as part of a study investigating the natural history of diminutive distal colorectal polyps. Twenty-six patients had 32 India ink tatoos implanted. The tatoo sites of the 19 patients who were followed at least 6 months continued ... | ['Carbon', 'Colonic Polyps', 'Coloring Agents', 'Humans', 'Intestinal Mucosa', 'Intestinal Polyps', 'Prospective Studies', 'Rectal Neoplasms', 'Sigmoid Neoplasms', 'Staining and Labeling'] | 1,370,188 | [['D01.268.150'], ['C23.300.825.411.235'], ['D27.720.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.369', 'A10.615.550.444'], ['C23.300.825.411'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C04.588.274.476.411.307.790', 'C06.301.371.411.307.790', ... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Myelinization of the optic nerve in the albino mouse (the Agnes Bluhm Jena-Halle strain)]. | Knowledge of normal differentiations is indispensable for interpreting developmental disturbances in animal experiments. Accordingly, the investigations described in the present paper were aimed at explaining the process of myelinization of the optic nerve in the domestic mouse breed Agnes Bluhm Jena-Halle. First signs... | ['Animals', 'Astrocytes', 'Axons', 'Cell Differentiation', 'Mice', 'Mice, Inbred Strains', 'Microscopy, Electron', 'Myelin Sheath', 'Oligodendroglia', 'Optic Nerve'] | 6,645,270 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['G04.152'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ['E01.370.350.515.402', 'E05.595.402'], ['A08.637.600.500', 'A08.6... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pre-admission education in surgical rheumatology nursing: towards greater patient empowerment. | AIMS AND OBJECTIVES: This study compared the pre-admission education received by two groups of rheumatoid arthritis (RA) patients scheduled for hip arthroplasty. The specific aim was to compare these patients' knowledge about care-related issues and sense of certainty about that knowledge, empowering learning experienc... | ['Aged', 'Arthroplasty, Replacement, Hip', 'Chi-Square Distribution', 'Cohort Studies', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', "Nurse's Role", 'Osteoarthritis, Hip', 'Patient Education as Topic', 'Patient Satisfaction', 'Perioperative Nursing', 'Power, Psychological', 'Preop... | 21,040,004 | [['M01.060.116.100'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Promotion of activated human B cell apoptosis and inhibition of Ig production by soluble CD95 ligand: CD95-based downregulation of Ig production need not culminate in activated B cell death. | CD95/CD95L interactions are vital to normal lymphoid homeostasis and in the protection against autoimmunity. To directly assess the effects of CD95L on activated B cell survival and Ig responses, purified human peripheral blood B cells, activated in vitro with SAC + rIL2, were incubated with a soluble CD95L fusion prot... | ['ADP-ribosyl Cyclase', 'ADP-ribosyl Cyclase 1', 'Annexin A5', 'Antigens, CD', 'Antigens, CD20', 'Antigens, Differentiation', 'Apoptosis', 'B-Lymphocyte Subsets', 'B-Lymphocytes', 'Cell Separation', 'Cell Survival', 'Down-Regulation', 'Fas Ligand Protein', 'Gene Expression Regulation', 'Humans', 'Immunoglobulins', 'Lym... | 10,915,556 | [['D08.811.277.450.430.400.060', 'D08.811.913.400.725.115.660.060'], ['D08.811.277.450.430.400.060.500', 'D12.776.543.550.045'], ['D12.776.157.125.050.100'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.035.120', 'D23.050.301.264.051.120', 'D23.101.100.110.120', 'D23.101.100.150.120'], ['D23.050.301.26... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Detection and discrimination of Shigella sonnei and Shigella flexneri based on vacuolar responses in Saccharomyces cerevisiae. | This study provided a system for bacteria detection based on a lysosome-like-vacuole response in the yeast Saccharomyces cerevisiae. Vacuoles are factors known to activate the immune system in the presence of foreign substances. Here, Shigella sonnei and Shigella flexneri were exposed to yeast to analyze the alteration... | ['Amines', 'Bacterial Proteins', 'Bacterial Typing Techniques', 'Biomarkers', 'Colony Count, Microbial', 'Electrophoresis, Gel, Two-Dimensional', 'Fluorescent Dyes', 'Microscopy, Confocal', 'Saccharomyces cerevisiae', 'Shigella flexneri', 'Shigella sonnei', 'Vacuoles'] | 30,261,194 | [['D02.092'], ['D12.776.097'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['D23.101'], ['E01.370.225.875.220', 'E05.200.875.220'], ['E05.196.401.250', 'E05.301.300.230'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['E01.370.350.515.395', 'E05.595.395'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Access to care for patients with time-sensitive conditions in Pennsylvania. | STUDY OBJECTIVE: Collective knowledge and coordination of vital interventions for time-sensitive conditions (ST-segment elevation myocardial infarction [STEMI], stroke, cardiac arrest, and septic shock) could contribute to a comprehensive statewide emergency care system, but little is known about population access to t... | ['Adult', 'Child', 'Emergency Service, Hospital', 'Health Care Surveys', 'Health Services Accessibility', 'Heart Arrest', 'Humans', 'Myocardial Infarction', 'Patient Care Bundles', 'Pennsylvania', 'Shock, Septic', 'Stroke', 'Time Factors'] | 24,368,055 | [['M01.060.116'], ['M01.060.406'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N04.590.374.350', 'N05.300.430'], ['C14.280.383'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Clinical and echocardiographic study of mitral valve in children with severe rheumatic carditis. Aspects of prolapse or rupture]. | PURPOSE: To describe cases of rheumatic carditis with echocardiographic aspects of prolapse or rupture of mitral structures.METHODS: We described 16 cases of acute carditis (ages between 5-15 years). In 10 (group 1) there was aspect of mitral prolapse, in 6 (group 2) aspect of "flail". The measurements of anterior chor... | ['Acute Disease', 'Adolescent', 'Child', 'Child, Preschool', 'Chordae Tendineae', 'Female', 'Heart Rupture', 'Humans', 'Male', 'Mitral Valve', 'Mitral Valve Prolapse', 'Myocarditis', 'Prospective Studies', 'Rheumatic Heart Disease', 'Ultrasonography'] | 8,762,688 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['A07.541.510.240'], ['C14.280.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.541.510.507'], ['C14.280.484.400.500'], ['C14.280.238.625'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650']... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The dispersion of Echinococcus granulosus in the intestine of dogs. | We studied the dispersion of adult Echinococcus granulosus in the intestine of experimentally infected dogs at 2 scales of habitat use. On a coarse scale, worms were found most frequently in the anterior third of the small intestine. On a fine scale, clumps or aggregations, typically of 4-5 worms in an area of 12 mm2, ... | ['Animals', 'Dogs', 'Echinococcus', 'Feces', 'Female', 'Intestine, Small', 'Intestines', 'Male', 'Parasite Egg Count'] | 2,760,768 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.500.500.736.215.327'], ['A12.459'], ['A03.556.124.684'], ['A03.556.124'], ['E01.370.225.932.600', 'E05.200.932.600']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A rare cause of seizure masquerading as neoplasm. | The authors report the case of a young man with no significant medical history who presented with new-onset seizure and mass-like lesions isolated to the left cerebral hemisphere relating to malignancy. Biopsy revealed findings consistent with angiitis and investigations for secondary causes of angiitis was negative. T... | ['Adult', 'Biopsy', 'Brain Neoplasms', 'Cerebral Angiography', 'Cerebrum', 'Diagnosis, Differential', 'Epilepsy, Tonic-Clonic', 'Humans', 'Magnetic Resonance Angiography', 'Magnetic Resonance Imaging', 'Male', 'Neurologic Examination', 'Tomography, X-Ray Computed', 'Vasculitis, Central Nervous System'] | 22,798,309 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Neuroimaging diagnosis and therapeutic efficacy of different surgical methods of gliomatosis cerebri]. | OBJECTIVE: To explore the neuroimaging diagnosis and therapeutic efficacy of different surgical methods of gliomatosis cerebri.METHODS: 26 cases of gliomatosis cerebri at our department between September 2008 and September 2013 were retrospectively analyzed. Preoperative cranial computed tomography (CT), magnetic reson... | ['Biopsy', 'Brain Neoplasms', 'Glioma', 'Humans', 'Magnetic Resonance Imaging', 'Neuroimaging', 'Retrospective Studies', 'Tomography, X-Ray Computed'] | 25,152,287 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Interstitial cystitis patients' use and rating of complementary and alternative medicine therapies. | INTRODUCTION AND HYPOTHESIS: The purpose of this study was to describe the use of complementary and alternative medicine (CAM) therapies among interstitial cystitis (IC) patients, patients' perception of CAM therapies' effectiveness, and the association of time since diagnosis with perceived effectiveness of these ther... | ['Acupuncture', 'Complementary Therapies', 'Cystitis, Interstitial', 'Data Collection', 'Diet Therapy', 'Female', 'Humans', 'Perception', 'Physical Therapy Modalities', 'Treatment Outcome'] | 23,149,598 | [['H02.004'], ['E02.190'], ['C12.777.829.495.500', 'C13.351.968.829.495.500'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['E02.642.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593'], ['E02.779', 'E02.831.535'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.... | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[Role of sera from peptic ulcer patients in cell proliferation of human gastric carcinoma]. | This study aimed at the relationship of helicobacter pylori infection to gastric carcinoma pathogenesis. Forty-nine serum samples from patients with gastric and duodenal ulcer and 20 serum sample from normal subjects were collected for the assessment of serum gastrin by radioimmunoassay (RIA) and serum IgG, IgA and IgM... | ['Antibodies, Bacterial', 'Cell Division', 'Duodenal Ulcer', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Stomach Neoplasms', 'Stomach Ulcer', 'Tumor Cells, Cultured'] | 12,212,290 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['C01.150.252.400.466'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.900.649... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diazepam kinetics in relation to age and sex. | 27 male volunteers aged 20 to 91 years, and 13 female volunteers aged 21 to 33 years, received single 5 to 10 mg doses of diazepam intravenously. Diazepam pharmacokinetics were determined from concentrations measured in multiple plasma samples drawn during 7 days after each dose. Diazepam elimination half-life among ma... | ['Adult', 'Age Factors', 'Aged', 'Diazepam', 'Female', 'Humans', 'Kinetics', 'Male', 'Middle Aged', 'Sex Factors'] | 7,312,934 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['D03.633.100.079.080.070.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['M01.060.116.630'], ['N05.715.350.675', 'N06.850.490.875']] | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hemiarthroplasty versus total shoulder prosthesis: results of cemented glenoid components. | In this retrospective study, we compared the results of 705 total shoulder arthroplasties (TSAs) with 469 hemiarthroplasties (HSAs), all having been performed with the Aequalis shoulder prosthesis. Each group, both TSA and HSA, was comparable by age (mean, 63.9 years) and sex (853 men and 321 women). Each group had com... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement', 'Bone Cements', 'Female', 'Humans', 'Joint Diseases', 'Joint Prosthesis', 'Male', 'Middle Aged', 'Recovery of Function', 'Retrospective Studies', 'Rotator Cuff', 'Rotator Cuff Injuries', 'Rupture', 'Shoulder Joint', 'Treatm... | 16,517,357 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110', 'E04.650.110', 'E04.680.101.110'], ['D05.750.716.822.300', 'D25.720.716.822.300', 'D27.720.102.158', 'J01.637.051.720.716.822.300'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Differential diagnosis of intraspinal and extraspinal non-discogenic sciatica. | The aim of this study is to present a series of 11 patients with non-discogenic sciatica (NDS), and to review the diagnostic techniques of careful clinical and radiological examination. The cases include lumbar radicular herpes zoster, lumbar nerve root schwannoma, lumbar instability, facet hypertrophy, ankylosing spon... | ['Adult', 'Aged', 'Diagnosis, Differential', 'Female', 'Herpes Zoster', 'Humans', 'Low Back Pain', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neurilemmoma', 'Sciatica', 'Spinal Diseases', 'Tomography, X-Ray Computed'] | 18,789,864 | [['M01.060.116'], ['M01.060.116.100'], ['E01.171'], ['C01.925.256.466.930.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C04.557.465.625.650.595', 'C04.557.580.600.610.595', 'C04.557.580.625.650.595'], ['C10.668.829.500.675.800', 'C10... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Anti-influenza virus activity of the compound LY253963. | The compound LY253963 (1,3,4-thiadiazol-2-ylcyanamide) inhibited the in vitro replication of representative influenza A and B viruses in Madin-Darby canine kidney (MDCK) cells at concentrations of 1-3.2 micrograms/ml. The yield of an influenza A (H3N2) virus in primary rhesus monkey kidney (RMK) cells was inhibited at ... | ['Antiviral Agents', 'Cells, Cultured', 'Drug Resistance, Microbial', 'Drug Therapy, Combination', 'Influenza A virus', 'Influenza B virus', 'Microbial Sensitivity Tests', 'Mutation', 'Nitriles', 'Orthomyxoviridae', 'RNA, Messenger', 'Thiadiazoles', 'Viral Proteins'] | 2,080,866 | [['D27.505.954.122.388'], ['A11.251'], ['G06.225', 'G07.690.773.984.269'], ['E02.319.310'], ['B04.820.480.968.405.400'], ['B04.820.480.968.407.410'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G05.365.590'], ['D02.626'], ['B04.820.480.968'], ['D13.444.735.544'], ['D02.886.675.867', 'D03.383.129.70... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative study of effects of impact tone and steady state tone exposure: EP and concentration of K+ ion and Na+ ion. | To test the adequacy of equal energy principle (EEP), guinea pigs were exposed to impact tone. The changes in electrophysiological data, namely endocochlear potential (EP) and the change in K+ ion and Na+ ion concentrations in the endolymph were investigated. The frequency of impact tone was 1 pulse/second or 1 pulse/3... | ['Acoustic Stimulation', 'Animals', 'Cations, Monovalent', 'Cochlear Microphonic Potentials', 'Endolymph', 'Guinea Pigs', 'Mathematical Computing', 'Noise', 'Potassium', 'Sodium'] | 10,587,014 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['B01.050'], ['D01.248.497.300.459'], ['G07.265.216.500.370.223', 'G07.888.250.223', 'G11.561.200.500.370.223'], ['A12.207.270.517.324'], ['B01.050.150.900.649.313.992.550'], ['L01.224.680'], ['G01.750.770.776.567', 'G16.500.275.600', 'N06.230.400', 'N06.850.460.610'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Development of sarcoidosis 6-month post discontinuation of etanercept: coincidence or real association? | There have been numerous reports of granulomatous diseases developing in patients receiving anti-tumour necrosis factor (TNF) therapy. Herein, we report a patient who developed sarcoidosis 6 months after discontinuation of etanercept. To date, all reported cases have occurred in patients undergoing ongoing treatment wi... | ['Abatacept', 'Anti-Inflammatory Agents, Non-Steroidal', 'Antibodies, Monoclonal, Murine-Derived', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Drug Therapy, Combination', 'Etanercept', 'Humans', 'Immunoconjugates', 'Immunoglobulin G', 'Immunosuppressive Agents', 'Male', 'Methotrexate', 'Middle Aged', 'Radiography... | 21,380,931 | [['D12.776.124.790.651.114.580.225', 'D12.776.377.715.548.114.580.225'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', '... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Effect of lncRNA HOTAIR on the radiosensitivity of HCCLM3 cells]. | Objective: To investigate the effect of down-regulating long non-coding RNA (lncRNA) and HOX transcript antisense RNA (HOTAIR) targeting miR-761 on the radiosensitivity of HCCLM3. Methods: The expression of HOTAIR in liver cancer cells HuH-7, SNU-449, HCCLM3 and normal liver cells L-02 were measured by real-time quanti... | ['Apoptosis', 'Cell Line, Tumor', 'Cell Proliferation', 'Gene Expression Regulation, Neoplastic', 'Humans', 'MicroRNAs', 'RNA, Long Noncoding', 'Radiation Tolerance'] | 32,392,994 | [['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['D13.444.735.790.375'], ['G04.712', 'G07.738']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Induction of drug-metabolizing enzymes by phenobarbitone: structural and biochemical aspects. | Two aspects of the induction of microsomal monooxygenases by phenobarbitone have been investigated. First, structural associations between mitochondria and single cisternae of rough endoplasmic reticulum (mitochondria--RER complexes) may operate as functional units in the biosynthesis of cytochrome P-450. This was dedu... | ['Aminolevulinic Acid', 'Animals', 'Cells, Cultured', 'Chick Embryo', 'Cytochrome P-450 Enzyme System', 'Endoplasmic Reticulum', 'Heme', 'Hemeproteins', 'Liver', 'Male', 'Microsomes, Liver', 'Mitochondria', 'Mixed Function Oxygenases', 'Phenobarbital', 'Rats'] | 6,906,260 | [['D02.241.755.547.276', 'D12.125.262'], ['B01.050'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['A11.284.430.214.190.875.248'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrochemical preparation of Nb2 | The present work describes the synthesis of niobium oxide nanochannels (Nb2O5NCs) with high surface area, porosity, photocurrent density, and photoelectrochemical stability as photocatalyst. The Nb2O5NCs were prepared by electrochemical anodization of niobium foil in different electrolytes: 1 M H2SO4 containing 0.4 wt%... | ['Coloring Agents', 'Niobium', 'Organic Chemicals', 'Oxides', 'Photolysis', 'Titanium', 'Water Purification'] | 32,480,087 | [['D27.720.233'], ['D01.268.556.615', 'D01.268.956.687', 'D01.552.544.615'], ['D02'], ['D01.248.497.158.685', 'D01.650.550'], ['G02.740.685'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Salt dependence of the formation and stability of the signaling state in G protein-coupled receptors: evidence for the involvement of the Hofmeister effect. | We studied the salt dependence of both the stability and the equilibrium of the late photoproducts metarhodopsin I (MI) and II (MII) of the artificial visual pigment 9-demethyl rhodopsin (9dm-Rho). In the photoproducts of 9dm-Rho, all-trans-9-demethyl retinal acts only as a partial agonist, enabling us to study the pho... | ['Animals', 'Cattle', 'Cell Membrane', 'Detergents', 'GTP-Binding Proteins', 'Hydrogen-Ion Concentration', 'Micelles', 'Osmolar Concentration', 'Photochemistry', 'Protein Conformation', 'Retinaldehyde', 'Rhodopsin', 'Rod Cell Outer Segment', 'Salts', 'Schiff Bases', 'Signal Transduction', 'Sodium Chloride', 'Solvents',... | 11,148,043 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.284.149'], ['D27.720.877.265', 'J01.516.381'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['G02.300'], ['D05.374', 'D26.255.560'], ['G02.640'], ['H01.181.529.711'], ['G02.111.570.820.709'], ['D02.047.850', 'D02.455.326.271.665.202.495.690', 'D02.455.426.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Quantitative structure-activity analyses of nitrobenzene toxicity to Tetrahymena pyriformis. | Toxicity data for the 50% growth inhibitory concentration against Tetrahymena pyriformis (log (IGC50-1)) for 42 alkyl- and halogen-substituted nitro- and dinitrobenzenes were obtained experimentally. Log (IGC50-1) along with the hydrophobicity, the logarithm of the 1-octanol/water partition coefficient (log Kow), and t... | ['Animals', 'Environmental Pollutants', 'Models, Chemical', 'Nitrobenzenes', 'Structure-Activity Relationship', 'Tetrahymena pyriformis'] | 9,705,752 | [['B01.050'], ['D27.888.284'], ['E05.599.495'], ['D02.455.426.559.389.565', 'D02.640.529'], ['G02.111.830', 'G07.690.773.997'], ['B01.043.185.650.375.750.850.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Strand-selective transcription of globin genes in rabbit erythroid cells and chromatin. | In order to investigate the symmetry of globin gene transcription, complementary RNA (cRNA) was synthesized using rabbit globin complementary DNA (cDNA) as a template for Escherichia coli DNA-dependent RNA polymerase (RNA nucleotidyltransferase). The cRNA hybridized specifically to its own cDNA template but not to shee... | ['Animals', 'Bone Marrow', 'Bone Marrow Cells', 'Chromatin', 'DNA-Directed RNA Polymerases', 'Escherichia coli', 'Genes', 'Globins', 'Kinetics', 'Nucleic Acid Hybridization', 'Protein Biosynthesis', 'Rabbits', 'Templates, Genetic', 'Transcription, Genetic'] | 1,108,006 | [['B01.050'], ['A15.382.216'], ['A11.148', 'A15.378.316'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D08.811.913.696.445.735.270'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340'], ['D12.776.422.316'], ['G01.374.661', 'G02.111.490'], ['E05.393.661',... