Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Polyethylenimine coated plasmid DNA-surfactant complexes as potential gene delivery systems. | Nanometer scaled particles have been prepared from strong association between plasmid DNA (pcDNA3-FLAG-p53) and oppositely charged surfactants. Although these particles present suitable properties for gene delivery purposes, their cytotoxicity could compromise their use in gene therapy applications. To ensure biocompat... | ['DNA', 'Plasmids', 'Polyethyleneimine', 'Surface-Active Agents', 'Transfection'] | 26,099,970 | [['D13.444.308'], ['G05.360.600'], ['D02.455.326.271.665.550.600', 'D02.491.650', 'D05.750.716.507.600', 'D25.720.716.507.600', 'J01.637.051.720.716.507.600'], ['D27.720.877'], ['E05.393.350.810', 'G05.728.860']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy. | OBJECTIVE: Variants in neuronal voltage-gated sodium channel á-subunits genes SCN1A, SCN2A, and SCN8A are common in early onset epileptic encephalopathies and other autosomal dominant childhood epilepsy syndromes. However, in clinical practice, missense variants are often classified as variants of uncertain significanc... | ['Algorithms', 'Computer Simulation', 'DNA Mutational Analysis', 'Databases, Genetic', 'Epilepsy', 'Genetic Predisposition to Disease', 'Genetic Variation', 'Humans', 'Infant', 'Mutation, Missense', 'NAV1.1 Voltage-Gated Sodium Channel', 'NAV1.2 Voltage-Gated Sodium Channel', 'NAV1.6 Voltage-Gated Sodium Channel', 'Phe... | 28,518,218 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['E05.393.760.700.300'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['C10.228.140.490'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G05.365.590.650'], ['D12.776.157.530.400.875.75... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Early-life exposure to artificial light at night elevates physiological stress in free-living songbirds? | Artificial light at night (ALAN) can disrupt adaptive patterns of physiology and behavior that promote high fitness, resulting in physiological stress and elevation of steroid glucocorticoids (corticosterone, CORT in birds). Elevated CORT may have particularly profound effects early in life, with the potential for endu... | ['Animals', 'Corticosterone', 'Environmental Exposure', 'Feathers', 'Light', 'Songbirds', 'Stress, Physiological'] | 31,926,393 | [['B01.050'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['N06.850.460.350'], ['A13.370'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['B01.050.150.900.248.620.750'], ['G07.775']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Prostatic arterial embolization to treat benign prostatic hyperplasia. | PURPOSE: To evaluate whether prostatic arterial embolization (PAE) might be a feasible procedure to treat lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH).MATERIALS AND METHODS: Fifteen patients (age range, 62-82 years; mean age, 74.1 y) with symptomatic BPH after failure of medical treat... | ['Aged', 'Aged, 80 and over', 'Arteries', 'Biopsy', 'Embolization, Therapeutic', 'Feasibility Studies', 'Humans', 'Ischemia', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Organ Size', 'Penile Erection', 'Pilot Projects', 'Polyvinyl Alcohol', 'Portugal', 'Prospective Studies', 'Prostate', 'Prostate-Specific Ant... | 21,195,898 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A07.015.114'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E02.520.360', 'E02.926.500'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'],... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Anthropology, Education, Sociology,... | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
[Plasma technologies in surgery of pulmonary echinococcosis]. | 178 patients were operated over 18 years for pulmonary echinococcosis, 100 of them with standard methods, 78--with plasma technologies (surgical device SUPR-2M). Close echinococcectomy was performed in 22.5% patients, open--in 69.1%, combination of these operations--in 8.4% patients. Plasma technologies were used at pn... | ['Adult', 'Echinococcosis, Pulmonary', 'Female', 'Humans', 'Male', 'Middle Aged', 'Plasmapheresis', 'Pulmonary Medicine', 'Pulmonary Surgical Procedures', 'Thoracotomy'] | 11,875,944 | [['M01.060.116'], ['C01.610.335.190.396.480', 'C01.610.582.314', 'C01.748.450.314', 'C08.381.517.314', 'C08.730.450.314'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.120.770', 'E02.912.715', 'E04.292.869'], ['H02.403.429.675'], ['E04.928.600'], ['E04.928.760']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Adjustment of permissible exposure values to unusual work schedules. | Research activities sought development of a method to adjust exposure limits for 694 substances for unusual work schedules. A consensus was established on the basic toxicological principle for adjustment; criteria for adjustment were selected by a panel of scientists coordinated by a committee of international experts ... | ['Guideline Adherence', 'Hazardous Substances', 'Humans', 'Models, Theoretical', 'Occupational Medicine', 'Threshold Limit Values', 'Time Factors', 'Work Schedule Tolerance'] | 11,669,384 | [['N04.761.337', 'N05.715.360.395'], ['D27.888.426'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['H02.403.720.750.510'], ['N03.706.615.917', 'N06.850.460.350.600.807'], ['G01.910.857'], ['I03.946.225.375', 'N04.452.677.650.375']] | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Characterization and phosphorylation of CREB-like proteins in Aplysia central nervous system. | Studies in Aplysia californica indicate that cAMP-mediated gene expression is necessary for long-term facilitation, a correlate of long-term memory. It has been shown that blocking the expression of cAMP-inducible genes in sensory neurons impedes long-term facilitation without any effect on short-term facilitation. Spe... | ['Animals', 'Aplysia', 'Blotting, Western', 'Central Nervous System', 'Cyclic AMP', 'Long-Term Potentiation', 'Phosphorylation', 'Proteins', 'Rats'] | 8,804,712 | [['B01.050'], ['B01.050.500.644.400.060'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A08.186'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['G11.561.638.350'], ['G02.111.665', 'G02.607.780', 'G03.796'], [... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessment tool assists in complying with many JCAHO standards. | How a Pennsylvania medical center found a unique and time-saving approach to satisfying compliance with JCAHO's Management of the Environment of Care standards. Several members of the Safety Committee and the Education Resources Department developed a 25-question quiz, the "Safety Challenge Assessment Tool," to see wha... | ['Health Facility Environment', 'Hospital Administration', 'Humans', 'Inservice Training', 'Joint Commission on Accreditation of Healthcare Organizations', 'Medical Waste Disposal', 'Needlestick Injuries', 'Occupational Health', 'Pennsylvania', 'Safety Management'] | 10,173,426 | [['N02.278.220', 'N05.300.430.400'], ['H02.309', 'N02.278.216.500', 'N04.452.442.452'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['N03.706.110.070.410', 'N05.700.200.100.420'], ['D20.944.460.300', 'N06.850.460.710.460.300', 'N06.850.860.510.900.600.600'], ['C26.986.950.500'], ['N01.400.525'], ['Z01... | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Fetal renal vein thrombosis, hydrops fetalis, and maternal lupus anticoagulant. A case report. | Hydrops fetalis with fetal renal vein thrombosis in a mother with antiphospholipid antibody syndrome detected post-partum suggests an underlying pathogenetic association that may provide new strategies for treatment of a lethal disorder. | ['Adult', 'Antiphospholipid Syndrome', 'Female', 'Fetal Diseases', 'Humans', 'Hydrops Fetalis', 'Immunity, Maternally-Acquired', 'Infant, Newborn', 'Lupus Coagulation Inhibitor', 'Pregnancy', 'Pregnancy Complications', 'Renal Veins', 'Thrombosis', 'Ultrasonography, Prenatal'] | 7,845,897 | [['M01.060.116'], ['C20.111.197'], ['C13.703.277', 'C16.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.703.277.060.480', 'C15.378.295.480', 'C15.378.420.826.100.350', 'C16.300.060.480', 'C16.320.365.826.100.350', 'C20.306.480', 'C23.888.277.395'], ['G12.450.570'], ['M01.060.703.520'], ['D12.776.124.486.4... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Expression levels and co‑targets of miRNA‑126‑3p and miRNA‑126‑5p in lung adenocarcinoma tissues: Án exploration with RT‑qPCR, microarray and bioinformatic analyses. | Lung adenocarcinoma (LUAD) is the most common histological subtype of lung cancer. Previous studies have found that many microRNAs (miRNAs), including miRNA‑126‑3p, may play a critical role in the development of LUAD. However, no study of LUAD has researched the synergistic effects and co‑targets of both miRNA‑126‑3p a... | ['Adenocarcinoma of Lung', 'Biomarkers, Tumor', 'Cell Proliferation', 'Computational Biology', 'Datasets as Topic', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lung', 'Lung Neoplasms', 'MicroRNAs', 'Real-Time Polymerase Chain Reaction', 'Software', 'Tissue Array Analysis'] | 30,535,503 | [['C04.557.470.200.025.022', 'C04.588.894.797.520.055'], ['D23.101.140'], ['G04.161.750', 'G07.345.249.410.750'], ['H01.158.273.180', 'L01.313.124'], ['E05.318.308.056', 'L01.313.500.750.300.188.400.500', 'L01.399.250.224', 'L01.470.750.750.431', 'N05.715.360.300.224', 'N06.850.520.308.056'], ['G05.308.370'], ['B01.050... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
New paths of cyanogenesis from enzymatic-promoted cleavage of â-cyanoglucosides are suggested by a mixed DFT/QTAIM approach. | Cyanogenesis is an enzyme-promoted cleavage of â-cyanoglucosides; the release of hydrogen cyanide is believed to produce food poisoning by consumption of certain crops as Cassava (Manihot esculenta Crantz). The production of hydrogen cyanide by some disruption of the plant wall is related to the content of two â-cyanog... | ['Biocatalysis', 'Biotransformation', 'Glucosides', 'Hydrogen Cyanide', 'Kinetics', 'Manihot', 'Molecular Structure', 'Nitriles', 'Plant Tubers', 'Quantum Theory', 'Thermodynamics'] | 31,478,108 | [['G02.111.086', 'G02.130.500', 'G03.105'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['D09.408.348'], ['D01.029.260.330', 'D01.625.400'], ['G01.374.661', 'G02.111.490'], ['B01.650.940.800.575.912.250.859.797.438.535'], ['G02.111.570', 'G02.466'], ['D02.626'], ['A18.400.625'], ['H01.671.579.800'], ['G01.906']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