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Disruption of adeB gene has a greater effect on resistance to meropenems than adeA gene in Acinetobacter spp. isolated from University Malaya Medical Centre. | INTRODUCTION: The AdeABC pump of Acinetobacter spp. confers resistance to various antibiotic classes. This pump is composed of the AdeA, AdeB, and AdeC proteins where AdeB is a member of the resistance-nodulation-division efflux pump superfamily. The adeA, adeB, and adeC genes are contiguous and adjacent to adeS and ad... | ['Acinetobacter', 'Acinetobacter Infections', 'Anti-Bacterial Agents', 'Bacterial Proteins', 'Carbapenems', 'Drug Resistance, Multiple, Bacterial', 'Humans', 'Malaysia', 'Membrane Transport Proteins', 'Meropenem', 'Models, Genetic', 'Mutation', 'Plasmids', 'Polymerase Chain Reaction', 'Sequence Analysis, DNA', 'Thienam... | 19,710,984 | [['B03.440.400.425.537.050', 'B03.660.250.530.050'], ['C01.150.252.400.560.022'], ['D27.505.954.122.085'], ['D12.776.097'], ['D02.065.589.099.124', 'D03.633.100.300.124'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Design considerations for an eHealth decision support tool in inflammatory bowel disease self-management. | BACKGROUND: Electronic health (eHealth) decision support tools have the potential to: facilitate inflammatory bowel disease (IBD) self-management, reduce health care utilisation and alleviate the pressure on overburdened outpatient clinics. The purpose of this study was to explore the perspectives of key stakeholders o... | ['Australia', 'Decision Support Techniques', 'Female', 'Focus Groups', 'Humans', 'Inflammatory Bowel Diseases', 'Male', 'Patient Participation', 'Qualitative Research', 'Self-Management', 'Telemedicine'] | 29,136,332 | [['Z01.639.100', 'Z01.678.100.373'], ['E05.245', 'L01.313.500.750.190'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.205.731', 'C06.405.469.432'], ['F01.100.150.750.500.620', 'F01.145.488.887.500.620', 'N02.421.143.212.300', 'N03.540.245.... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Simple model to explain effects of plasma protein binding and tissue binding on calculated volumes of distribution, apparent elimination rate constants and clearances. | A simple pharmacokinetic model, incorporating linear plasma protein binding, linear tissue binding, and first order elimination of free (unbound) drug, was studied. If Clp is the plasma clearance, Vf is the "true" volume of distribution of free drug, beta is the apparent elimination rate constant, sigma is the fraction... | ['Blood Proteins', 'Kinetics', 'Mathematics', 'Metabolic Clearance Rate', 'Models, Biological', 'Pharmaceutical Preparations', 'Protein Binding', 'Proteins'] | 1,001,358 | [['D12.776.124'], ['G01.374.661', 'G02.111.490'], ['H01.548'], ['E01.370.225.843', 'E05.200.843', 'G03.490', 'G07.690.595', 'G07.690.725.513'], ['E05.599.395'], ['D26'], ['G02.111.679', 'G03.808'], ['D12.776']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Digital analysis of mouthrinses' staining characteristics on provisional acrylic resins. | Provisional restorations are expected to be both aestethically and physically durable during the preparation of permanent restorations. In this study, the staining properties of mouthrinses containing chlorhexidine gluconate, benzydamine hydrochloride and a hybrid mouthrinse were investigated on light and dark shades o... | ['Acrylic Resins', 'Benzydamine', 'Chlorhexidine', 'Color', 'Colorimetry', 'Coloring Agents', 'Dental Restoration, Temporary', 'Drug Combinations', 'Humans', 'Mouthwashes', 'Photography'] | 17,371,568 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['D03.383.129.539.487.130', 'D03.633.100.449.130'], ['D02.078.370.141.100'], ['G01.590.540.199'], ['E05.196.922.250'], ['D27.720.233'], ['E06.323.528', 'E06.780.346.740', 'E07.695.190.192'], ['D26.310'], ['B01.050.150.900.649.313.988.400.11... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Inhibition of matrix metalloproteinases reduces local and distant organ injury following experimental acute pancreatitis. | BACKGROUND: Pulmonary complications from pancreatitis involve parenchymal destruction via proteolytic enzymes. Matrix metalloproteinases (MMPs) may play an important role in pulmonary injury following acute severe pancreatitis. We hypothesized that local and distant organ injury would be decreased by the presence of an... | ['Amylases', 'Animals', 'Lung', 'Lung Diseases', 'Male', 'Matrix Metalloproteinase Inhibitors', 'Matrix Metalloproteinases', 'Metalloendopeptidases', 'Models, Animal', 'Pancreas', 'Pancreatic Diseases', 'Pancreatitis, Acute Necrotizing', 'Peroxidase', 'Phenylalanine', 'Protease Inhibitors', 'Rats', 'Rats, Sprague-Dawle... | 12,643,851 | [['D08.811.277.450.066'], ['B01.050'], ['A04.411'], ['C08.381'], ['D27.505.519.389.745.610'], ['D08.811.277.656.300.480.525', 'D08.811.277.656.675.374.525'], ['D08.811.277.656.300.480', 'D08.811.277.656.675.374'], ['E05.598'], ['A03.734'], ['C06.689'], ['C06.689.750.650'], ['D08.811.682.732.700'], ['D12.125.072.050.685... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Physiological response to "pressure-demand" respirator wear. | This investigation determined cardiorespiratory responses of subjects with normal lung function and exercise tolerance and compared them with subjects with moderate impairment of lung function and exercise tolerance. The respirator was an air-line full-face mask (MSA-Ultravue) "pressure-demand" breathing type equipped ... | ['Adult', 'Female', 'Heart Rate', 'Humans', 'Male', 'Oxygen Consumption', 'Physical Exertion', 'Pressure', 'Protective Devices', 'Respiratory Function Tests', 'Respiratory Protective Devices', 'Stress, Physiological'] | 7,148,683 | [['M01.060.116'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.680'], ['G11.427.683'], ['G01.374.715'], ['E07.700', 'J01.637.708'], ['E01.370.386.700'], ['E07.700.700', 'J01.637.708.560.937'], ['G07.775']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Hypoalgesia in response to transcutaneous electrical nerve stimulation (TENS) depends on stimulation intensity. | UNLABELLED: Transcutaneous electrical nerve stimulation (TENS) is an electrophysical modality used for pain management. This study investigated the dose response of different TENS intensities on experimentally induced pressure pain. One hundred and thirty TENS na?ve healthy individuals (18-64 years old; 65 males, 65 fe... | ['Adolescent', 'Adult', 'Analysis of Variance', 'Biophysical Phenomena', 'Biophysics', 'Double-Blind Method', 'Female', 'Hand', 'Humans', 'Hyperalgesia', 'Male', 'Middle Aged', 'Pain', 'Pain Management', 'Pain Measurement', 'Pain Threshold', 'Transcutaneous Electric Nerve Stimulation', 'Young Adult'] | 21,481,649 | [['M01.060.057'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G01.154'], ['H01.158.344', 'H01.671.100'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.751.791... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of different structural foot types for measures of standing postural control. | STUDY DESIGN: Matched group comparison of 3 subject groups with 3 different foot structures for force plate and clinical measures of postural control.OBJECTIVES: To determine if subjects with different weight-bearing foot structure would demonstrate differences in static standing postural control, and to determine the ... | ['Adolescent', 'Adult', 'Female', 'Foot', 'Humans', 'Male', 'Pronation', 'Proprioception', 'Reproducibility of Results', 'Supination', 'Weight-Bearing'] | 17,193,872 | [['M01.060.057'], ['M01.060.116'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.410.698.840'], ['F02.830.816.541', 'G07.888.750', 'G11.561.790.541'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['G11.427.410.698.920'], ['G01.374.965']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A controlled study of psychological and social change after surgical gender reassignment in selected male transsexuals. | Of two groups of 20 patients accepted for gender reassignment surgery, one was offered early operation and therefore had had surgery by follow-up two years later, while the second was still awaiting operation at two-year follow-up. Although the groups were similar initially, significant differences between them emerged... | ['Adaptation, Psychological', 'Adult', 'Follow-Up Studies', 'Gender Identity', 'Genitalia, Male', 'Humans', 'Male', 'Middle Aged', 'Personality Tests', 'Postoperative Complications', 'Prospective Studies', 'Social Environment', 'Transsexualism'] | 2,224,377 | [['F01.058'], ['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['A05.360.444'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711.647'], ['C2... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Enhancement of image quality with a fast iterative scatter and beam hardening correction method for kV CBCT. | The problem of the enormous amount of scattered radiation in kV CBCT (kilo voltage cone beam computer tomography) is addressed. Scatter causes undesirable streak- and cup-artifacts and results in a quantitative inaccuracy of reconstructed CT numbers, so that an accurate dose calculation might be impossible. Image contr... | ['Algorithms', 'Calibration', 'Equipment Design', 'Head', 'Humans', 'Imaging, Three-Dimensional', 'Monte Carlo Method', 'Pelvis', 'Phantoms, Imaging', 'Photography', 'Radiation Dosage', 'Radiographic Image Enhancement', 'Radiography, Thoracic', 'Radiotherapy', 'Scattering, Radiation'] | 19,761,093 | [['G17.035', 'L01.224.050'], ['E05.978.155'], ['E05.320'], ['A01.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['A01.923.600'], ['E07.671'], ['E01.370.350.600', 'E05.712'], ['E05.799.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Training radial basis function networks for wind speed prediction using PSO enhanced differential search optimizer. | This paper presents an integrated hybrid optimization algorithm for training the radial basis function neural network (RBF NN). Training of neural networks is still a challenging exercise in machine learning domain. Traditional training algorithms in general suffer and trap in local optima and lead to premature converg... | ['Machine Learning', 'Models, Theoretical', 'Neural Networks, Computer', 'Wind'] | 29,768,463 | [['G17.035.250.500', 'L01.224.050.375.530'], ['E05.599'], ['G17.485', 'L01.224.050.375.605'], ['G16.500.175.249.200', 'G16.500.275.063.725.154.200', 'G16.500.750.775.780', 'N06.230.132.644.875', 'N06.230.300.100.150.185.200', 'N06.230.300.100.725.780']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Genomic organization of low copy number sequences that are associated with deca-satellite DNA in the monkey genome. | A previously described segment of African green monkey DNA (cloned in phage lambda MkA) contains deca-satellite linked to DNA sequences that are estimated to occur once per genome. Sequences homologous to the low copy number sequences in lambda MkA are also associated with species-specific satellite DNAs in the human a... | ['Animals', 'Cercopithecus', 'Chlorocebus aethiops', 'DNA Restriction Enzymes', 'DNA, Recombinant', 'DNA, Satellite', 'Humans', 'Mice', 'Sequence Homology, Nucleic Acid', 'Species Specificity'] | 2,825,119 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.199.120.126'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D13.444.308.460'], ['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.360.340.0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Magnetic resonance imaging-based spirometry for regional assessment of pulmonary function. | In this work MRI-based spirometry is presented as a method for noninvasively assessing pulmonary mechanical function on a regional basis. A SPAMM tagging sequence was modified to allow continuous dynamic imaging of the lungs during respiration. A motion-tracking algorithm was developed to track material regions from ti... | ['Adult', 'Algorithms', 'Artificial Intelligence', 'Female', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Lung', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Pattern Recognition, Automated', 'Pulmonary Ventilation', 'Reproducibility of Results', 'Resp... | 16,217,776 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.400', 'L01.224.308.410'], ['A04.411'], ['E01.370.350.825.500'], ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Uncapped nanobranch-based CuS clews used as an efficient peroxidase mimic enable the visual detection of hydrogen peroxide and glucose with fast response. | Nanosized materials acting as substitutes of natural enzymes are currently attracting significant research due to their stable enzyme-like characteristics, but some flaws of these nanozymes, including their limited catalytic rate and efficiency, need to be remedied to enable their wider applications. In this work, we v... | ['Biomimetic Materials', 'Biosensing Techniques', 'Copper', 'Glucose', 'Glucose Oxidase', 'Hydrogen Peroxide', 'Nanostructures', 'Peroxidase', 'Time Factors'] | 27,846,988 | [['J01.637.087'], ['E05.601.043'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D09.947.875.359.448'], ['D08.811.682.047.239'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['J01.637.512'], ['D08.811.682.732.700'], ['G01.910.857']] | ['Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Immunotherapy with imiquimod 5% cream for eyelid nodular basal cell carcinoma. | PURPOSE: To evaluate the efficacy and safety of topical imiquimod 5% cream for the treatment of eyelid basal cell carcinoma.DESIGN: Two interventional case reports.METHODS: Imiquimod 5% cream was applied topically once daily, 3 days a week for 8 to 12 weeks, in two patients affected by eyelid nodular basal cell carcino... | ['Administration, Topical', 'Aged, 80 and over', 'Aminoquinolines', 'Antineoplastic Agents', 'Carcinoma, Basal Cell', 'Eyelid Neoplasms', 'Female', 'Humans', 'Imiquimod', 'Immunotherapy', 'Interferon Inducers', 'Male', 'Ointments', 'Treatment Outcome'] | 16,376,667 | [['E02.319.267.120'], ['M01.060.116.100.080'], ['D03.633.100.810.050'], ['D27.505.954.248'], ['C04.557.470.200.165', 'C04.557.470.565.165'], ['C04.588.443.392.500', 'C11.319.421', 'C11.338.526'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.810.050.545'], ['E02.095.465.425'], ['D27.505.696.477.828'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Diagnostic laparoscopy in gunshot wounds of the abdomen in children]. | Diagnostic laparoscopy in gunshot wounds of the abdomen was performed in 14 children. The diagnostic value of laparoscopic and other methods of diagnostics was evaluated. An analysis of the results has shown that laparoscopy for gunshot wounds of the abdomen in children is of great diagnostic value. The indications and... | ['Abdomen', 'Child', 'Female', 'Humans', 'Laparoscopy', 'Male', 'Wounds, Gunshot'] | 16,881,172 | [['A01.923.047'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['C26.986.900']] | ['Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Implementation of UV-based advanced oxidation processes in algal medium recycling. | Algae show great potential as sustainable feedstock for numerous bioproducts. However, large volume of water consumption during algal biomass production makes that the culture media recycling is a necessity due to economic and environmental concern. To avoid the negative effect of enriched organic matters in the harves... | ['Hydrogen Peroxide', 'Microalgae', 'Oxidation-Reduction', 'Recycling', 'Ultraviolet Rays', 'Waste Disposal, Fluid', 'Waste Water', 'Water Pollutants, Chemical'] | 29,627,547 | [['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['B05.080.500.600.500'], ['G02.700', 'G03.295.531'], ['N06.850.780.200.800.800.525', 'N06.850.860.510.244'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891', 'G01.750.750.659', 'G01.750.770.578.891', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Virus neutralising activity of African fruit bat (Eidolon helvum) sera against emerging lyssaviruses. | It is likely that phylogroup 2 lyssaviruses circulate within bat reservoirs. We adapted a pseudotype (pt) neutralisation assay (PNA) to a multiplex format enabling serosurveillance for Lagos bat virus (LBV), Mokola virus (MOKV) and West Caucasian bat virus (WCBV) in a potential reservoir, the African straw-coloured fru... | ['Animals', 'Antibodies, Viral', 'Biological Evolution', 'Chiroptera', 'Communicable Diseases, Emerging', 'Disease Reservoirs', 'Female', 'Ghana', 'HEK293 Cells', 'Humans', 'Lyssavirus', 'Male', 'Neutralization Tests', 'Rabies virus', 'Rhabdoviridae Infections', 'Species Specificity'] | 20,951,400 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['G05.045', 'G16.075'], ['B01.050.150.900.649.313.937'], ['C01.221.500', 'C23.550.291.531.750'], ['N06.850.520.203.250'], ['Z01.058.290.190.320'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.31... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Design, synthesis, and evaluation of genipin derivatives for the treatment of Alzheimer's Disease. | Twenty-two novel genipin derivatives have been designed, synthesized, and evaluated for their inhibitory activity against acetylcholinesterase (AChE). As a result, compound 13a bearing ligustrazine moiety displayed the most potent AChE inhibitory activity in this series with IC50 value of 218 nm. Besides, MTT assay was... | ['Acetylcholinesterase', 'Alzheimer Disease', 'Amyloid beta-Peptides', 'Animals', 'Binding Sites', 'Cell Survival', 'Drug Design', 'Inhibitory Concentration 50', 'Iridoids', 'Molecular Docking Simulation', 'Neuroprotective Agents', 'PC12 Cells', 'Peptide Fragments', 'Protein Structure, Tertiary', 'Rats', 'Structure-Act... | 29,543,387 | [['D08.811.277.352.100.170.176'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['G02.111.570.120'], ['G04.346'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['E05.940.350', 'G07.690.936.563'], ['D02.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Atlas registration for edema-corrected MRI lesion volume in mouse stroke models. | Lesion volume measurements with magnetic resonance imaging are widely used to assess outcome in rodent models of stroke. In this study, we improved a mathematical framework to correct lesion size for edema which is based on manual delineation of the lesion and hemispheres. Furthermore, a novel MATLAB toolbox to registe... | ['Animals', 'Blood-Brain Barrier', 'Brain Edema', 'Disease Models, Animal', 'Magnetic Resonance Imaging', 'Male', 'Mice', 'Stroke'] | 28,829,217 | [['B01.050'], ['A07.035', 'A08.186.211.035'], ['C10.228.140.187'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.350.825.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['C10.228.140.300.775', 'C14.907.253.855']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Induction of tolerance in quadruple chimeric mice. | Human cord blood (CB) contains hematopoietic stem cells and progenitors. Because the major limitation to a widespread use of CB for transplantation lies in its limited volume, it is necessary to combine the CB from several donors. In this study, we show that lethally irradiated mice can be reconstituted with the inject... | ['Animals', 'Bone Marrow Transplantation', 'Cell Lineage', 'Cell Proliferation', 'Cord Blood Stem Cell Transplantation', 'Female', 'Graft Survival', 'Histocompatibility Antigens', 'Humans', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C3H', 'Mice, Inbred C57BL', 'Mice, Inbred DBA', 'Phenotype', 'Skin', 'Skin Tr... | 15,342,933 | [['B01.050'], ['E02.095.147.725.040', 'E04.936.580.040'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['G04.161.750', 'G07.345.249.410.750'], ['E02.095.147.500.500.312', 'E04.936.225.687.312'], ['G12.875.545.340'], ['D23.050.301.500', 'D23.050.705.552'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The impact of the Thai motorcycle transition on road traffic injury: Thai Cohort Study results. | OBJECTIVES: The aim of this study was to investigate the impact of motorcycle to car transitioning and urbanisation on traffic injury rates in Thailand.DESIGN: Analysis of two consecutive surveys of a large national cohort study.SETTING: Thailand.PARTICIPANTS: The data derived from 57,154 Thai Cohort Study (TCS) partic... | ['Accidents, Traffic', 'Adult', 'Cohort Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Motorcycles', 'Thailand'] | 25,826,214 | [['N06.850.135.392'], ['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['J01.937.500.500'], ['Z01.252.145.841']] | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