What's Ub chain linkage got to do with it? | Ubiquitination-the covalent conjugation of ubiquitin (Ub) to other cellular proteins-regulates a wide range of cellular processes. Often, multiple Ub molecules are added to the substrate to form a Ub chain. Distinct outcomes have been observed for substrates modified with multi-Ub chains linked through particular lysin... | ['Carrier Proteins', 'Models, Biological', 'Proteasome Endopeptidase Complex', 'Protein Processing, Post-Translational', 'Signal Transduction', 'Ubiquitin'] | 16,608,998 | [['D12.776.157'], ['E05.599.395'], ['D05.500.562.500', 'D08.811.277.656.918', 'D08.811.600.730'], ['G02.111.660.871.790.600', 'G02.111.691.600', 'G03.734.871.790.600', 'G05.308.670.600'], ['G02.111.820', 'G04.835'], ['D12.776.947.500']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Screening of malignant hyperthermia susceptible families by creatine phosphokinase measurement and other clinical investigations. | We investigated 56 families afflicted with malignant hyperpyrexia. One hundred and twenty-four individuals within these families had had an episode of malignant hyperthermia, of whom we saw seventy-two. Serum creatine phosphokinase (CPK) was statistically higher in affected individuals and in close relatives than in no... | ['Creatine Kinase', 'Humans', 'Malignant Hyperthermia', 'Pedigree'] | 938,964 | [['D08.811.913.696.640.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.505.700', 'C23.550.767.600'], ['E05.393.673']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Factors contributing to the incompatibility between simplified-step adhesives and chemically-cured or dual-cured composites. Part III. Effect of acidic resin monomers. | PURPOSE: This study examined the polymerization kinetics of acid-contaminated light- and chemically-cured resins with the use of differential scanning calorimetry.MATERIALS AND METHODS: Light-cured and chemically-cured versions of an experimental bis-GMA/TEG-DMA resin at the ratio (w:w) of 62:38 were prepared. Four aci... | ['Acids', 'Benzenesulfonates', 'Bisphenol A-Glycidyl Methacrylate', 'Calorimetry, Differential Scanning', 'Carboxylic Acids', 'Composite Resins', 'Dentin-Bonding Agents', 'Ethylene Glycol', 'Humans', 'Hydrogen-Ion Concentration', 'Light', 'Methacrylates', 'Permeability', 'Polyethylene Glycols', 'Polymers', 'Polymethacr... | 15,008,334 | [['D01.029'], ['D02.455.426.559.389.097', 'D02.886.645.600.080.050.100'], ['D02.241.081.069.600.150', 'D02.455.426.559.389.657.100', 'D05.750.716.822.308.200', 'D25.339.816.500.200', 'D25.720.716.822.308.200', 'J01.637.051.339.816.500.200', 'J01.637.051.720.716.822.308.200'], ['E05.196.131.310', 'E05.196.370.310'], ['D... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Complement activation by the alternative pathway is modified in renal failure: the role of factor D. | Factor D, an essential enzyme of the alternative pathway (AP) of complement, is eliminated by the kidney, and its plasma concentration increases 10-fold in end-stage renal disease (ESRD). The purpose of this study was to analyze the consequences of factor D accumulation. A number of in vitro assays were used to analyze... | ['Aged', 'Aged, 80 and over', 'Complement Activating Enzymes', 'Complement C3', 'Complement C3b', 'Complement C5a', 'Complement Factor D', 'Complement Pathway, Alternative', 'Humans', 'Kidney Failure, Chronic', 'Middle Aged'] | 2,805,459 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.277.300', 'D12.776.124.486.274.045'], ['D12.776.124.050.140', 'D12.776.124.486.274.250'], ['D12.776.124.486.274.250.260'], ['D12.776.124.486.274.024.270', 'D12.776.124.486.274.450.250'], ['D08.811.277.300.450', 'D08.811.277.656.300.760.200', 'D08.811.277.656.959.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Astroglial proliferation and phenotype are modulated by neuronal plasma membrane. | The rate of proliferation of rat astroglia cultured in a serum-free medium, estimated by tritiated thymidine radioautography, was diminished by more than 50% by addition of rat central nervous system axolemmal fragments to the culture medium. Addition of the axolemmal fragments also induced a phenotypic alteration of t... | ['Animals', 'Astrocytes', 'Axons', 'Brain', 'Cell Adhesion', 'Cell Communication', 'Cell Division', 'Cell Membrane', 'Cells, Cultured', 'Corpus Callosum', 'Female', 'Rats', 'Rats, Inbred Strains'] | 6,518,388 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['A08.186.211'], ['G04.022'], ['G04.085'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.284.149'], ['A11.251'], ['A08.186.211.200.885.800.750'], ['B01.050.150.900.64... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lactic acid production directly from starch in a starch-controlled fed-batch operation using Lactobacillus amylophilus. | Based on the batch results, we constructed a simplified simultaneous saccharification and fermentation (SSF) model for the simulation of lactic acid production directly from unhydrolyzed potato starch using Lactobacillus amylophilus. The results of batch operation at different initial starch concentrations (20, 40 and ... | ['Biochemistry', 'Biomass', 'Bioreactors', 'Fermentation', 'Glucose', 'Hydrolysis', 'Industrial Microbiology', 'Kinetics', 'Lactic Acid', 'Lactobacillus', 'Models, Statistical', 'Solanum tuberosum', 'Starch', 'Temperature', 'Time Factors'] | 20,373,112 | [['H01.158.201', 'H01.181.122'], ['G16.500.275.157.100', 'N06.230.124.100'], ['E07.115', 'J01.897.120.115'], ['G02.111.158.249', 'G03.191.249'], ['D09.947.875.359.448'], ['G02.380'], ['H01.158.273.540.460', 'J01.897.120.460'], ['G01.374.661', 'G02.111.490'], ['D02.241.511.459.450'], ['B03.353.750.450.475', 'B03.510.460... | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Peak power, ground reaction forces, and velocity during the squat exercise performed at different loads. | This study examined the changes in peak power, ground reaction force and velocity with different loads during the performance of the parallel squat movement. Twelve experienced male lifters (26.83 +/- 4.67 years of age) performed the standard parallel squat, using loads equal to 20, 30, 40, 50, 60, 70, 80, and 90% of 1... | ['Acceleration', 'Adult', 'Analysis of Variance', 'Biomechanical Phenomena', 'Humans', 'Male', 'Middle Aged', 'Muscle Strength', 'Weight Lifting'] | 16,937,981 | [['G01.482.107'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.600.425', 'G11.427.560'], ['I03.450.642.845.950']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Long-term effects of cyclosporine A in Alport's syndrome. | BACKGROUND: In 1991, our initial results of cyclosporine A (CsA) administration in eight patients with Alport's syndrome were published. A significant decrease in or disappearance of proteinuria and apparently good tolerance to CsA were observed in all patients.METHODS: CsA administration has been maintained in these e... | ['Adolescent', 'Adult', 'Creatinine', 'Cyclosporine', 'Female', 'Humans', 'Kidney', 'Kidney Failure, Chronic', 'Male', 'Microscopy, Electron', 'Nephritis, Hereditary', 'Proteinuria', 'Time Factors'] | 10,027,943 | [['M01.060.057'], ['M01.060.116'], ['D03.383.129.308.207'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E01.370.350.515.402', 'E05.595.402'], ['C12.706.742', 'C12.777.419.570.620', 'C13.35... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Impact of human immunodeficiency virus infection on the prevalence and severity of steatosis in patients with chronic hepatitis C virus infection. | BACKGROUND/AIMS: Although steatosis is strongly associated with hepatitis C virus (HCV) infection, little is known about this finding in patients coinfected with human immunodeficiency virus (HIV) and HCV. The aims of the present study were to determine the prevalence and severity of steatosis in HIV/HCV coinfected pat... | ['Fatty Liver', 'Female', 'HIV Infections', 'Hepatitis C, Chronic', 'Humans', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Prevalence', 'United States'] | 16,618,518 | [['C06.552.241'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C0... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Autocrine expression and ontogenetic functions of the PACAP ligand/receptor system during sympathetic development. | The superior cervical ganglion (SCG) is a well-characterized model of neural development, in which several regulatory signals have been identified. Vasoactive intestinal peptide (VIP) has been found to regulate diverse ontogenetic processes in sympathetics, though functional requirements for high peptide concentrations... | ['Animals', 'Cell Survival', 'Cells, Cultured', 'Cyclic AMP', 'DNA', 'Gene Expression Regulation, Developmental', 'Ligands', 'Mitosis', 'Neurites', 'Neuropeptides', 'Pituitary Adenylate Cyclase-Activating Polypeptide', 'RNA, Messenger', 'Rats', 'Receptor, trkA', 'Receptors, Pituitary Adenylate Cyclase-Activating Polype... | 10,694,416 | [['B01.050'], ['G04.346'], ['A11.251'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D13.444.308'], ['G05.308.310'], ['D27.720.470.480'], ['G04.144.220.220.781', 'G05.113.220.781'], ['A08.675.256.500', 'A08.675.542.145.500', 'A11.284.180.610', 'A11.671.501.145.500'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activity patterns in human motion-sensitive areas depend on the interpretation of global motion. | Numerous imaging studies have contributed to the localization of motion-sensitive areas in the human brain. It is, however, still unclear how these areas contribute to global motion perception. Here, we investigate with functional MRI whether the motion-sensitive area hMT+/V5 is involved in perceptual segmentation and ... | ['Brain', 'Humans', 'Magnetic Resonance Imaging', 'Motion Perception', 'Pattern Recognition, Visual', 'Photic Stimulation', 'Time Factors'] | 12,368,476 | [['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['F02.463.593.932.567'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.723.729'], ['G01.910.857']] | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of sevoflurane on the release of [3H]dopamine from rat brain cortical slices. | Dopamine is a neurotransmitter that exerts major control on important brain functions and some lines of studies suggest that dopaminergic neurotransmission may be a potential target for volatile anesthetics. In the present study, rat brain cortical slices were labeled with [(3)H]dopamine to investigate the effects of s... | ['Adrenergic Uptake Inhibitors', 'Animals', 'Cerebral Cortex', 'Chelating Agents', 'Dopamine', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Enzyme Inhibitors', 'Female', 'In Vitro Techniques', 'Male', 'Methyl Ethers', 'Platelet Aggregation Inhibitors', 'Rats', 'Rats, Wistar', 'Reserpine', 'Sevoflurane', 'S... | 17,452,291 | [['D27.505.519.562.437.050', 'D27.505.519.625.050.601', 'D27.505.519.625.600.050', 'D27.505.696.577.050.601', 'D27.505.696.577.600.050'], ['B01.050'], ['A08.186.211.200.885.287.500'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['G07.690... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of nosocomial Serratia marcescens isolates: comparison of Fourier-transform infrared spectroscopy with pulsed-field gel electrophoresis of genomic DNA fragments and multilocus enzyme electrophoresis. | A total of 66 Serratia marcescens isolates from 46 patients was investigated by macrorestriction using XbaI followed by pulsed-field gel electrophoresis. 7 restriction fragment patterns attributable to more than one patient and 9 individual patterns were identified. The isolates were additionally characterized by multi... | ['Cross Infection', 'Electrophoresis', 'Electrophoresis, Gel, Pulsed-Field', 'Serratia marcescens', 'Spectroscopy, Fourier Transform Infrared'] | 10,467,658 | [['C01.248', 'C23.550.291.875.500'], ['E05.196.401', 'E05.301.300'], ['E05.196.401.220', 'E05.301.300.220'], ['B03.440.450.425.814.664', 'B03.660.250.150.720.500'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tafluprost protects rat retinal ganglion cells from apoptosis in vitro and in vivo. | BACKGROUND: To investigate whether tafluprost, which is a prostaglandin-related compound and an anti-glaucoma drug, has a direct anti-apoptotic effect in cultured retinal ganglion cells (RGCs) and rat RGCs in retinas with optic nerve crush (ONC).METHODS: RGC-5 cells were induced to undergo apoptosis by a serum deprivat... | ['Animals', 'Apoptosis', 'Calcium', 'Calcium Channel Blockers', 'Carbazoles', 'Caspase 3', 'Cell Line', 'Cell Survival', 'Culture Media, Serum-Free', 'Cyclic GMP-Dependent Protein Kinases', 'Dose-Response Relationship, Drug', 'Glutamic Acid', 'In Vitro Techniques', 'Instillation, Drug', 'Intracellular Membranes', 'Intr... | 19,551,401 | [['B01.050'], ['G04.146.954.035'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D03.633.100.473.144', 'D03.633.300.148'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enzymatic recovery and purification of polyhydroxybutyrate produced by Ralstonia eutropha. | Polyhydroxybutyrate (PHB) is the most studied among a wide variety of polyhydroxyalkanoates, bacterial biodegradable polymers known as potential substitutes for conventional plastics. This work aimed at evaluating the use of enzymes to recover and purify the PHB produced by Ralstonia eutropha DSM545. Screening experime... | ['Cellulase', 'Culture Media', 'Cupriavidus necator', 'Cysteine Endopeptidases', 'Enzymes', 'Evaluation Studies as Topic', 'Hydroxybutyrates', 'Muramidase', 'Polyesters', 'Time Factors'] | 16,253,372 | [['D08.811.277.450.420.200.200'], ['D27.720.470.305', 'E07.206'], ['B03.440.400.425.251.200.200', 'B03.660.075.090.688.200.200'], ['D08.811.277.656.262.500', 'D08.811.277.656.300.200'], ['D08.811'], ['E05.337', 'N05.715.360.335'], ['D02.241.081.114.937', 'D02.241.511.429', 'D10.251.400.143.781'], ['D08.811.277.450.642'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Selective attention as tuning: the case of stroke weight. | It has long been demonstrated that when grouping occurs, attention transfer between grouped elements is facilitated, as compared with attention transfer between elements-similarly distant-that are not grouped. This has been shown for grouping by connectedness, by orientation, and by color. The present article extends t... | ['Attention', 'Cues', 'Female', 'Humans', 'Male', 'Reaction Time', 'Space Perception', 'Touch', 'Transfer, Psychology', 'Visual Perception'] | 16,773,894 | [['F02.830.104.214'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.463.593.778'], ['F02.830.816.850', 'G11.561.790.850'], ['F02.463.425.910'], ['F02.463.593.932']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reactive glia support and guide axon growth in the rat thalamus during the first postnatal week. A sharply timed transition from permissive to non-permissive stage. | The present study demonstrates a supportive and guiding effect of the reactive glia on the postlesional axon growth in vivo, and offers a model system to compare permissive and non-permissive forms of the glial reaction. After stab wounds in early postnatal (P2-P9) rats, the reactive glia and the nerve fibers were dete... | ['Aging', 'Animals', 'Animals, Newborn', 'Brain Injuries', 'Cell Communication', 'Cell Differentiation', 'Denervation', 'Glial Fibrillary Acidic Protein', 'Gliosis', 'Growth Cones', 'Immunohistochemistry', 'Microscopy, Electron', 'Nerve Regeneration', 'Neurofilament Proteins', 'Neuroglia', 'Neuronal Plasticity', 'Rats'... | 11,600,320 | [['G07.345.124'], ['B01.050'], ['B01.050.050.282'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['G04.085'], ['G04.152'], ['E04.525.210'], ['D05.750.078.593.400', 'D12.776.220.475.400'], ['C23.550.369'], ['A11.284.180.075.249', 'A11.284.180.225.340', 'A11.284.180.610.345', 'A11.671.137.340', 'A11.671.240... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification and characterization of BpH2, a novel histone H1 homolog in Bordetella pertussis. | A basic protein, BpH2, with an apparent molecular mass of 18 kDa was purified from Bordetella pertussis, and the corresponding gene, bph2, was cloned. Sequence analysis revealed some homology to the H1 class of eukaryotic histones and to AlgP protein of Pseudomonas aeruginosa. BpH2 binds both single- and double-strande... | ['Adenylate Cyclase Toxin', 'Adhesins, Bacterial', 'Amino Acid Sequence', 'Bacterial Proteins', 'Base Sequence', 'Bordetella pertussis', 'DNA', 'DNA-Binding Proteins', 'Hemagglutinins', 'Histones', 'Molecular Sequence Data', 'Protein Precursors', 'Virulence Factors, Bordetella'] | 8,655,481 | [['D08.811.520.650.200.040', 'D23.946.123.946.040', 'D23.946.896.980.040'], ['D12.776.097.120.050', 'D12.776.543.100.050', 'D23.050.161.050'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B03.440.400.425.115.425.600', 'B03.660.075.090.344.425.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Electrophysiologic effects of magnesium chloride on the Purkinje fibers of the dog]. | In order to relate the cardiac antiarrhytmic properties of magnesium chloride (MgCl2) to its electrophysiological effects, a comparison of its actions on three different models of automaticity of the isolated Purkinje fibers of the dog, has been carried out. The spontaneous activity of the Purkinje fibers perfused with... | ['Animals', 'Anti-Arrhythmia Agents', 'Barium', 'Barium Compounds', 'Chlorides', 'Depression, Chemical', 'Dogs', 'Electrophysiology', 'Epinephrine', 'Female', 'Heart Conduction System', 'Heart Rate', 'Magnesium', 'Magnesium Chloride', 'Male', 'Membrane Potentials', 'Purkinje Fibers'] | 7,159,126 | [['B01.050'], ['D27.505.954.411.097'], ['D01.268.552.050', 'D01.268.556.062', 'D01.552.539.124', 'D01.552.544.062'], ['D01.103'], ['D01.210.450.150', 'D01.248.497.158.215'], ['G07.690.773.750'], ['B01.050.150.900.649.313.750.250.216.200'], ['H01.158.344.528', 'H01.158.782.236'], ['D02.033.100.291.310', 'D02.092.063.291... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Cardiovascular monkey telemetry: sensitivity to detect QT interval prolongation. | INTRODUCTION: Preclinical evaluation of delayed ventricular repolarization manifests electrocardiographically as QT interval prolongation and is routinely used as an indicator of potential risk for pro-arrhythmia (potential to cause Torsades de Pointes) of novel human pharmaceuticals. In accordance with ICH S7A and S7B... | ['Algorithms', 'Animals', 'Anti-Infective Agents', 'Aza Compounds', 'Blood Pressure', 'Dose-Response Relationship, Drug', 'Electrocardiography', 'Electrodes, Implanted', 'Excipients', 'Fluoroquinolones', 'Heart Rate', 'Hemodynamics', 'Long QT Syndrome', 'Macaca mulatta', 'Male', 'Methylcellulose', 'Moxifloxacin', 'Quin... | 16,679,034 | [['G17.035', 'L01.224.050'], ['B01.050'], ['D27.505.954.122'], ['D02.145'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E07.305.250.319', 'E07.695.202'], ['D26.650.700.419', 'D27.720.744.770.419'], ['D03.633.100.810.835.322'], ['E01.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Hydrophytes lack potential to exhibit cadmium stress induced enhancement in lipid peroxidation and accumulation of proline. | Investigations were carried out to evaluate if hydrophytes (viz. Ceratophyllum, Wolffia, and Hydrilla) can be used as markers to assess the level of heavy metal pollution in aquatic bodies. The potential of these hydrophytes for lipid peroxidation and accumulation of proline in response to cadmium (Cd2+) pollution was ... | ['Cadmium', 'Fresh Water', 'India', 'Lipid Peroxidation', 'Magnoliopsida', 'Malondialdehyde', 'Proline', 'Water Pollution, Chemical'] | 15,036,869 | [['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['G16.500.275.280', 'N06.230.232'], ['Z01.252.245.393'], ['G02.111.515', 'G03.295.531.587'], ['B01.650.940.800.575.912.250'], ['D02.047.700'], ['D12.125.072.401.623'], ['N06.850.460.790.410']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Cyclic AMP- and phorbol ester-regulated Cl- permeabilities in primary cultures of human and rabbit colonocytes. | Chloride transport in 24-h primary cultures of human and rabbit distal colonic crypt cells (90 +/- 5% viable) were characterized using the Cl(-)-sensitive fluorescent probe 6-methoxyquinolyl acetoethyl ester. To calculate the Cl- influx in millimolar per second, the Stern-Volmer quenching constant was determined to be ... | ['8-Bromo Cyclic Adenosine Monophosphate', 'Alprostadil', 'Animals', 'Biological Transport', 'Bumetanide', 'Carrier Proteins', 'Cell Membrane Permeability', 'Cell Separation', 'Cells, Cultured', 'Chlorides', 'Colforsin', 'Colon', 'Cyclic AMP', 'Fluorescent Dyes', 'Furosemide', 'Humans', 'Indomethacin', 'Kinetics', 'Pho... | 8,203,530 | [['D03.633.100.759.646.138.395.225', 'D13.695.462.200.225', 'D13.695.667.138.395.225', 'D13.695.827.068.395.225'], ['D10.251.355.255.550.250.100', 'D10.251.355.325.050', 'D23.469.050.175.725.250.100'], ['B01.050'], ['G03.143'], ['D02.065.884.150', 'D02.241.223.100.050.300.200', 'D02.455.426.559.389.127.020.452.500', 'D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The evaluation of imprecision in collaborative immunoassay quality-assessment programmes. | The calculation of within-laboratory imprecision in quality-assessment (QA) programmes normally involves combining data from different analyte concentrations to calculate an average standard deviation (SD) or coefficient of variation. However, for immunoassay neither of these parameters is concentration independent. Th... | ['Humans', 'Immunoassay', 'Laboratories', 'Quality Control', 'Reagent Kits, Diagnostic', 'Thyroxine', 'Triiodothyronine'] | 6,517,490 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['J03.520', 'N02.278.487'], ['J01.897.608'], ['D27.505.259.875', 'D27.720.470.410.680', 'E07.720'], ['D06.472.931.812', 'D12.125.072.050.767'], ['D06.472.931.740.385', 'D12.125.072.050.767.741.894']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Low-density granulocytes and monocytes as biomarkers of cardiovascular risk in systemic lupus erythematosus. | OBJECTIVE: The aim was to evaluate the most relevant cell populations involved in vascular homeostasis as potential biomarkers of SLE-related cardiovascular disease (CVD).METHODS: Low-density granulocytes (LDGs), monocyte subsets, endothelial progenitor cells, angiogenic T (Tang) cells, CD4+CD28null and Th1/Th17 lympho... | ['Adult', 'Biomarkers', 'Cardiovascular Diseases', 'Case-Control Studies', 'Cytokines', 'Female', 'Granulocytes', 'Humans', 'Lupus Erythematosus, Systemic', 'Male', 'Middle Aged', 'Monocytes'] | 32,031,658 | [['M01.060.116'], ['D23.101'], ['C14'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A11.118.637.415', 'A11.148.350', 'A11.627.340', 'A15.145.229.637.415', 'A15.378.316.340', 'A15.382.490.315'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells. | Nitric Oxide (NO•) is a small radical, which mediates multiple important cellular functions in mammals, bacteria and plants. Despite the existence of a large number of methods for detecting NO• in vivo and in vitro, the real-time monitoring of NO• at the single-cell level is very challenging. The physiological or patho... | ['Animals', 'Cells, Cultured', 'Endothelial Cells', 'Fluorescent Dyes', 'Fura-2', 'Genetic Vectors', 'HEK293 Cells', 'Humans', 'Hydrazines', 'Microscopy, Fluorescence', 'Nitric Oxide', 'Nitric Oxide Donors', 'Nitroprusside', 'Parvovirinae'] | 28,362,417 | [['B01.050'], ['A11.251'], ['A11.436.275'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D03.383.129.462.285', 'D03.633.100.127.250'], ['G05.360.337'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.442'], ['E01.370.350.515.458', 'E05.595.458'], ['D01.339.387', 'D01.