A transcriptional silencer controls the developmental expression of the CD4 gene. | The appropriate expression of the CD4 glycoprotein is required for T-cell function and development. Here we define the transcriptional control elements in the CD4 locus that convey CD(4+)-specific expression of a marker gene in transgenic mice. Using nuclear run-on experiments, we have determined that the major mechani... | ['Animals', 'CD4 Antigens', 'CD8 Antigens', 'Cells, Cultured', 'Enhancer Elements, Genetic', 'Gene Expression Regulation', 'Genetic Markers', 'HLA-B7 Antigen', 'Humans', 'Mice', 'Mice, Transgenic', 'Models, Genetic', 'Promoter Regions, Genetic', 'Regulatory Sequences, Nucleic Acid', 'Spleen', 'T-Lymphocyte Subsets', 'T... | 8,062,832 | [['B01.050'], ['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.894.100', 'D23.101.100.894.100'], ['D23.050.301.264.894.108', 'D23.101.100.894.108'], ['A11.251'], ['G02.111.570.080.689.330', 'G05.360.080.689.330', 'G05.360.340.024.340.137.750.249'], ['G05.308'], ['D23.101.387', 'G0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structure and expression of three src2 homologues and a novel subfamily of flavoprotein monooxygenase genes revealed by the analysis of a 25kb fragment from Arabidopsis thaliana chromosome IV. | Biological and computer-assisted analyses of a 25kb fragment from Arabidopsis thaliana chromosome IV led to the characterization of two multigene families and three novel orphan genes, not previously described. The first gene family named AtMO1-4 encodes monooxygenases, related to the prokaryotic salicylate hydroxylase... | ['Amino Acid Sequence', 'Arabidopsis', 'Chromosome Mapping', 'Cloning, Molecular', 'Flavoproteins', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Plant', 'Genes, Plant', 'Genes, src', 'Mixed Function Oxygenases', 'Molecular Sequence Data', 'Oxygenases', 'Sequence Alignment'] | 10,216,258 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.157.100'], ['E05.393.183'], ['E05.393.220'], ['D12.776.331'], ['G05.308.320'], ['G05.308.375'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.360.340.024.340.375.500.791.570'], ['D08.811.682.690.708'], ['L01.453.245.667'], ['D08.811.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of recombinant human granulocyte-macrophage colony-stimulating factor on myelopoiesis in the acquired immunodeficiency syndrome. | We administered recombinant (biosynthetic) human granulocyte-macrophage colony-stimulating factor (GM-CSF) to 16 patients with the acquired immunodeficiency syndrome (AIDS) and leukopenia (2225 +/- 614 cells per microliter [mean +/- SD]). Each patient first received a single intravenous dose; 48 hours later a 14-day co... | ['Acquired Immunodeficiency Syndrome', 'Adolescent', 'Adult', 'Bone Marrow', 'Drug Evaluation', 'Hematopoiesis', 'Humans', 'Interleukin-3', 'Leukocyte Count', 'Male', 'Recombinant Proteins'] | 3,497,344 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.057'], ['M01.060.116'], ['A15.382.216'], ['E05.290.625', 'E05.337.425'], ['G04.152.825', 'G09.188.343'], ['B01.050.150.900.649.313.988.400.112... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Current status of chronic cough treatment in Chinese children]. | OBJECTIVE: To comprehensively understand the current situation of the treatment of chronic cough in Chinese children and provide evidence for a reasonable standard therapy.METHOD: According to the 2008 Guideline of diagnosis and treatment of chronic cough in children that were formulated by The Subspecialty Group of Re... | ['Adrenal Cortex Hormones', 'Adrenergic beta-2 Receptor Agonists', 'Analysis of Variance', 'Asthma', 'Child', 'Child, Preschool', 'China', 'Chronic Disease', 'Cough', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Follow-Up Studies', 'Histamine H1 Antagonists', 'Humans', 'Hypersensitivity', 'Leukotriene ... | 24,824,384 | [['D06.472.040'], ['D27.505.519.625.050.100.200.200', 'D27.505.696.577.050.100.200.200'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.252.474.164'], ['C23.550.291.500'], ['C08.618... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Lipids and lipoproteins among Ethiopian immigrants: comparison of operations Solomon and Moses. | Lipid and lipoprotein levels and body mass index were compared between two immigrations of Ethiopian Jews to Israel. Those who came in Operation Moses in 1984-85 were survivors of a long trek across hundreds of kilometers and severe food deprivation. Those who immigrated in Operation Solomon in 1991 were bussed from th... | ['Adolescent', 'Adult', 'Body Mass Index', 'Child', 'Emigration and Immigration', 'Ethiopia', 'Female', 'Humans', 'Israel', 'Jews', 'Lipids', 'Lipoproteins', 'Male', 'Middle Aged', 'Time Factors'] | 8,349,449 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['Z01.058.290.120.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.375... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Vital records in the development of injury control research. | Most of the resources of the emergency physician are devoted to persons already injured, with little emphasis on prevention. Analyses of state and local injury statistics are necessary to identify local prevention needs in order to set program priorities. We discuss an example, an analysis of statewide injury fatalitie... | ['African Americans', 'Age Factors', 'Cause of Death', 'Emergencies', 'European Continental Ancestry Group', 'Humans', 'Illinois', 'Sex Factors', 'Vital Statistics', 'Wounds and Injuries'] | 2,923,338 | [['M01.686.508.100.100', 'M01.686.754.100'], ['N05.715.350.075', 'N06.850.490.250'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['M01.686.508.400'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effects of benzodiazepine receptor ligands and ethanol in rats trained to discriminate pregnanolone. | Although GABA(A) receptor positive modulators share many behavioral effects, subtle differences have been detected among their discriminative stimulus effects. The purpose of the present study was to determine the extent of shared discriminative stimulus effects of pregnanolone with various benzodiazepine receptor liga... | ['Animals', 'Benzodiazepinones', 'Central Nervous System Depressants', 'Discrimination Learning', 'Dose-Response Relationship, Drug', 'Ethanol', 'GABA Modulators', 'Hypnotics and Sedatives', 'Lorazepam', 'Male', 'Pregnanolone', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, GABA-A', 'Triazolam'] | 11,164,076 | [['B01.050'], ['D03.633.100.079.080.070'], ['D27.505.696.277', 'D27.505.954.427.210'], ['F02.463.425.280'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.033.375'], ['D27.505.519.625.240.500', 'D27.505.696.577.240.500'], ['D27.505.696.277.350', 'D27.505.954.427.210.350'], ['D03.633.100.079.080.070.450'], ['D04.210.500.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Forearm glucose uptake in cirrhosis and its relationship to glucose tolerance. | 1. Oral glucose-tolerance tests (100 g) were carried out in six patients with stable well-compensated cryptogenic cirrhosis and in 12 control subjects. 2. In confirmation of previous studies, patients with cirrhosis had high post-glucose serum insulin levels and were glucose intolerant (mean incremental glucose area 95... | ['Adult', 'Blood Glucose', 'Female', 'Forearm', 'Glucose', 'Glucose Tolerance Test', 'Growth Hormone', 'Humans', 'Insulin', 'Insulin Resistance', 'Lactates', 'Liver Cirrhosis', 'Male', 'Middle Aged'] | 7,000,417 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['A01.378.800.585'], ['D09.947.875.359.448'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.20... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[An analysis of the clinical characteristics of patients with chronic hepatitis B superinfected with acute hepatitis E]. | OBJECTIVE: To investigate clinical features of the patients with hepatitis B superinfected with acute hepatitis E (AHE).METHODS: Totally 625 consecutive patients enrolled from Dec 2002 to Dec 2006 were studied retrospectively. All of the patients were subclassified into acute hepatitis E group (AHE=437 cases) and Super... | ['Acute Disease', 'Adult', 'Aged', 'DNA, Viral', 'Female', 'Hepatitis B, Chronic', 'Hepatitis E', 'Humans', 'Male', 'Middle Aged', 'Virus Replication'] | 18,322,591 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['D13.444.308.568'], ['C01.221.250.500.100', 'C01.925.256.430.400.100', 'C01.925.440.435.100', 'C06.552.380.350.100', 'C06.552.380.705.437.100'], ['C01.925.440.470', 'C01.925.782.455', 'C06.552.380.705.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Risk Factor Analysis of the Incidence of Subsequent Adjacent Vertebral Fracture After Lumbar Spinal Fusion Surgery with Instrumentation. | OBJECTIVE: This study aimed to evaluate the risk factors for adjacent vertebral compression fractures after lumbar spinal fusion with instrumentation.METHODS: A total of 669 patients who received lumbar instrumented spinal fusion between January 2012 and December 2015 were divided into 2 groups according to whether the... | ['Adult', 'Aged', 'Factor Analysis, Statistical', 'Female', 'Fractures, Compression', 'Humans', 'Incidence', 'Lumbar Vertebrae', 'Lumbosacral Region', 'Male', 'Middle Aged', 'Risk Factors', 'Spinal Fractures', 'Spinal Fusion', 'Treatment Outcome'] | 31,715,415 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['C26.404.195'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['A02.835.232.834.519'], ['A01.923... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of an injectable platelet-rich fibrin on osteoblast behavior and bone tissue formation in comparison to platelet-rich plasma. | Platelet-rich plasma (PRP) has been utilized for many years as a regenerative agent capable of inducing vascularization of various tissues using blood-derived growth factors. Despite this, drawbacks mostly related to the additional use of anti-coagulants found in PRP have been shown to inhibit the wound healing process... | ['Blood Platelets', 'Bone Regeneration', 'Cell Adhesion', 'Cell Differentiation', 'Cell Movement', 'Cell Proliferation', 'Cell Survival', 'Cells, Cultured', 'Humans', 'Osteoblasts', 'Osteogenesis', 'Platelet-Rich Fibrin', 'Platelet-Rich Plasma', 'Wound Healing'] | 28,351,189 | [['A11.118.188', 'A15.145.229.188'], ['G11.427.213.140', 'G16.762.150.150'], ['G04.022'], ['G04.152'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.629'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chemical and statistical interpretation of sized aerosol particles collected at an urban site in Thessaloniki, Greece. | The size distribution of aerosol particles (PM0.015-PM18) in relation to their soluble inorganic species and total water soluble organic compounds (WSOC) was investigated at an urban site of Thessaloniki, Northern Greece. The sampling period was from February to July 2007. The determined compounds were compared with ma... | ['Aerosols', 'Air Movements', 'Air Pollutants', 'Chromatography, Ion Exchange', 'Cluster Analysis', 'Environmental Monitoring', 'Greece', 'Multivariate Analysis', 'Particle Size', 'Particulate Matter', 'Principal Component Analysis', 'Seasons', 'Solubility'] | 24,007,436 | [['D20.280.055', 'D26.255.165.055'], ['G16.500.175.249', 'G16.500.275.063.725.154', 'N06.230.300.100.150.185'], ['D27.888.284.101'], ['E05.196.181.400.383'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['N06.850.460.350.080', 'N06.850.780.375'], ['Z01.542.383'], ['E05.318.740.150.500', 'N05.715.3... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Enzymatic synthesis of solid phase-bound DNA sequences corresponding to specific mammalian genes. | With oligo(dT)-cellulose as primer, RNA-dependent DNA polymerase catalyzes the synthesis of cellulose-bound DNA that is complementary to mouse globin mRNA. The resulting cellulose-bound or solid phase complementary DNA hybridizes specifically with globin mRNA and permits the recovery of intact globin mRNA. This simple ... | ['Animals', 'Avian Myeloblastosis Virus', 'Base Sequence', 'Cellulose', 'Centrifugation, Density Gradient', 'DNA', 'Genes', 'Globins', 'Immunoglobulins', 'In Vitro Techniques', 'Iodine Radioisotopes', 'Mice', 'Nucleic Acid Hybridization', 'Oligonucleotides', 'RNA, Messenger', 'RNA-Directed DNA Polymerase', 'Templates, ... | 4,139,705 | [['B01.050'], ['B04.613.807.070.110', 'B04.820.650.070.110'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['E05.181.724.336', 'E05.196.941.336'], ['D13.444.308'], ['G05.360.340.024.340'], ['D12.776.422.316'], ['D12.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Three-dimensional mapping of cortical thickness using Laplace's equation. | We present a novel, computerized method of examining cerebral cortical thickness. The normal cortex varies in thickness from 2 to 4 mm, reflecting the morphology of neuronal sublayers. Cortical pathologies often manifest abnormal variations in thickness, with examples of Alzheimer's disease and cortical dysplasia as th... | ['Algorithms', 'Brain Mapping', 'Cerebral Cortex', 'Humans', 'Magnetic Resonance Imaging', 'Models, Neurological'] | 10,997,850 | [['G17.035', 'L01.224.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E05.599.395.642']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Glutamate ameliorates experimental vincristine neuropathy. | The dose-limiting toxicity of the chemotherapeutic agent vincristine is peripheral neuropathy, for which there is no established therapy. The amino acid glutamate has been proposed as a neuroprotectant for vincristine, but a full preclinical evaluation of its efficacy, safety and mechanism of action has been hampered b... | ['Animals', 'Antineoplastic Agents, Phytogenic', 'Female', 'Gait', 'Glutamic Acid', 'Motor Activity', 'Neoplasms, Experimental', 'Neuroprotective Agents', 'Peripheral Nervous System Diseases', 'Rats', 'Sensory Thresholds', 'Vincristine'] | 8,859,020 | [['B01.050'], ['D27.505.954.248.179'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['F01.145.632', 'G11.427.410.698'], ['C04.619', 'E05.598.500.496'], ['D27.505.696.706.548', 'D27.505.954.427.575'], ['C10.668.829'], ['B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pharmaceutical and pharmacokinetic evaluation of a novel fast dissolving film formulation of flupentixol dihydrochloride. | The objective of the present study was to develop fast dissolving oral film of the antipsychotic drug, flupentixol dihydrochloride, to enhance its bioavailability, optimize its therapeutic effect when used to treat depression with anxiety, and increase the convenience and compliance by the mentally ill, developmentally... | ['Administration, Oral', 'Adult', 'Antipsychotic Agents', 'Biological Availability', 'Calorimetry, Differential Scanning', 'Carboxymethylcellulose Sodium', 'Chemistry, Pharmaceutical', 'Chromatography, Liquid', 'Excipients', 'Flupenthixol', 'Humans', 'Hypromellose Derivatives', 'Male', 'Reproducibility of Results', 'So... | 25,142,820 | [['E02.319.267.100'], ['M01.060.116'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['G03.787.151', 'G07.690.725.129'], ['E05.196.131.310', 'E05.196.370.310'], ['D09.698.365.180.663.329'], ['H01.158.703.007', 'H01.181.466'], ['E05.196.181.400'], ['D26.650.700.419', 'D27.720... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
Intensity-modulated radiation therapy with concurrent chemotherapy as preoperative treatment for localized gastric adenocarcinoma. | PURPOSE: The goal of this study was to evaluate dosimetric parameters, acute toxicity, pathologic response, and local control in patients treated with preoperative intensity-modulated radiation therapy (IMRT) and concurrent chemotherapy for localized gastric adenocarcinoma.METHODS: Between November 2007 and April 2010,... | ['Adenocarcinoma', 'Adult', 'Aged', 'Anorexia', 'Antineoplastic Combined Chemotherapy Protocols', 'Capecitabine', 'Chemoradiotherapy', 'Dehydration', 'Deoxycytidine', 'Docetaxel', 'Female', 'Fluorouracil', 'Gastrectomy', 'Heart', 'Humans', 'Induction Chemotherapy', 'Kidney', 'Male', 'Middle Aged', 'Nausea', 'Organoplat... | 22,137,021 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['C23.888.821.108'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D03.383.742.680.245.500.425', 'D03.383.742.698.875.404.425', 'D13.570.230.329.313', 'D13.570.685.245.500.425'], ['E02.186.079', 'E02.319.164', 'E02.815.160'], ['C18.452.950.1... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Predation mechanisms of Rapana venosa (Gastropoda: Muricidae) in different biotopes along the Black Sea coast. | Mechanisms of feeding by the invasive gastropod Rapana venosa from different biotopes of 11 sites along the Black Sea coast are discussed. Two methods--edge-drilling and suffocation--are used, but the prevailing method in a particular biotope depends on the type of bivalve prey. Drill signs were present on almost all s... | ['Animals', 'Bivalvia', 'Black Sea', 'Food Chain', 'Gastropoda', 'Introduced Species', 'Predatory Behavior', 'Russia', 'Ukraine'] | 26,242,971 | [['B01.050'], ['B01.050.500.644.080'], ['Z01.756.217'], ['G16.500.275.157.250', 'N06.230.124.250'], ['B01.050.500.644.400'], ['B01.050.050.580', 'G16.500.275.157.049.400', 'N06.230.124.049.400'], ['F01.145.113.111.600', 'F01.145.113.252.520'], ['Z01.252.122.500', 'Z01.542.248.775'], ['Z01.542.248.960', 'Z01.542.931.960... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Runoff transport of pyrethroids from a residential lawn in central California. | An irrigation runoff study on a residential lawn was conducted in California, northeast of Sacramento, during the summer and fall of 2008 to investigate the contribution of turf uses of pyrethroids to residues in Californian urban creek sediments. This study examined how over irrigation (i.e., irrigation that produces ... | ['Animals', 'California', 'Cities', 'Geologic Sediments', 'Insecticides', 'Pyrethrins', 'Seasons', 'Water Movements', 'Water Pollutants, Chemical', 'Water Supply'] | 21,520,766 | [['B01.050'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['G01.311.330', 'G16.500.320'], ['D27.720.031.700.491', 'D27.888.723.491'], ['D02.455.849.575.188.750'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['G16.500.971', 'N06.230.13... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Comparison of measured resting energy expenditure versus predictive equations in pediatric burn patients. | Many equations have been developed to estimate resting energy expenditure (REE) in thermally injured patients. A consensus has not been reached on the accuracy of these equations in children. The purpose of our study was to compare three predictive equations: Harris Benedict x 2 multiplier (HB x 2), Mayes (MG), and the... | ['Basal Metabolism', 'Breath Tests', 'Burns', 'Calorimetry, Indirect', 'Carbon Dioxide', 'Child', 'Child Nutritional Physiological Phenomena', 'Child, Preschool', 'Energy Intake', 'Female', 'Humans', 'Male', 'Nutritional Requirements', 'Oxygen Consumption', 'Retrospective Studies'] | 16,278,559 | [['G03.295.154'], ['E01.370.100'], ['C26.200'], ['E05.196.131.655'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['M01.060.406'], ['G07.203.650.220'], ['M01.060.406.448'], ['G07.203.650.240.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.650.620'], ['G03.680'], ['E05.318.372.500.500.500', 'E05.... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Selectively deposited silver coatings on gold-capped silicon nanowires for surface-enhanced Raman spectroscopy. | Gold caps on silicon nanowires are selectively coated with silver by autometallography (electroless deposition). Changing the conditions of silver deposition, a variety of different coating morphologies can be produced [figure: see text]. The different silver coating morphologies are investigated in terms of their capa... | ['Gold', 'Nanowires', 'Silicon', 'Silver', 'Spectrum Analysis, Raman'] | 19,399,821 | [['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['J01.637.512.925'], ['D01.268.513.937'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.812'], ['E05.196.822.860', 'E05.196.867.890']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Polypharmacy in nursing home residents in the United States: results of the 2004 National Nursing Home Survey. | BACKGROUND: Despite the need for and benefits of medications, polypharmacy (defined here as concurrent use of > or =9 medications) in nursing home residents is a concern. As the number of medications taken increases, so does the risk for adverse events. Monitoring polypharmacy in this population is important and can im... | ['Aged', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Female', 'Health Care Surveys', 'Homes for the Aged', 'Humans', 'Male', 'Middle Aged', 'Nursing Homes', 'Polypharmacy', 'Retrospective Studies', 'United States'] | 20,226,393 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['J03.775.462', 'N02.278.825.462'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Examining the proteins of functional retinal lipofuscin using proteomic analysis as a guide for understanding its origin. | PURPOSE: To elucidate the origins of biologically active retinal lipofuscin (RLF) by examining its protein composition.METHODS: Total protein and total lipid were extracted and quantified. Proteins in this lipoprotein granule were identified by limited-scale proteomic analysis using both two-dimensional (2D) gel electr... | ['Adult', 'Aged', 'Aged, 80 and over', 'Electrophoresis, Gel, Two-Dimensional', 'Electrophoresis, Polyacrylamide Gel', 'Flow Cytometry', 'Humans', 'Lipofuscin', 'Microscopy, Electron, Scanning', 'Microscopy, Immunoelectron', 'Middle Aged', 'Pigment Epithelium of Eye', 'Proteome', 'Proteomics', 'Spectrometry, Fluorescen... | 16,379,024 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.196.401.250', 'E05.301.300.230'], ['E05.196.401.402', 'E05.301.300.319'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Association between metabolic syndrome and intravesical prostatic protrusion in patients with benign prostatic enlargement and lower urinary tract symptoms (MIPS Study). | OBJECTIVE: To investigate the association between metabolic syndrome (MetS) and morphological features of benign prostatic enlargement (BPE), including total prostate volume (TPV), transitional zone volume (TZV) and intravesical prostatic protrusion (IPP).PATIENTS AND METHODS: Between January 2015 and January 2017, 224... | ['Aged', 'Cross-Sectional Studies', 'Humans', 'Lower Urinary Tract Symptoms', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Organ Size', 'Prognosis', 'Prostate', 'Prostatic Hyperplasia'] | 28,872,764 | [['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.942.343'], ['C18.452.394.968.500.570', 'C18.452.625'], ['M01.060.116.630'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Clinical score and arterial oxygen saturation in children with wheezing associated respiratory illness (WARI). | OBJECTIVES: To determine the correlation between clinical score (based on respiratory rate, chest wall retractions, air entry, wheezing, consciousness and audible wheezing) and arterial oxygen saturation (SaO2: measured by pulse oximetry) as well as the most appropriate total score for predicting hypoxemia (SaO2 < or =... | ['Child, Preschool', 'Cross-Sectional Studies', 'Diagnosis, Differential', 'Female', 'Humans', 'Hypoxia', 'Infant', 'Infant, Newborn', 'Linear Models', 'Male', 'Oximetry', 'Oxygen', 'Predictive Value of Tests', 'ROC Curve', 'Respiratory Physiological Phenomena', 'Respiratory Sounds', 'Respiratory Tract Diseases', 'Seve... | 11,143,488 | [['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.079'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effect of grandmultiparity on pregnancy related complications: the Aga Khan University experience. | BACKGROUND: Grandmultiparity has been associated with complications for both mother and the fetus.OBJECTIVE: To evaluate if grandmultiparity is a risk factor in the presence of adequate antenatal care.SETTING: A tertiary care teaching hospital.METHODS: It was a retrospective study conducted in the department of Obstetr... | ['Adult', 'Birth Weight', 'Female', 'Humans', 'Logistic Models', 'Maternal Age', 'Parity', 'Postpartum Hemorrhage', 'Pregnancy', 'Pregnancy Complications', 'Pregnancy Outcome', 'Prevalence', 'Retrospective Studies', 'Risk Factors'] | 10,769,523 | [['M01.060.116'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.48... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
(Butylthio)carbonyl group: a new protecting group for the guanine and uracil residues in oligoribonucleotide synthesis. | The protection of the O6-amide and N2-amino groups of guanosine and the N3-imide group of uridine with the (butylthio)carbonyl group is described. This group could be rapidly introduced in good yields and removed very easily under the conventional deprotective conditions of the exo-amino acyl groups of other nucleoside... | ['Base Sequence', 'Guanine', 'Indicators and Reagents', 'Molecular Structure', 'Oligoribonucleotides', 'Uracil'] | 3,226,925 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D03.633.100.759.758.399.454'], ['D27.720.470.410'], ['G02.111.570', 'G02.466'], ['D13.695.578.424.500'], ['D03.383.742.698.875']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of Larval Density on Food Utilization Efficiency of Tenebrio molitor (Coleoptera: Tenebrionidae). | Crowding conditions of larvae may have a significant impact on commercial production efficiency of some insects, such as Tenebrio molitor L. (Coleoptera: Tenebrionidae). Although larval densities are known to affect developmental time and growth in T. molitor, no reports were found on the effects of crowding on food ut... | ['Animals', 'Biomass', 'Crowding', 'Feeding Behavior', 'Larva', 'Population Density', 'Tenebrio', 'Time Factors'] | 26,453,714 | [['B01.050'], ['G16.500.275.157.100', 'N06.230.124.100'], ['F01.145.875.281'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B05.500.500', 'G07.345.500.550.500.500'], ['N01.224.600', 'N06.850.505.400.600'], ['B01.050.500.131.617.720.500.500.375.615'], ['G01.910.857']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
miR26a modulates Th17/T reg balance in the EAE model of multiple sclerosis by targeting IL6. | A number of different microRNAs (miRNAs) have been implicated in various autoimmune diseases, including multiple sclerosis (MS). T helper (Th)17 and regulatory T cells (Tregs) have likewise been implicated as key players in MS, and a functional imbalance of these cell types is increasingly recognized as a key etiologic... | ["3' Untranslated Regions", 'Animals', 'DNA, Recombinant', 'Down-Regulation', 'Encephalomyelitis, Autoimmune, Experimental', 'Gene Expression Regulation', 'Genetic Vectors', 'HEK293 Cells', 'Humans', 'Interleukin-6', 'Lentivirus', 'Mice', 'Mice, Inbred C57BL', 'MicroRNAs', 'Multiple Sclerosis, Relapsing-Remitting', 'RN... | 25,362,566 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['B01.050'], ['D13.444.308.460'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.314.350.250', 'C20.111.258.625.300', 'E05.598.500.500.500'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The spectrum of perianal Crohn's disease in a population-based cohort. | BACKGROUND: Perianal Crohn's disease represents a phenotype distinct from luminal Crohn's disease and may follow a different course. To date, the only detailed classifications of perianal Crohn's disease arise from referral center cohorts that do not reflect the spectrum of disease in the population as a whole.OBJECTIV... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anus Diseases', 'Child', 'Child, Preschool', 'Cohort Studies', 'Crohn Disease', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'New Zealand', 'Retrospective Studies', 'Time Factors', 'Young Adult'] | 22,706,129 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C06.405.469.860.101'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['C23.550.291.656'], ['E05.318.372.500.750.249', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Transfer of median and ulnar nerve fascicles for lesions of the posterior cord in infraclavicular brachial plexus injury: report of 2 cases. | In infraclavicular lesions of brachial plexus, severe lesions of the posterior cord often occur when medial and lateral cord function is preserved to a greater or lesser extent. In these cases, shoulder function may be preserved by activity of the muscles innervated by the suprascapular nerve, but complete paralysis ex... | ['Adolescent', 'Adult', 'Brachial Plexus', 'Humans', 'Hypesthesia', 'Male', 'Median Nerve', 'Muscle, Skeletal', 'Nerve Transfer', 'Paralysis', 'Ulnar Nerve'] | 23,021,172 | [['M01.060.057'], ['M01.060.116'], ['A08.800.800.720.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.751.791.500', 'C23.888.592.763.770.500'], ['A08.800.800.720.050.500'], ['A02.633.567', 'A10.690.552.500'], ['E04.525.550'], ['C10.597.622', 'C23.888.592.636'], ['A08.800.800.720.050.850']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Competing formate- and carbon dioxide-utilizing prokaryotes in an anoxic methane-emitting fen soil. | Methanogenesis in wetlands is dependent on intermediary substrates derived from the degradation of biopolymers. Formate is one such substrate and is stimulatory to methanogenesis and acetogenesis in anoxic microcosms of soil from the fen Schl?ppnerbrunnen. Formate dissimilation also yields CO(2) as a potential secondar... | ['Anaerobiosis', 'Biodiversity', 'Carbon Dioxide', 'Carbon Isotopes', 'Cluster Analysis', 'DNA, Archaeal', 'DNA, Bacterial', 'DNA, Ribosomal', 'Formates', 'Genes, rRNA', 'Methane', 'Molecular Sequence Data', 'Phylogeny', 'RNA, Archaeal', 'RNA, Bacterial', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Sequence Homol... | 21,478,308 | [['G02.111.062', 'G03.078'], ['G16.500.275.157.049', 'N06.230.124.049'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D01.268.150.075', 'D01.496.123'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['D13.444.308.180'], ['D13.444.308.212'], ['D13.444.308.475'], ['D02.241.081.420'], ['G05.360... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Longitudinal follow-up of patients with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. | BACKGROUND AND OBJECTIVES: Although immunochemotherapy has been reported to be an effective initial treatment for patients with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH), the long-term outcome of these patients remains unknown. The main purpose of this study was to determine the outcome... | ['Adolescent', 'Cause of Death', 'Child', 'Child, Preschool', 'Cohort Studies', 'Combined Modality Therapy', 'Cord Blood Stem Cell Transplantation', 'Dexamethasone', 'Drug Therapy, Combination', 'Epstein-Barr Virus Infections', 'Etoposide', 'Female', 'Follow-Up Studies', 'Herpesvirus 4, Human', 'Histiocytosis, Non-Lang... | 15,003,893 | [['M01.060.057'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E02.186'], ['E02.095.147.500.500.312', 'E04.936.225.687.312'], ['D04.