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A head above the rest: height and adolescent psychological well-being. | Using data from the National Longitudinal Study of Adolescent Health, we examine the effect of adolescent height on mental health as measured by Center for Epidemiological Studies Depression (CES-D) scores and Rosenberg Self-Esteem (RSE) scores. We find evidence that height is associated with fewer symptoms of depressi... | ['Adolescent', 'Body Height', 'Body Mass Index', 'Child', 'Depression', 'Educational Status', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Mental Health', 'Psychology, Adolescent', 'Self Concept', 'United States', 'Young Adult'] | 19,447,690 | [['M01.060.057'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406'], ['F01.145.126.350'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Electrochemical DNA hybridization sensors based on conducting polymers. | Conducting polymers (CPs) are a group of polymeric materials that have attracted considerable attention because of their unique electronic, chemical, and biochemical properties. This is reflected in their use in a wide range of potential applications, including light-emitting diodes, anti-static coating, electrochromic... | ['Biosensing Techniques', 'DNA', 'Electrochemistry', 'Humans', 'Nucleic Acid Hybridization', 'Polymers'] | 25,664,436 | [['E05.601.043'], ['D13.444.308'], ['H01.181.529.307'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.661', 'G02.111.611'], ['D05.750', 'D25.720', 'J01.637.051.720']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Structure of chicken calcitonin predicted by partial nucleotide sequence of its precursor. | DNA complementary to chicken ultimobranchial gland mRNA was cloned into the Pst I site of plasmid vector pBR322. A plasmid was selected by DNA-mRNA hybridization. We report here the partial nucleotide sequence of chicken calcitonin mRNA and the deduced complete amino acid sequence of chicken calcitonin. | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Calcitonin', 'Centrifugation, Density Gradient', 'Cloning, Molecular', 'DNA', 'Plasmids', 'Protein Precursors', 'RNA, Messenger'] | 3,838,160 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D06.472.699.150', 'D06.472.931.052', 'D12.644.400.095', 'D12.644.548.150', 'D12.776.631.650.095'], ['E05.181.724.336', 'E05.196.941.336'], ['E05.393.220'], ['D13.444.308'], ['G05.360.600'], ['D12.776.8... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Special plant species determines diet breadth of phytophagous insects: a study on host plant expansion of the host-specialized Aphis gossypii Glover. | Host specialization is a ubiquitous character of phytophagous insects. The polyphagous population is usually composed of some subpopulations that can use only a few closely related plants. Cotton-melon aphids, Aphis gossypii Glover exhibited strong host specialization, and the cotton- and cucurbits-specialized biotypes... | ['Animals', 'Aphids', 'Cucumis sativus', 'Diet', 'Ecosystem', 'Gossypium', 'Herbivory', 'Host Specificity', 'Plants', 'Population Dynamics'] | 23,580,128 | [['B01.050'], ['B01.050.500.131.617.412.165'], ['B01.650.940.800.575.912.250.300.188.666'], ['G07.203.650.240'], ['G16.500.275.157', 'N06.230.124'], ['B01.650.940.800.575.912.250.859.821.500.244'], ['F01.145.113.547.600', 'F01.145.407.758', 'G07.203.650.353.758'], ['G06.462.380', 'G16.527.200.380'], ['B01.650'], ['I01.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
A new centrally acting antihypertensive (ICI 106270) which separates antihypertensive effects from sedation. | 1. 6-(2-Chloro-6-fluorophenyl)-2,3,6,7-tetrahydro-5H-pyrrolo-[1,2-a]-imidazole hydrobromide (ICI 106270) has been developed with the objective of achieving satisfactory blood pressure (BP) reduction while minimising the side-effects seen with clonidine. 2. In the pentobarbitone sodium anaesthetised rat the dose of ICI ... | ['Anesthesia', 'Animals', 'Antihypertensive Agents', 'Blood Pressure', 'Clonidine', 'Female', 'Heart Rate', 'Hypertension, Renal', 'Imidazoles', 'Motor Activity', 'Pentobarbital', 'Rats', 'Sleep', 'Sympathetic Nervous System'] | 7,198,445 | [['E03.155'], ['B01.050'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D03.383.129.308.436.500'], ['E01.370.600.875.500', 'G09.330.380.500'], ['C12.777.419.331', 'C13.351.968.419.331', 'C14.907.489.631'], ['D03.383.129.308'], ['F01.145.632', 'G11.427.410.698'], ['D03.383.742.698.253.593'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cost-effectiveness of renal denervation therapy for the treatment of resistant hypertension in The Netherlands. | OBJECTIVES: Safety and efficacy data for catheter-based renal denervation (RDN) in the treatment of resistant hypertension have been used to estimate the cost-effectiveness of this approach. However, there are no Dutch-specific analyses. This study examined the cost-effectiveness of RDN from the perspective of the heal... | ['Aged', 'Cost-Benefit Analysis', 'Denervation', 'Female', 'Humans', 'Hypertension', 'Kidney', 'Male', 'Markov Chains', 'Middle Aged', 'Models, Econometric', 'Netherlands', 'Quality-Adjusted Life Years'] | 25,367,314 | [['M01.060.116.100'], ['N03.219.151.125'], ['E04.525.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['A05.810.453'], ['E05.318.740.600.500', 'E05.318.740.996.500', 'G17.830.500', 'N05.715.360.750.625.500', 'N05.715.360.750.770.500', 'N06.850.520.830.600.500', 'N06.850.520.830.996.500'], ['M01.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mycoplasma pneumonia: failure of erythromycin therapy. | Two cases of mycoplasma pneumonia are described which failed to respond to prolonged treatment with erythromycin. The substitution of oxytetracycline therapy resulted in rapid clinical and radiological resolution. | ['Adult', 'Erythromycin', 'Female', 'Humans', 'Male', 'Oxytetracycline', 'Pneumonia, Mycoplasma'] | 7,455,669 | [['M01.060.116'], ['D02.540.576.500.992'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.847.562.900.600', 'D04.615.562.900.600'], ['C01.150.252.400.610.610.760', 'C01.150.252.620.500', 'C01.748.610.540.545', 'C08.381.677.540.500', 'C08.730.610.540.545']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Radiation for bone metastases in Ewing sarcoma and rhabdomyosarcoma. | BACKGROUND: The role, optimal dose, and efficacy of radiotherapy (RT) for the treatment of bone metastases in rhabdomyosarcoma (RMS) and Ewing sarcoma (ES) are unclear.PROCEDURE: All patients with ES or RMS who received RT for bone metastases with curative intent during frontline therapy at Memorial Sloan Kettering Can... | ['Adolescent', 'Adult', 'Antineoplastic Combined Chemotherapy Protocols', 'Bone Neoplasms', 'Child', 'Child, Preschool', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Infant', 'Male', 'Neoplasm Metastasis', 'Retrospective Studies', 'Rhabdomyosarcoma', 'Sarcoma, Ewing'] | 25,346,208 | [['M01.060.057'], ['M01.060.116'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.149', 'C05.116.231'], ['M01.060.406'], ['M01.060.406.448'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04.697.650', 'C23.550.727.650'], ['E05.318.372.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Maternal diet and risk of astrocytic glioma in children: a report from the Childrens Cancer Group (United States and Canada) | N-nitroso compounds and their precursors, nitrites and nitrates, have been hypothesized as risk factors, and vitamins C and E, which inhibit N-nitroso formation, as protective factors for brain tumors. A case-control study of maternal diet during pregnancy and risk of astrocytoma, the most common childhood brain tumor,... | ['Astrocytoma', 'Brain Neoplasms', 'Canada', 'Carotenoids', 'Child, Preschool', 'Diet', 'Female', 'Humans', 'Income', 'Iron', 'Meat', 'Neuroectodermal Tumors, Primitive', 'Nitroso Compounds', 'Pregnancy', 'Risk Factors', 'United States', 'Vitamin A', 'Vitamin E', 'beta Carotene'] | 8,167,265 | [['C04.557.465.625.600.380.080', 'C04.557.470.670.380.080', 'C04.557.580.625.600.380.080'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['Z01.107.567.176'], ['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['M01.060.406.448'], ['G07.203.650.240'], ['B0... | ['Diseases [C]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Cellular telephone communication between hospitals and ambulances. | Cellular telephones provide a new means of wireless telephone communication. In an experimental design study comparing the clarity of receiving and transmitting communications with cellular telephones versus conventional emergency medical radio/microwave equipment, cellular telephones proved to be superior in all aspec... | ['Ambulances', 'Emergency Medical Service Communication Systems', 'Emergency Medical Services', 'Hospitals', 'Humans', 'Microwaves', 'Radio', 'Telephone'] | 3,334,797 | [['J01.937.500.050', 'N02.421.297.879.100'], ['N02.421.297.058'], ['N02.421.297'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['J01.897.280.500.739', 'L01.178.590.700', 'L01.178.820.090.739', 'L01.178.847.514'], ['L01.178.... | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Alkali-templated surface nanopatterning of chalcogenide thin films: a novel approach toward solar cells with enhanced efficiency. | Concepts of localized contacts and junctions through surface passivation layers are already advantageously applied in Si wafer-based photovoltaic technologies. For Cu(In,Ga)Se2 thin film solar cells, such concepts are generally not applied, especially at the heterojunction, because of the lack of a simple method yieldi... | ['Alkalies', 'Nanostructures', 'Solar Energy', 'Sunlight', 'Water'] | 25,844,923 | [['D01.045'], ['J01.637.512'], ['G01.750.897', 'N06.230.132.644.500'], ['G01.358.500.505.650.836', 'G01.750.250.650.836', 'G01.750.770.578.836', 'G16.500.275.063.725.525', 'G16.500.750.775.525', 'N06.230.300.100.725.525'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Diet-induced regulation of bitter taste receptor subtypes in the mouse gastrointestinal tract. | Bitter taste receptors and signaling molecules, which detect bitter taste in the mouth, are expressed in the gut mucosa. In this study, we tested whether two distinct bitter taste receptors, the bitter taste receptor 138 (T2R138), selectively activated by isothiocyanates, and the broadly tuned bitter taste receptor 108... | ['Animals', 'Colon', 'Diet', 'Diet, High-Fat', 'Duodenum', 'Fasting', 'Gastric Mucosa', 'Gastrointestinal Tract', 'Gene Expression Regulation', 'Heterotrimeric GTP-Binding Proteins', 'Ileum', 'Intestine, Small', 'Jejunum', 'Male', 'Mice', 'Mice, Inbred C57BL', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'R... | 25,238,152 | [['B01.050'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['G07.203.650.240'], ['G07.203.650.240.267'], ['A03.556.124.684.124', 'A03.556.875.249'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['A03.556.875.875.440', 'A10.615.550.291'], ['A03.556'], ['G05.308'], ['D08.811.277.040.330.300.200',... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of quinolone residues in tilapias (Orechromis niloticus) by HPLC-FLD and LC-MS/MS QToF. | A method for the simultaneous determination of flumequine, oxolinic acid, sarafloxacin, danofloxacin, enrofloxacin, and ciprofloxacin in tilapia (Orechromis niloticus) fillet, using high-performance liquid chromatography with fluorescence detection (HPLC-FLD) is presented. The quinolones were extracted from the food ma... | ['Animals', 'Anti-Bacterial Agents', 'Chromatography, High Pressure Liquid', 'Chromatography, Liquid', 'Drug Residues', 'Fluorescence', 'Fluoroquinolones', 'Food Analysis', 'Tandem Mass Spectrometry', 'Tilapia'] | 21,462,582 | [['B01.050'], ['D27.505.954.122.085'], ['E05.196.181.400.300'], ['E05.196.181.400'], ['N06.850.460.200.250'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['D03.633.100.810.835.322'], ['E05.362', 'J01.576.423.850.100'], ['E05.196.566.880'], ['B01.050.150.900.493.602.200.800']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Patterning of cell-instructive hydrogels by hydrodynamic flow focusing. | Microfluidic gradient systems offer a very precise means to probe the response of cells to graded biomolecular signals in vitro, for example to model how morphogen proteins affect cell fate during developmental processes. However, existing gradient makers are designed for non-physiological plastic or glass cell culture... | ['Animals', 'Cells, Cultured', 'Embryonic Stem Cells', 'Hydrodynamics', 'Hydrogels', 'Mice', 'Microfluidic Analytical Techniques', 'Polyethylene Glycols', 'Protein Engineering', 'Software', 'Surface Properties'] | 23,598,796 | [['B01.050'], ['A11.251'], ['A11.872.700.250'], ['G01.342'], ['D20.280.320.375', 'D26.255.165.320.375'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.588.465'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['E05.393.420.601'], ['L01.224.900'], ['G02.860']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Mitotic activity in the blastema and stump tissues of regenerating hind limbs of Xenopus laevis larvae after amputation at ankle level. An autoradiographic study. | Mitotic activity, as indicated by DNA synthesis, was studied by autoradiographic analysis along the proximodistal axis of regenerating limbs in the early and later larval stages 53 and 57 of Xenopus laevis. Wound-healing, dedifferentiation, blastema formation and growth phases were studied. Most of the various stump ti... | ['Amputation Stumps', 'Animals', 'Autoradiography', 'Hindlimb', 'Mitosis', 'Regeneration', 'Tarsus, Animal', 'Xenopus laevis'] | 2,341,072 | [['A01.378.100'], ['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['A13.473'], ['G04.144.220.220.781', 'G05.113.220.781'], ['G16.762'], ['A13.473.821'], ['B01.050.150.900.090.180.610.500.562']] | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modeling pulmonary kinetics of 2-deoxy-2-[18F]fluoro-D-glucose during acute lung injury. | RATIONALE AND OBJECTIVES: Dynamic positron emission tomographic imaging of the radiotracer 2-deoxy-2-[(18)F]fluoro-D-glucose ((18)F-FDG) is increasingly used to assess metabolic activity of lung inflammatory cells. To analyze the kinetics of (18)F-FDG in brain and tumor tissues, the Sokoloff model has been typically us... | ['Analysis of Variance', 'Animals', 'Fluorodeoxyglucose F18', 'Models, Biological', 'Radionuclide Imaging', 'Radiopharmaceuticals', 'Respiratory Distress Syndrome', 'Sheep'] | 18,486,012 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D09.254.229.500'], ['E05.599.395'], ['E01.370.350.710', 'E01.370.384.730'], ['D27.505.259.843', 'D27.505.519.871', 'D27.720.470.410.650'], ['C08.381.840', 'C08.618.840'], ['B01.050.150.900.649.313.500.380.791']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Is dauer pheromone of Caenorhabditis elegans really a pheromone? | Animals respond to signals and cues in their environment. The difference between a signal (e.g. a pheromone) and a cue (e.g. a waste product) is that the information content of a signal is subject to natural selection, whereas that of a cue is not. The model free-living nematode Caenorhabditis elegans forms an alternat... | ['Animals', 'Caenorhabditis elegans', 'Larva', 'Pheromones', 'Signal Transduction'] | 15,034,661 | [['B01.050'], ['B01.050.500.500.294.400.875.660.250.250'], ['B05.500.500', 'G07.345.500.550.500.500'], ['D23.641'], ['G02.111.820', 'G04.835']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exfoliation material in different sections of the eye. | Nine trabeculectomy samples, five iridectomy samples and one lens of an exfoliation syndrom were examined. Next to typical exfoliation syndrome fibrils, the alteration of endothelial membranes and similar structures has been pointed out. Concerning the glaucoma genesis, it is being discussed whether a participation of ... | ['Basement Membrane', 'Endothelium', 'Eye', 'Glaucoma', 'Humans', 'Iris', 'Lens, Crystalline', 'Syndrome', 'Trabecular Meshwork'] | 303,469 | [['A10.272.220', 'A10.615.179'], ['A10.272.491'], ['A01.456.505.420', 'A09.371'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.060.450', 'A09.371.894.513'], ['A09.371.060.500'], ['C23.550.288.500'], ['A09.371.060.932']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of saliva: total plasma chloroquine levels relationship by high performance liquid chromatography. | The use of saliva chloroquine concentrations measurement as a noninvasive technique in the evaluation of the pharmacokinetics of the drug was investigated. Chloroquine concentrations in saliva and plasma were measured in eight healthy volunteers after a single oral dose of two tablets of chloroquine sulfate. The saliva... | ['Adult', 'Chloroquine', 'Chromatography, High Pressure Liquid', 'Clinical Trials as Topic', 'Female', 'Humans', 'Male', 'Saliva', 'Time Factors'] | 2,693,504 | [['M01.060.116'], ['D03.633.100.810.050.180'], ['E05.196.181.400.300'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.200.666'], ['G01.910.857']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ophthalmomyiasis externa: three cases caused by Oestrus ovis larvae in Turkey. | Ocular involvement of parasitic infections includes external, internal and orbital ophthalmomyiasis. Oestrus ovis (sheep botfly) is the most common cause of ophthalmomyiasis externa. Living in warm climates, particularly in agricultural districts, is a risk factor. Although external ophthalmomyiasis can be treated by r... | ['Adolescent', 'Adult', 'Animals', 'Diagnosis, Differential', 'Diptera', 'Eye Infections, Parasitic', 'Female', 'Humans', 'Larva', 'Male', 'Myiasis', 'Sheep', 'Turkey'] | 24,705,772 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['E01.171'], ['B01.050.500.131.617.720.500.500.750'], ['C01.610.300', 'C11.294.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B05.500.500', 'G07.345.500.550.500.500'], ['C01.610.858.211.503'], ['B01.050.150.900.649.313.500.380.791'], ['Z01.252.245.500.850']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
The Early Postoperative Effects of Cochlear Implantation on Horizontal Semicircular Canal Function. | OBJECTIVES: To use video head impulse testing to examine the effect of cochlear implantation (CI) on horizontal SCC vestibulo-ocular reflex (VOR) gain early after surgery, and to relate outcomes to subjective imbalance.STUDY DESIGN: Prospective cohort study.SETTING: Academic tertiary referral center.PATIENTS: Thirty-se... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cochlear Implantation', 'Cochlear Implants', 'Female', 'Head Impulse Test', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Postoperative Period', 'Postural Balance', 'Prospective Studies', 'Reflex, Vestibulo-Ocular', 'Semicircular Canals', 'Sensation Disorders',... | 29,995,005 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.580.450.220', 'E04.650.220'], ['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['E01.370.382.900.640'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E04.614.750'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification of the most sensitive and robust immunohistochemical markers in different categories of ovarian sex cord-stromal tumors. | Different immunohistochemical sex cord-stromal markers have been previously studied in various types of ovarian sex cord-stromal tumors; however, the sensitivity for sex cord-stromal lineage may vary between markers, and some markers may not be as sensitive in some types of sex cord-stromal tumors compared with other t... | ['Biomarkers, Tumor', 'Female', 'Humans', 'Immunohistochemistry', 'Ovarian Neoplasms', 'Sensitivity and Specificity', 'Sex Cord-Gonadal Stromal Tumors'] | 19,033,865 | [['D23.101.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['C04.588.322.455... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Adjacent segment stenosis after lumbar fusion requiring second operation. | BACKGROUND: Whereas degeneration of the segment adjacent to lumbar fusion has been often seen on radiographs, a small number of patients with such degenerative changes undergo reoperation. Most follow-up studies have focused on adjacent segment disease based on analysis of radiographs. The present study was conducted t... | ['Adult', 'Aged', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Reoperation', 'Spinal Fusion', 'Spinal Stenosis'] | 16,193,361 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.690'], ['E04.555.100.700'], ['C05.116.900.825']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Allogeneic Mesenchymal Stromal Cells Transplanted Onto the Heart Surface Achieve Therapeutic Myocardial Repair Despite Immunologic Responses in Rats. | BACKGROUND: Transplantation of allogeneic mesenchymal stromal cells (MSCs) is a promising treatment for heart failure. We have shown that epicardial placement of cell sheets markedly increases donor cell survival and augments therapeutic effects compared with the current methods. Although immune rejection of intramyoca... | ['Animals', 'CD4-Positive T-Lymphocytes', 'Cell Survival', 'Cells, Cultured', 'Disease Models, Animal', 'Graft Rejection', 'Graft Survival', 'Heart Failure', 'Interleukin-6', 'Male', 'Mesenchymal Stem Cell Transplantation', 'Mesenchymal Stem Cells', 'Myocardial Infarction', 'Myocardium', 'Rats, Inbred F344', 'Rats, Inb... | 26,896,478 | [['B01.050'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['G04.346'], ['A11.251'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G12.875.545.328'], ['G12.875.545.340'], ['C14.280.434'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
t10,c12-Conjugated linoleic acid stimulates mammary tumor progression in Her2/ErbB2 mice through activation of both proliferative and survival pathways. | The t10,c12 isomer of conjugated linoleic acid (CLA) inhibits rat mammary carcinogenesis, metastasis from a transplantable mouse mammary tumor and angiogenesis; however, it stimulates mammary tumorigenesis in transgenic mice overexpressing ErbB2 in the mammary epithelium (ErbB2 transgenic mice). In the current study, w... | ['Administration, Oral', 'Animals', 'Diet', 'Disease Progression', 'Female', 'Genes, erbB-2', 'Humans', 'Immunohistochemistry', 'Linoleic Acids, Conjugated', 'Mammary Glands, Animal', 'Mammary Neoplasms, Experimental', 'Mice', 'Mice, Transgenic'] | 18,339,686 | [['E02.319.267.100'], ['B01.050'], ['G07.203.650.240'], ['C23.550.291.656'], ['G05.360.340.024.340.375.500.791.295.305'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A four-CRD C-type lectin from razor clam Sinonovacula constricta mediates agglutination and phagocytosis. | C-type lectins are a superfamily of Ca2+-dependent carbohydrate-binding proteins that play crucial roles in invertebrate immunity. In this study, a novel C-type lectin gene (ScCTL-1) was identified in razor clam Sinonovacula constricta. The ScCTL-1 gene, consisting of four C-type carbohydrate recognition domains (CRDs)... | ['Agglutination', 'Amino Acid Sequence', 'Animals', 'Bivalvia', 'Carbohydrates', 'Hepatopancreas', 'Lectins, C-Type', 'Phagocytosis', 'Phylogeny', 'Protein Domains', 'Sequence Homology', 'Staphylococcal Infections', 'Staphylococcus aureus', 'Vibrio'] | 31,843,359 | [['G02.111.026', 'G12.122.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.500.644.080'], ['D09'], ['A13.463'], ['D12.776.503.280'], ['G04.417.350', 'G09.188.665', 'G12.450.564.809', 'G12.688'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G02.111.570.820.709.275.750', 'G02.111.570.820.709.610.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Evaluation of tRNA gene PCR for identification of mollicutes. | We evaluated the applicability of tRNA gene PCR in combination with fluorescent capillary electrophoresis with an ABI310 genetic analyzer (Applied Biosystems, Calif.) for the identification of different mollicute species. A total of 103 strains and DNA extracts of 30 different species belonging to the genera Acholeplas... | ['Acholeplasma', 'Animals', 'Animals, Domestic', 'Bacterial Typing Techniques', 'Birds', 'Cattle', 'DNA, Bacterial', 'Genes, rRNA', 'Humans', 'Mice', 'Molecular Sequence Data', 'Mycoplasma', 'Polymerase Chain Reaction', 'RNA, Ribosomal, 16S', 'RNA, Transfer', 'Tenericutes', 'Ureaplasma'] | 16,145,107 | [['B03.440.860.074.150'], ['B01.050'], ['B01.050.050.116'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['B01.050.150.900.248'], ['B01.050.150.900.649.313.500.380.271'], ['D13.444.308.212'], ['G05.360.340.024.340.645.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.5... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Sequence analysis of the spliced-leader intergenic region (SL-IR) and random amplified polymorphic DNA (RAPD) of Trypanosoma rangeli strains isolated from Rhodnius ecuadoriensis, R. colombiensis, R. pallescens and R. prolixus suggests a degree of co-evolution between parasites and vectors. | Spliced leader intergenic region (SL-IR) sequences from 23 Trypanosoma rangeli strains isolated from the salivary glands of Rhodnius colombiensis, R. ecuadoriensis, R. pallescens and R. prolixus and two human strains revealed the existence of 4 genotypes with CA, GT, TA, ATT and GTAT microsatellite repeats and the pres... | ['Animals', 'Biological Evolution', 'DNA, Intergenic', 'DNA, Protozoan', 'Evolution, Molecular', 'Genetic Variation', 'Genome, Protozoan', 'Genotype', 'Host-Parasite Interactions', 'Humans', 'Insect Vectors', 'Phylogeny', 'RNA, Spliced Leader', 'Random Amplified Polymorphic DNA Technique', 'Rhodnius', 'Sequence Analysi... | 21,718,675 | [['B01.050'], ['G05.045', 'G16.075'], ['D13.444.308.324', 'G05.360.340.024.220'], ['D13.444.308.442'], ['G05.045.250', 'G16.075.250'], ['G05.365'], ['G05.360.340.397'], ['G05.380'], ['G16.527.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['G05.69... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