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Ecotoxicological risk of pharmaceuticals from wastewater treatment plants in Korea: occurrence and toxicity to Daphnia magna. | The overall ecotoxicological effect of pharmaceutically active compounds (PhACs) detected in the effluents of Korean wastewater treatment plants (WWTPs) to Daphnia magna was investigated using biological and chemical analyses. The bioassay results showed median lethal concentrations and no-observed-effect concentration... | ['Animals', 'Daphnia', 'Drug-Related Side Effects and Adverse Reactions', 'Environmental Monitoring', 'Korea', 'Lethal Dose 50', 'No-Observed-Adverse-Effect Level', 'Pharmaceutical Preparations', 'Reproduction', 'Risk Assessment', 'Sewage', 'Waste Disposal, Fluid', 'Water Pollutants, Chemical'] | 16,494,251 | [['B01.050'], ['B01.050.500.131.365.150.200'], ['C25.100'], ['N06.850.460.350.080', 'N06.850.780.375'], ['Z01.252.474.557', 'Z01.586.407'], ['E05.940.402', 'G07.225.500', 'G07.690.773.875.750', 'G07.690.936.500.750'], ['E05.940.600', 'G07.690.936.750'], ['D26'], ['G08.686.784'], ['E05.318.740.600.800.715', 'N04.452.871... | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Vascularized fibular epiphyseal transfer for proximal humeral reconstruction in children with a primary sarcoma of bone. | Aims: Preserving growth following limb-salvage surgery of the upper limb in children remains a challenge. Vascularized autografts may provide rapid biological incorporation with the potential for growth and longevity. In this study, we aimed to describe the outcomes following proximal humeral reconstruction with a vasc... | ['Bone Neoplasms', 'Bone Transplantation', 'Child', 'Child, Preschool', 'Female', 'Fibula', 'Follow-Up Studies', 'Humans', 'Humerus', 'Limb Salvage', 'Male', 'Osteosarcoma', 'Retrospective Studies', 'Sarcoma, Ewing', 'Survival Analysis', 'Treatment Outcome'] | 29,629,581 | [['C04.588.149', 'C05.116.231'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['M01.060.406'], ['M01.060.406.448'], ['A02.835.232.043.650.321'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.087.090... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Vasorelaxant effects of Cerebralcare Granule® are mediated by NO/cGMP pathway, potassium channel opening and calcium channel blockade in isolated rat thoracic aorta. | ETHNOPHARMACOLOGICAL RELEVANCE: Cerebralcare Granule (CG), one of the famous classical recipes in traditional Chinese medicine, is developed from the "Decoction of Four Drugs". It has been used for treatment of cerebrovascular related diseases, such as hypertension. It is well known that vasodilatation plays a very imp... | ['Animals', 'Aorta, Thoracic', 'Calcium', 'Calcium Channel Blockers', 'Calcium Channels', 'Cyclic GMP', 'Dose-Response Relationship, Drug', 'Drugs, Chinese Herbal', 'Endothelium, Vascular', 'KATP Channels', 'Male', 'Nitric Oxide', 'Potassium Channels', 'Rats', 'Rats, Wistar', 'Vasodilation', 'Vasodilator Agents'] | 24,924,524 | [['B01.050'], ['A07.015.114.056.372'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160'... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical inconsistency, benign course and normal employment rates in unselected systemic lupus erythematosus. | Of 65 unselected SLE patients from a defined population, 61 were sequentially followed for two years with an SLE supervision programme. The cumulative clinical manifestations included a relatively high frequency of pulmonary vascular disease and gastrointestinal involvement. Flares were more common during the summer se... | ['Adult', 'Aged', 'Antibodies, Antinuclear', 'Bacterial Infections', 'Complement System Proteins', 'Employment', 'Female', 'Humans', 'Lupus Erythematosus, Systemic', 'Male', 'Middle Aged', 'Pregnancy', 'Work Capacity Evaluation'] | 3,878,760 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['C01.150.252'], ['D12.776.124.486.274'], ['N01.824.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.300.480', 'C20.111.590'], ['M01.060.116.630'], ['G08.686.784... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impaired down-regulation of negative emotion in self-referent social situations in bipolar disorder: A pilot study of a novel experimental paradigm. | Emotion dysregulation is a core feature of bipolar disorder (BD) that persists into periods of remission. Neuroimaging studies show aberrant neural responses during emotion regulation (ER) in patients with BD relative to healthy controls, but behavioural evidence for ER deficits is sparse and conflicting. This study ai... | ['Adult', 'Affective Symptoms', 'Bipolar Disorder', 'Case-Control Studies', 'Down-Regulation', 'Emotions', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pilot Projects'] | 27,086,251 | [['M01.060.116'], ['F01.145.126.100'], ['F03.084.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Eosinophilic pustular folliculitis. Studies on possible chemotactic factors involved in the formation of pustules. | Eosinophilic pustular folliculitis (EPF) is a dermatosis of unknown aetiology, characterized by repeated development of pruritic follicular papulopustules with a tendency to form an annular configuration on the face and other seborrhoeic areas, and by palmoplantar pustular lesions in one-fifth of the patients. Both typ... | ['Adult', 'Chemotactic Factors', 'Chemotactic Factors, Eosinophil', 'Chemotaxis, Leukocyte', 'Eosinophilia', 'Female', 'Folliculitis', 'Humans', 'Male', 'Neutrophils', 'Skin', 'Skin Diseases, Vesiculobullous'] | 3,511,943 | [['M01.060.116'], ['D23.125'], ['D23.125.320'], ['G04.198.424.233'], ['C15.378.553.231'], ['C17.800.329.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['A17.815'], ['C17.800.865']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reprogramming of somatic cells: iPS and iN cells. | Limited access to human neurons has posed a significant barrier to progress in biological and preclinical studies of the human nervous system. The advent of cell reprogramming technologies has widely disclosed unprecedented opportunities to generate renewable sources of human neural cells for disease modeling, drug dis... | ['Cell Differentiation', 'Cellular Reprogramming', 'Humans', 'Induced Pluripotent Stem Cells', 'Neurons', 'Transcription Factors'] | 28,552,235 | [['G04.152'], ['G04.152.262', 'G05.135'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.872.040.500', 'A11.872.700.500'], ['A08.675', 'A11.671'], ['D12.776.930']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
NK1R/5-HT1AR interaction is related to the regulation of melanogenesis. | Substance P (SP) is a candidate mediator along the brain-skin axis and can mimic the effects of stress to regulate melanogenesis. Previously, we and others have found that the regulation of SP for pigmentary function was mediated by neurokinin 1 receptor (NK1R). Emerging evidence has accumulated that psychologic stress... | ['Animals', 'Cell Line, Tumor', 'HEK293 Cells', 'Humans', 'Melanins', 'Mice', 'Neurokinin-1 Receptor Antagonists', 'Piperazines', 'Pyridines', 'Receptor, Serotonin, 5-HT1A', 'Receptors, Neurokinin-1', 'Serotonin 5-HT1 Receptor Antagonists', 'Skin', 'Skin Pigmentation', 'Stress, Psychological', 'Substance P', 'Zebrafish... | 29,430,989 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.125.072.050.875.379', 'D23.767.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['D27.505.519.625.487', 'D27.505.696.577.487'], ['D03.383.606'], ['D03.383.725'], ['D12.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intraclonal protein expression heterogeneity in recombinant CHO cells. | Therapeutic glycoproteins have played a major role in the commercial success of biotechnology in the post-genomic era. But isolating recombinant mammalian cell lines for large-scale production remains costly and time-consuming, due to substantial variation and unpredictable stability of expression amongst transfected c... | ['Animals', 'CHO Cells', 'Cell Cycle', 'Cell Shape', 'Cell Size', 'Clone Cells', 'Cricetinae', 'Cricetulus', 'Flow Cytometry', 'Fluorescence', 'Humans', 'Immunoglobulin G', 'Recombination, Genetic'] | 20,037,651 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['G04.144'], ['G04.320'], ['G04.325'], ['A11.251.353'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.50... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bacterial and protozoal pathogens found in ticks collected from humans in Corum province of Turkey. | BACKGROUND: Tick-borne diseases are increasing all over the word, including Turkey. The aim of this study was to determine the bacterial and protozoan vector-borne pathogens in ticks infesting humans in the Corum province of Turkey.METHODOLOGY/PRINCIPAL FINDINGS: From March to November 2014 a total of 322 ticks were co... | ['Anaplasma', 'Animals', 'Arachnid Vectors', 'Babesia', 'Bartonella', 'Ehrlichia', 'Humans', 'Ixodidae', 'Rickettsia', 'Tick-Borne Diseases', 'Turkey'] | 29,649,265 | [['B03.440.664.750.050', 'B03.660.050.783.500.050'], ['B01.050'], ['N06.850.335.188.100.100', 'N06.850.520.203.375.100.100'], ['B01.043.075.600.580.070'], ['B03.440.090.100', 'B03.660.050.030.040'], ['B03.440.664.750.287', 'B03.660.050.783.500.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.500.131.16... | ['Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Effects of ethanol on muscarinic receptor-stimulated phosphoinositide metabolism during brain development. | The pattern of muscarinic receptor-stimulated inositol metabolism during postnatal development has a striking resemblance with the curve of rat brain growth spurt. Therefore, the enhanced hydrolysis of membrane inositol lipids by cholinergic agonists during this period may have a relevant role in cell proliferation and... | ['Animals', 'Animals, Newborn', 'Brain', 'Carbachol', 'Ethanol', 'Female', 'Phosphatidylinositols', 'Pregnancy', 'Quinuclidinyl Benzilate', 'Rats', 'Receptors, Muscarinic'] | 2,547,937 | [['B01.050'], ['B01.050.050.282'], ['A08.186.211'], ['D02.092.877.883.333.115', 'D02.675.276.232.115'], ['D02.033.375'], ['D10.570.755.375.760.400.942'], ['G08.686.784.769'], ['D02.241.223.601.238.306.740', 'D02.241.511.085.740', 'D03.605.687.800'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.543.750.695.475... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.