A Phase II trial of weekly bortezomib and dexamethasone in veterans with newly diagnosed multiple myeloma not eligible for or who deferred autologous stem cell transplantation. | Once-weekly administration of bortezomib has reduced bortezomib-induced peripheral neuropathy without affecting response rates, but this has only been demonstrated prospectively in three- and four- drug combinations. We report a phase II trial of alternate dosing and schedule of bortezomib and dexamethasone in newly di... | ['Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Autografts', 'Boronic Acids', 'Bortezomib', 'Dexamethasone', 'Disease-Free Survival', 'Female', 'Humans', 'Male', 'Middle Aged', 'Multiple Myeloma', 'Pyrazines', 'Stem Cell Transplantation', 'Survival Rate', 'Veterans'] | 25,572,917 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['A01.941.750'], ['D01.029.260.110', 'D01.132.285', 'D02.203.200'], ['D01.029.260.110.500', 'D01.132.285.500', 'D02.203.200.500', 'D03.383.679.450'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['E01.78... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evolutionary relationships among genes for antibiotic resistance. | The genes that determine resistance to antibiotics are commonly found encoded by extrachromosomal elements in bacteria. These were described first in Enterobacteriaceae and subsequently in a variety of other genera; their spread is associated with the increased use of antibiotics in human and animal medicine. Antibioti... | ['Amino Acid Sequence', 'Aminoglycosides', 'Anti-Bacterial Agents', 'Bacteria', 'Biological Evolution', 'Drug Resistance, Microbial', 'Genes, Bacterial', 'Plasmids'] | 6,559,117 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D09.408.051'], ['D27.505.954.122.085'], ['B03'], ['G05.045', 'G16.075'], ['G06.225', 'G07.690.773.984.269'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.360.600']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Evidence that functional glutamate receptors are not expressed on rat or human cerebromicrovascular endothelial cells. | Excitatory amino acids can modify the tone of cerebral vessels and permeability of the blood-brain barrier (BBB) by acting directly on endothelial cells of cerebral vessels or indirectly by activating receptors expressed on other brain cells. In this study we examined whether rat or human cerebromicrovascular endotheli... | ['Animals', 'Brain Ischemia', 'Calcium', 'Capillaries', 'Cattle', 'Cells, Cultured', 'Cerebrovascular Circulation', 'Colforsin', 'Cyclic AMP', 'Cycloleucine', 'Endothelin-1', 'Endothelium, Vascular', 'Gene Expression', 'Humans', 'Inositol 1,4,5-Trisphosphate', 'Kainic Acid', 'Mice', 'N-Methylaspartate', 'Neurons', 'Pol... | 9,538,905 | [['B01.050'], ['C10.228.140.300.150', 'C14.907.253.092'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A07.015.461.165'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['G09.330.100.159'], ['D02.455.849.291.300'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Changes in nurse-midwifery practices in Taiwan]. | Nurse-midwifery professionals play an important role for pregnant women in the healthcare system, providing assistance to both expectant women and their newborn children. In Taiwan, midwifery professionals have contributed significantly to women and infant health. Before 1960s, nurse-midwives were the main nursing care... | ['Education, Nursing', 'Female', 'Humans', 'Midwifery', 'Taiwan'] | 19,319,807 | [['I02.358.462'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.478.676.416'], ['Z01.252.474.872', 'Z01.639.850']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 |
High autophagy in the naked mole rat may play a significant role in maintaining good health. | BACKGROUND/AIMS: The maximum lifespan of the naked mole rat is over 28.3 years, which exceeds that of any other rodent species, suggesting that age-related changes in its body composition and functionality are either attenuated or delayed in this extraordinarily long-lived species. However, the mechanisms underlying th... | ['Adenine', 'Animals', 'Apoptosis Regulatory Proteins', 'Autophagy', 'Hepatic Stellate Cells', 'Immunosuppressive Agents', 'Longevity', 'Mice', 'Microtubule-Associated Proteins', 'Mole Rats', 'Sirolimus'] | 24,525,846 | [['D03.633.100.759.138'], ['B01.050'], ['D12.644.360.075', 'D12.776.476.075'], ['G04.011'], ['A11.561'], ['D27.505.696.477.656'], ['G07.345.124.519', 'G07.540'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.220.600.450', 'D12.776.631.560'], ['B01.050.150.900.649.313.992.600'], ['D02.540.505.760']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dietary changes reported by a random sample of elderly people. | A random sub-sample of 153 elderly people was followed up 18 months after a large-scale random dietary survey of adults aged 65 years and over residing in Adelaide, South Australia. The follow-up questionnaire examined self-reported dietary and weight change over the 18 month period since the original study. The same s... | ['Aged', 'Diet Surveys', 'Feeding Behavior', 'Female', 'Humans', 'Male', 'South Australia'] | 1,296,986 | [['M01.060.116.100'], ['E05.318.308.980.485.350', 'N05.715.360.300.800.469.300', 'N06.850.505.616.300', 'N06.850.520.308.980.469.350'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.639.100.968', 'Z01.678.100.373.968']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Long non-coding RNA MEG3 inhibits chondrogenic differentiation of synovium-derived mesenchymal stem cells by epigenetically inhibiting TRIB2 via methyltransferase EZH2. | Osteoarthritis (OA) is a highly prevalent skeletal disease. Mesenchymal stem cell-derived cartilage tissue engineering is a clinical method used for OA treatment. Investigations on the molecular regulatory mechanisms of the chondrogenic differentiation of synovium-derived mesenchymal stem cells(SMSCs) will help promote... | ['Calcium-Calmodulin-Dependent Protein Kinases', 'Cell Differentiation', 'Cells, Cultured', 'Chondrogenesis', 'Enhancer of Zeste Homolog 2 Protein', 'Humans', 'Mesenchymal Stem Cells', 'RNA, Long Noncoding', 'Synovial Membrane'] | 31,376,524 | [['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['G04.152'], ['A11.251'], ['G07.345.500.325.377.625.180', 'G11.427.578.180'], ['D05.500.781.750.250', 'D08.811.913.555.500.800.200.500.500.500', 'D12.776.660.235.600.200.250', 'D12.776.664.235.800.200.250', 'D12.776.930.780.890.200.250'], ['B01... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Schizophrenic disorder and social functioning. | Social functioning is assessed according to 84 questioned subjects with schizophrenic disorder and their 84 key figures. Schizophrenic subjects showed significant dysfunction in all reviewed areas of behaviour and social roles. Key figures of all schizophrenic subjects most often showed a positive attitude in regard to... | ['Adult', 'Caregivers', 'Cost of Illness', 'Family Relations', 'Female', 'Humans', 'Male', 'Personality Assessment', 'Psychiatric Status Rating Scales', 'Schizophrenia', 'Schizophrenic Psychology', 'Social Adjustment', 'Social Behavior Disorders', 'Social Support'] | 9,682,929 | [['M01.060.116'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['F01.829.263.370', 'I01.880.853.150.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.513'], ['F04.711.513.653'], ['F03.700.750'], ['F04.824'], ['F01.1... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Outcomes and prognostic factors for aggressive posterior retinopathy of prematurity following initial treatment with intravitreal ranibizumab. | BACKGROUND: This study sought to identify factors associated with retinal detachment and retreatment of aggressive posterior retinopathy of prematurity (APROP) initially treated with intravitreal ranibizumab (IVR) injection as well as the efficacy of IVR treatment.METHODS: This was a retrospective study. A total of 83 ... | ['Angiogenesis Inhibitors', 'China', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Infant, Newborn', 'Infant, Premature', 'Intravitreal Injections', 'Male', 'Prognosis', 'Ranibizumab', 'Retina', 'Retinal Detachment', 'Retinopathy of Prematurity', 'Retrospective Studies', 'Risk Factors', 'Severity of Illness In... | 29,940,900 | [['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['Z01.252.474.164'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Skeletal uptake of diphosphonate. Method for prediction of post-menopausal osteoporosis. | 24-h whole-body retention (WBR) of diphosphonate (a sensitive indicator of skeletal metabolism) was measured in 37 oophorectomised women. 14 women had been prescribed oestrogen supplements and 3 of these had defaulted from therapy. For the study group there was a significant correlation between WBR and both the rate of... | ['Aged', 'Bone and Bones', 'Castration', 'Clinical Trials as Topic', 'Diphosphonates', 'Double-Blind Method', 'Estrogens', 'Female', 'Humans', 'Menopause', 'Middle Aged', 'Osteoporosis'] | 6,106,785 | [['M01.060.116.100'], ['A02.835.232', 'A10.165.265'], ['E04.270.282', 'E04.950.165'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D02.705.429.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D27.505.696.399.472.277'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Intramedullary epidermoid cyst in the thoracic spine of a dog. | A 5 yr old female spayed mastiff was evaluated for a 3-4 mo history of paraparesis and 3 days of acutely worse paraparesis and incontinence. On magnetic resonance imaging, a spinal cord lesion was present at the ninth thoracic vertebra. The lesion was hyperintense on T2-weighted images (T2-W), and a hyperintense rim wa... | ['Animals', 'Central Nervous System Cysts', 'Diagnosis, Differential', 'Dog Diseases', 'Dogs', 'Epidermal Cyst', 'Female', 'Magnetic Resonance Imaging', 'Thoracic Vertebrae'] | 22,058,362 | [['B01.050'], ['C04.588.614.250.387', 'C10.500.142', 'C10.551.240.375', 'C16.131.666.142'], ['E01.171'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['C04.182.254'], ['E01.370.350.825.500'], ['A02.835.232.834.892']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comprehensive mapping of human body skin hydration: A pilot study. | BACKGROUND: Previous studies analyzed a series of representative anatomical regions in the human body; however, there is a wide structural and cellular variability in the constitution of the skin. Our objective was to perform a comprehensive assessment of human skin hydration throughout the largest possible area.MATERI... | ['Adult', 'Body Surface Potential Mapping', 'Body Water', 'Cross-Sectional Studies', 'Human Body', 'Humans', 'Male', 'Organism Hydration Status', 'Pilot Projects', 'Skin', 'Skin Diseases', 'Skin Physiological Phenomena'] | 30,302,824 | [['M01.060.116'], ['E01.370.370.380.240.850.100', 'E01.370.405.240.850.100'], ['A12.207.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.076.201.450.560', 'K01.093.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.670'], ['E05.318.372.750', 'E05.337.737', 'N05.715.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Small versus large diameter closed-section femoral nails for the treatment of femoral shaft fractures: is there a difference? | UNLABELLED: A retrospective series of 99 femoral shaft fractures treated by small diameter (10 and 11 mm) and large diameter (> 11 mm) closed section femoral nails from November 1989 to September 1993 was analyzed. No significant differences in the parameters of bony union and time to full weight bearing were seen betw... | ['Adult', 'Bone Nails', 'Equipment Failure', 'Female', 'Femoral Fractures', 'Fracture Fixation, Intramedullary', 'Fracture Healing', 'Humans', 'Length of Stay', 'Male', 'Retrospective Studies'] | 8,760,537 | [['M01.060.116'], ['E07.695.370.249', 'E07.858.442.660.460.249', 'E07.858.690.725.460.249'], ['E05.325'], ['C26.404.061', 'C26.558.276'], ['E04.555.300.300.300'], ['G16.762.891.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['E05.318.372.500.500.500', 'E05.318.372.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Promoting HPV Vaccination Online: Message Design and Media Choice. | We investigated the effects of message framing and online media channel on young adults' perceived severity of human papillomavirus (HPV), perceived barriers and benefits of getting HPV vaccination, and behavioral intention to get vaccinated. An experiment was conducted with 142 college students. We found an interactio... | ['Adult', 'Choice Behavior', 'Female', 'Health Promotion', 'Humans', 'Male', 'Newspapers as Topic', 'Papillomavirus Vaccines', 'Patient Acceptance of Health Care', 'Severity of Illness Index', 'Social Media', 'Young Adult'] | 28,129,691 | [['M01.060.116'], ['F02.463.785.373.346'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.682.829.481'], ['D20.215.894.899.498'], ['F01.100.150.750.500', 'F01.145.488.887.500', 'N05.300.150.800.500'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.37... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Early hospital discharge and the timing of newborn metabolic screening. | Cost containment measures have reduced dramatically the length of stay for normal newborns, in some cases jeopardizing the ability to obtain appropriate newborn screens. In our hospital, we found that an unacceptable number of patients had mistakenly been screened before 24 hours of age. As pressures to shorten hospita... | ['Cesarean Section', 'Delivery, Obstetric', 'Health Maintenance Organizations', 'Hospitals, Private', 'Hospitals, Teaching', 'Humans', 'Infant, Newborn', 'Insurance, Health', 'Medicaid', 'Neonatal Screening', 'Nurseries, Hospital', 'Patient Discharge', 'Social Security', 'Time Factors', 'United States'] | 8,403,744 | [['E04.520.252.500'], ['E04.520.252'], ['N03.219.521.576.343.800.400', 'N03.219.521.576.343.925.400', 'N04.452.758.244.425', 'N04.590.374.410.400'], ['N02.278.421.481'], ['N02.278.020.300', 'N02.278.421.639'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['N03.219.521.576.343'], ['N03.219.521.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Nuclear crease as a cytodiagnostic feature of papillary thyroid carcinoma in fine-needle aspiration biopsies. | Nuclear crease or grooving was found to be a diagnostic feature of papillary thyroid carcinoma (PTC) in fine-needle aspiration (FNA) biopsies. The FNA biopsies of 37 cases of PTC, 50 cases of multinodular goiter, and 50 cases of follicular neoplasms (45 follicular adenomas and five follicular carcinomas) were examined.... | ['Biopsy, Needle', 'Carcinoma, Papillary', 'Cell Nucleus', 'Cytodiagnosis', 'Humans', 'Thyroid Neoplasms'] | 3,428,064 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E01.370.225.500.384', 'E05.200.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hemorrhagic preconditioning improves vascular reactivity after hemorrhagic shock by activation of PKCá and PKCå via the adenosine A1 receptor in rats. | BACKGROUND: Our previous study demonstrated that protein kinase C (PKC) has an important protective role on vascular reactivity and calcium sensitivity after shock. Here, we investigated if hemorrhagic preconditioning could lessen shock-induced vascular hyporeactivity by activating PKC.METHODS: Using hemorrhagic-shocke... | ['Adenosine', 'Adenosine A1 Receptor Antagonists', 'Animals', 'Blood Vessels', 'Calcium', 'Enzyme Activation', 'Female', 'Ischemic Preconditioning', 'Male', 'Protein Kinase C-alpha', 'Protein Kinase C-epsilon', 'Rats', 'Rats, Wistar', 'Receptor, Adenosine A1', 'Shock, Hemorrhagic'] | 23,609,277 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D27.505.519.625.725.400.100.100', 'D27.505.696.577.725.400.100.100'], ['B01.050'], ['A07.015'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.263', 'G03.328'], ['E02.592', 'E05.516'], ['D08.811.913.696.620.682.700.725.100'], ['D08.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adhesive capsulitis of the hip: three case reports. | PURPOSE: To describe the diagnosis and treatment of adhesive capsulitis of the hip (ACH).METHOD: A literature review and consideration of three case reports.DISCUSSION: Adhesive capsulitis of the hip is a supposedly rare but probably underestimated condition which predominantly affects middle-aged women. Clinical asses... | ['Adult', 'Aged', 'Bursitis', 'Diagnosis, Differential', 'Female', 'Hip Joint', 'Humans', 'Male', 'Radiography'] | 18,502,531 | [['M01.060.116'], ['M01.060.116.100'], ['C05.550.251'], ['E01.171'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evidence for the early prenatal development of cortical cholinergic afferents from the nucleus of Meynert in the human foetus. | A combined histochemical and biochemical approach has shown that the cholinergic system in the nucleus of Meynert region of the substantia innominata is well defined both histochemically and neurochemically within the first 3 months of gestation in the human foetus. Thus, at between 12 and 22 weeks of development the m... | ['Acetylcholinesterase', 'Afferent Pathways', 'Basal Ganglia', 'Cerebral Cortex', 'Choline O-Acetyltransferase', 'Cholinergic Fibers', 'Histocytochemistry', 'Humans', 'Substantia Innominata'] | 4,080,261 | [['D08.811.277.352.100.170.176'], ['A08.612.220'], ['A08.186.211.200.885.287.249'], ['A08.186.211.200.885.287.500'], ['D08.811.913.050.134.180'], ['A08.675.127.500', 'A08.675.542.234', 'A11.671.188.500', 'A11.671.501.234'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.10... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Short double-stranded ribonucleic acid as inhibitor of gene expression by the interference mechanism. | The rapid development of the small interfering ribonucleic acid (siRNA)-induced inhibition of the gene expression at the RNA level offers to research groups a new strategy for the understanding of gene functions. The siRNA approach is close to antisense oligonucleotide technology and takes advantage of the progress of ... | ['Base Sequence', 'Gene Expression Regulation', 'RNA, Double-Stranded', 'RNA, Small Interfering'] | 15,333,918 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.308'], ['D13.444.735.490', 'G02.111.570.820.486.775', 'G05.360.580.775'], ['D13.150.650.700', 'D13.444.735.150.700', 'D13.444.735.790.552.875']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cadmium, lead and zinc concentrations in water, sediment and oyster (Crassostrea virginica) of San Andres Lagoon, Mexico. | The spatial distribution of cadmium, lead and zinc concentrations in water, sediment and oysters from San Andres Lagoon was evaluated. Significantly higher cadmium (0.33 mg L(-1)) and lead (0.70 mg L(-1)) concentrations in water were observed in front of the mouth of Tigre river, whereas, zinc concentration (5.0 mg L(-... | ['Animals', 'Cadmium', 'Crassostrea', 'Environmental Monitoring', 'Geologic Sediments', 'Lead', 'Mexico', 'Seawater', 'Water Pollutants, Chemical', 'Zinc'] | 21,336,861 | [['B01.050'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['B01.050.500.644.080.643.150'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.330', 'G16.500.320'], ['D01.268.556.435', 'D01.552.544.435'], ['Z01.107.567.589'], ['G16.500.275.725.500'], ['D27.888.284.903.655'], ['D01.268.556.940', 'D01.26... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The genetic polymorphisms of cathepsin S were associated with metabolic disorders in a Chinese Han population. | Cathepsin S (CTSS) played an important role in the etiology of cardiovascular disease and metabolic syndrome. Few studies had been reported on the association between the polymorphisms of CTSS and metabolic disorders in Asian population. Therefore we explored the association between the polymorphisms of CTSS and metabo... | ['Adult', 'Aged', 'Asian Continental Ancestry Group', 'Case-Control Studies', 'Cathepsins', 'China', 'Female', 'Gene Frequency', 'Genetic Association Studies', 'Genotype', 'Humans', 'Male', 'Metabolic Diseases', 'Middle Aged', 'Polymorphism, Genetic', 'Polymorphism, Single Nucleotide', 'Risk Factors', 'Young Adult'] | 23,747,398 | [['M01.060.116'], ['M01.060.116.100'], ['M01.686.508.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D08.811.277.656.224'], ['Z01.252.474.164'], ['G05.330'], ['E05.393.385'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452'], ['M01.060.116.630'], ['G05.365... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Infant feeding, HIV transmission and mortality at 18 months: the need for appropriate choices by mothers and prioritization within programmes. | OBJECTIVES: To determine the late HIV transmission and survival risks associated with early infant feeding practices.DESIGN: A nonrandomized intervention cohort.METHODS: HIV-infected pregnant women were supported in their infant feeding choices. Infant feeding data were obtained weekly; blood samples from infants were ... | ['AIDS Serodiagnosis', 'Adolescent', 'Adult', 'Anti-HIV Agents', 'Breast Feeding', 'CD4 Lymphocyte Count', 'Choice Behavior', 'Developing Countries', 'Female', 'HIV Infections', 'HIV-1', 'Health Knowledge, Attitudes, Practice', 'Health Priorities', 'Humans', 'Infant', 'Infant Mortality', 'Infant, Newborn', 'Male', 'Nev... | 18,981,775 | [['E01.370.225.812.735.060', 'E01.370.225.875.408.500', 'E05.200.812.735.060', 'E05.200.875.408.500', 'E05.478.594.760.060'], ['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.388.077.088'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['E01.370.225.500.195.107.595.500.150... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Gonadal hormone regulation of glial fibrillary acidic protein immunoreactivity and glial ultrastructure in the rat neuroendocrine hypothalamus. | The influence of gonadal steroids on the ultrastructure of glial cells and on the immunoreactivity for the specific astrocytic marker glial fibrillary acidic protein (GFAP) has been assessed in the neuroendocrine hypothalamus. The following parameters were analyzed in the arcuate nucleus of adult female rats: the numbe... | ['Animals', 'Arcuate Nucleus of Hypothalamus', 'Estradiol', 'Estrus', 'Female', 'Glial Fibrillary Acidic Protein', 'Gonadotropins, Pituitary', 'Hypothalamus', 'Immunohistochemistry', 'Microscopy, Electron', 'Neuroglia', 'Neurosecretory Systems', 'Ovariectomy', 'Progesterone', 'Rats', 'Rats, Wistar', 'Tissue Fixation'] | 8,300,192 | [['B01.050'], ['A08.186.211.180.497.352.081', 'A08.186.211.200.317.357.352.081'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G08.686.195.500'], ['D05.750.078.593.400', 'D12.776.220.475.400'], ['D06.472.699.322.576', 'D06.472.699.631.525.343', 'D12.644.548.691.525.343'], ['A08.186.211.180.497', 'A08.186.2... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
First FDA approval of dual anti-HER2 regimen: pertuzumab in combination with trastuzumab and docetaxel for HER2-positive metastatic breast cancer. | On June 8, 2012, the U.S. Food and Drug Administration (FDA) approved pertuzumab (Perjeta, Genentech) for use in combination with trastuzumab (Herceptin, Genentech) and docetaxel for the treatment of patients with HER2-positive metastatic breast cancer (MBC) who have not received prior anti-HER2 therapy or chemotherapy... | ['Antibodies, Monoclonal, Humanized', 'Antineoplastic Combined Chemotherapy Protocols', 'Docetaxel', 'Drug Approval', 'Female', 'Humans', 'Neoplasm Metastasis', 'Randomized Controlled Trials as Topic', 'Receptor, ErbB-2', 'Taxoids', 'Trastuzumab', 'Treatment Outcome', 'United States', 'United States Food and Drug Admin... | 23,801,166 | [['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D02.455.426.392.368.242.888.389', 'D02.455.849.291.850.389'], ['E05.290.250', 'E05.337.300', 'I01.880.604.605.250.250'], ['B01.050.150.900.649.313.988.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Can Abdominal Computed Tomography Imaging Help Accurately Identify a Dedifferentiated Component in a Well-Differentiated Liposarcoma? | PURPOSE: To assess the ability of computed tomography (CT) to differentiate an atypical lipomatous tumor/well-differentiated liposarcoma (WDLPS) from a WDLPS with a dedifferentiated component (DDLPS) within it.MATERIALS AND METHODS: Forty-nine untreated patients with abdominal atypical lipomatous tumors/well-differenti... | ['Abdominal Neoplasms', 'Adult', 'Diagnosis, Differential', 'Female', 'Humans', 'Liposarcoma', 'Male', 'Middle Aged', 'Observer Variation', 'Radiography, Abdominal', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Tomography, X-Ray Computed'] | 27,454,788 | [['C04.588.033'], ['M01.060.116'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.550.420', 'C04.557.450.795.465'], ['M01.060.116.630'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E01.370.350.700.715'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Temporally distinct phosphorylations differentiate Tau-dependent learning deficits and premature mortality in Drosophila. | Abnormally phosphorylated Tau protein, the major component of neurofibrillary tangles, is critical in the pathogenesis of Alzheimer's disease and related Tauopathies. We used Drosophila to examine the role of key disease-associated phosphorylation sites on Tau-mediated neurotoxicity. We present evidence that the late-a... | ['Adult', 'Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Amino Acid Motifs', 'Animals', 'Brain', 'Disease Models, Animal', 'Female', 'Humans', 'Learning', 'Male', 'Mice', 'Middle Aged', 'Mortality, Premature', 'Neurofibrillary Tangles', 'Phosphorylation', 'tau Proteins'] | 25,524,708 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['B01.050'], ['A08.186.211'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Infarct fogging on immediate postinterventional CT-a not infrequent occurrence. | PURPOSE: A pseudo-normalization of infarcted brain parenchyma, similar to the "fogging effect" which usually occurs after 2-3 weeks, can be observed on CT performed immediately after endovascular stroke treatment (EST). Goal of this study was to analyze the incidence of this phenomenon and its evolution on follow-up im... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Brain Infarction', 'Child', 'Child, Preschool', 'Contrast Media', 'Endovascular Procedures', 'Extravasation of Diagnostic and Therapeutic Materials', 'Female', 'Humans', 'Male', 'Middle Aged', 'Registries', 'Retrospective Studies', 'Tomography, X-Ray Computed', 'Tre... | 28,776,270 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300.150.477', 'C10.228.140.300.775.200', 'C14.907.253.092.477', 'C14.907.253.855.200', 'C23.550.513.355.250', 'C23.550.717.489.250'], ['M01.060.406'], ['M01.060.406.448'], ['D27.505.259.500', 'D27.720.259'], ['E04.100.814.529... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Long-term efficacy of a 0.07% cetylpyridinium chloride mouth rinse in relation to plaque and gingivitis: a 6-month randomized, vehicle-controlled clinical trial. | OBJECTIVE: To evaluate the effectiveness of 0.07% cetylpyridinium chloride (CPC) mouth rinse for reduction of gingival inflammation and inhibition of plaque compared to a vehicle control (VC) mouth rinse over a 6-month period.MATERIALS & METHODS: Participants (n = 62) used their randomly assigned product as adjunct to ... | ['Adolescent', 'Adult', 'Anti-Infective Agents, Local', 'Bacteria, Aerobic', 'Bacteria, Anaerobic', 'Bacterial Load', 'Cetylpyridinium', 'Dental Plaque', 'Double-Blind Method', 'Female', 'Follow-Up Studies', 'Gingival Hemorrhage', 'Gingivitis', 'Humans', 'Lactobacillus', 'Longitudinal Studies', 'Male', 'Mouthwashes', '... | 25,040,299 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.187'], ['B03.120'], ['B03.130'], ['E01.370.225.875.150.115', 'E01.370.225.875.220.115', 'E05.200.875.150.115', 'E05.200.875.220.115', 'G06.099.100'], ['D03.383.725.762.232'], ['C07.793.208.377'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
[Regulation of the biomass and activity of soil microorganisms by microfauna]. | Microcosm experiments showed that the microbial biomass and the respiration activity in soil were regulated by nematodes. Depending on nematode number and plant residue composition, the trophic activity of nematodes can either stimulate or inhibit microbial growth and respiration as compared to soil containing no nemat... | ['Animals', 'Bacteria', 'Ecosystem', 'Models, Biological', 'Nematoda', 'Soil Microbiology'] | 11,315,679 | [['B01.050'], ['B03'], ['G16.500.275.157', 'N06.230.124'], ['E05.599.395'], ['B01.050.500.500.294'], ['H01.158.273.540.274.555', 'N06.850.425.300']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Detecting early glaucomatous field defects with the size I stimulus and Statpac. | The influence of stimulus size and normal database on the detection of visual field defects in automated static threshold perimetry (Humphrey Field Analyzer) was investigated in 82 eyes having a diagnosis of normal, glaucoma suspect, or early glaucoma. Using a mathematically derived 'normal' database, which assumes con... | ['Adult', 'Glaucoma', 'Humans', 'Mathematics', 'Middle Aged', 'Models, Biological', 'Sensory Thresholds', 'Visual Field Tests', 'Visual Fields'] | 2,354,137 | [['M01.060.116'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.548'], ['M01.060.116.630'], ['E05.599.395'], ['F02.463.593.710'], ['E01.370.380.850.962'], ['F02.463.593.932.934', 'G14.950']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Lactic acid production in mouse calvaria in vitro with and without parathyroid hormone stimulation: lack of acetazolamide effects. | The effect of acetazolamide on lactic acid production in mouse calvaria explants was examined in an attempt to explain in vivo inhibition of Ca mobilization from bone by sulfonamide inhibitors of carbonic anhydrase. Lactic acid production was evaluated in 8-10-week-old CD-1 mouse calvaria over a time period consistent ... | ['Acetazolamide', 'Animals', 'Bone and Bones', 'Calcium', 'In Vitro Techniques', 'Lactates', 'Lactic Acid', 'Mice', 'Parathyroid Hormone', 'Sulfonamides'] | 3,593,606 | [['D02.886.675.867.060', 'D03.383.129.708.867.060'], ['B01.050'], ['A02.835.232', 'A10.165.265'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.481'], ['D02.241.511.459'], ['D02.241.511.459.450'], ['B01.050.150.900.649.313.992.635.505.500'], ['D06.472.699.590', 'D12.644.548.587'], ['D02.065.884', 'D02.88... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interfacial water structure associated with phospholipid membranes studied by phase-sensitive vibrational sum frequency generation spectroscopy. | Phase-sensitive vibrational sum frequency generation is employed to investigate the water structure at phospholipid/water interfaces. Interfacial water molecules are oriented preferentially by the electrostatic potential imposed by the phospholipids and have, on average, their dipole pointing toward the phospholipid ta... | ['Cell Membrane', 'Hydrogen-Ion Concentration', 'Phospholipids', 'Spectrum Analysis', 'Vibration', 'Water'] | 20,698,700 | [['A11.284.149'], ['G02.300'], ['D10.570.755'], ['E05.196.867'], ['G01.374.930'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
RNA interference screen identifies Usp18 as a regulator of epidermal growth factor receptor synthesis. | Elevated expression of epidermal growth factor receptor (EGFR) contributes to the progression of many types of cancer. Therefore, we developed a high-throughput screen to identify proteins that regulate the levels of EGFR in squamous cell carcinoma. Knocking down various ubiquitination-related genes with small interfer... | ['Animals', 'Cell Line', 'Chlorocebus aethiops', 'Down-Regulation', 'Endopeptidases', 'ErbB Receptors', 'Gene Deletion', 'Genes, Reporter', 'RNA Interference', 'RNA, Messenger', 'Up-Regulation'] | 19,158,387 | [['B01.050'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D08.811.277.656.300'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.360.340... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neuropsychological features in post-stroke cognitive impairment with no dementia patients with different Traditional Chinese Medicine syndromes. | OBJECTIVE: To investigate neuropsychological features of post-stroke cognitive impairment with no dementia (PSCIND) patients with different Traditional Chinese Medicine (TCM) syndromes.METHODS: We recruited 50 patients with PSCIND between April 2012 and March 2013. Patients were divided into different groups according ... | ['Aged', 'Cognitive Dysfunction', 'Drugs, Chinese Herbal', 'Female', 'Humans', 'Male', 'Medicine, Chinese Traditional', 'Middle Aged', 'Neuropsychological Tests', 'Prospective Studies', 'Stroke'] | 32,186,029 | [['M01.060.116.100'], ['F03.615.250.700'], ['D20.215.784.500.350', 'D26.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['M01.060.116.630'], ['F04.711.513'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C10.2... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Sexual differentiation of mammalian frontal cortex. | The pattern of distribution of the progesterone binding sites was examined in selected nuclei of the brain of male and female rat. In female rats the frontal cortex resulted to be the region with the highest concentration of 3H R5020 binding sites. However, in male rats the same region showed very little progestin bind... | ['Animals', 'Brain', 'Castration', 'Female', 'Frontal Lobe', 'Male', 'Promegestone', 'Rats', 'Rats, Inbred Strains', 'Receptors, Progesterone', 'Sex Characteristics', 'Tissue Distribution', 'Tritium'] | 3,561,146 | [['B01.050'], ['A08.186.211'], ['E04.270.282', 'E04.950.165'], ['A08.186.211.200.885.287.500.270'], ['D04.210.500.668.651.443.680'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D12.776.826.750.765'], ['G08.686.815'], ['G03.787.917', 'G07.690... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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